Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   V6U62_RS00760 Genome accession   NZ_CP145860
Coordinates   147756..148697 (+) Length   313 a.a.
NCBI ID   WP_002885658.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 142756..153697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U62_RS00750 (V6U62_00745) rpoC 143512..147149 (+) 3638 Protein_143 DNA-directed RNA polymerase subunit beta' -
  V6U62_RS00755 (V6U62_00750) - 147312..147674 (+) 363 WP_002887019.1 DUF1033 family protein -
  V6U62_RS00760 (V6U62_00755) comYA 147756..148697 (+) 942 WP_002885658.1 competence type IV pilus ATPase ComGA Machinery gene
  V6U62_RS00765 (V6U62_00760) comYB 148579..149679 (+) 1101 WP_144429890.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6U62_RS00770 (V6U62_00765) comYC 149676..150002 (+) 327 WP_002885815.1 competence type IV pilus major pilin ComGC Machinery gene
  V6U62_RS00775 (V6U62_00770) comYD 149962..150390 (+) 429 WP_253183813.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6U62_RS00780 (V6U62_00775) comGE 150422..150652 (+) 231 WP_021144685.1 competence type IV pilus minor pilin ComGE -
  V6U62_RS00785 (V6U62_00780) comYF 150639..151076 (+) 438 WP_227071977.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6U62_RS00790 (V6U62_00785) comGG 151054..151371 (+) 318 WP_227071976.1 competence type IV pilus minor pilin ComGG -
  V6U62_RS00795 (V6U62_00790) comYH 151416..152372 (+) 957 WP_227071975.1 class I SAM-dependent methyltransferase Machinery gene
  V6U62_RS00800 (V6U62_00795) - 152429..153622 (+) 1194 WP_410535066.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35283.27 Da        Isoelectric Point: 5.4492

>NTDB_id=940284 V6U62_RS00760 WP_002885658.1 147756..148697(+) (comYA) [Streptococcus salivarius strain KSS2]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVQQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=940284 V6U62_RS00760 WP_002885658.1 147756..148697(+) (comYA) [Streptococcus salivarius strain KSS2]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTACGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTATCAACCGTTGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGAATTGGTGTATTGGAATCAAGGAATCCAGCCGATTATGGATGCTTTGGATTATCGTGGCT
TGTATCTCTTTGCAGGTCCCGTAGGTTCTGGAAAGACTACGCTTATGCATGAATTGGTTCAGGAGCGTTTTAAGGGACAG
CAGGTGATTTCGATTGAAGATCCTGTGGAAATTAAACAGGATAATGTCTTGCAACTCCAGGTAAATCAGGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTACGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACAGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTTGGTGTAGATAAGTCTGAGTTGGATAATGCTCTTCAAGGGATTGCCTATATGCGTTTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTCAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

65.176

100

0.652
  comYA Streptococcus mutans UA140

65.176

100

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.309

99.361

0.639
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361