Detailed information NTG0940285

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: V6U62_RS00765
• Genome accession: NZ_CP145860
• Coordinates: 148579..149679 (+)
• Length: 366 a.a.
• NCBI ID: WP_144429890.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS2
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 143579..154679

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U62_RS00755 (V6U62_00750)	-	147312..147674 (+)	363	WP_002887019.1	DUF1033 family protein	-
V6U62_RS00760 (V6U62_00755)	comYA	147756..148697 (+)	942	WP_002885658.1	competence type IV pilus ATPase ComGA	Machinery gene
V6U62_RS00765 (V6U62_00760)	comYB	148579..149679 (+)	1101	WP_144429890.1	competence type IV pilus assembly protein ComGB	Machinery gene
V6U62_RS00770 (V6U62_00765)	comYC	149676..150002 (+)	327	WP_002885815.1	competence type IV pilus major pilin ComGC	Machinery gene
V6U62_RS00775 (V6U62_00770)	comYD	149962..150390 (+)	429	WP_253183813.1	competence type IV pilus minor pilin ComGD	Machinery gene
V6U62_RS00780 (V6U62_00775)	comGE	150422..150652 (+)	231	WP_021144685.1	competence type IV pilus minor pilin ComGE	-
V6U62_RS00785 (V6U62_00780)	comYF	150639..151076 (+)	438	WP_227071977.1	competence type IV pilus minor pilin ComGF	Machinery gene
V6U62_RS00790 (V6U62_00785)	comGG	151054..151371 (+)	318	WP_227071976.1	competence type IV pilus minor pilin ComGG	-
V6U62_RS00795 (V6U62_00790)	comYH	151416..152372 (+)	957	WP_227071975.1	class I SAM-dependent methyltransferase	Machinery gene
V6U62_RS00800 (V6U62_00795)	-	152429..153622 (+)	1194	WP_410535066.1	acetate kinase	-
V6U62_RS00805 (V6U62_00800)	-	153873..154070 (+)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41648.61 Da
• Isoelectric Point: 9.9778

>NTDB_id=940285 V6U62_RS00765 WP_144429890.1 148579..149679(+) (comYB) [Streptococcus salivarius strain KSS2]
MPVKISKAIRQPAGTNSWKAWFNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKDNWAVQLVQIFPQLFFVSLCGLLVLSLILYLWVKHQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSNLFRELGADLEEALMLGQSFPDRIATHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=940285 V6U62_RS00765 WP_144429890.1 148579..149679(+) (comYB) [Streptococcus salivarius strain KSS2]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAGGCTTGGTTCAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACTTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCGTCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGCATGACCAAGGTTC
GCAAGAAACTCATGGAGGTAGCGACCTACCCTATCCTACTCCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCTCAACTGTTAGAGGGTGATGGTAAGGATAATTGGGCTGTACAGTTGGTTCAAATCTTTCCCCAGCTCTT
CTTTGTGAGTTTGTGTGGACTTCTTGTATTAAGCTTAATTCTTTATCTATGGGTCAAACACCAGCCAGCCCTTGTCTTTT
ACCGACGAATGGCAAAAATCCCTTTCATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGACAAGGCATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCTAATCTCTTTCGTGAGCT
GGGGGCTGATTTAGAAGAGGCCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTACTCACCCTTTTTTCACTAAGG
AACTATCCTTGATTATTGCTTATGGAGAGGCCAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCTATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	55.102	93.716	0.516
comYB	Streptococcus mutans UA159	55.102	93.716	0.516
comYB	Streptococcus gordonii str. Challis substr. CH1	51.02	93.716	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.144	94.809	0.475
comGB/cglB	Streptococcus mitis SK321	49.704	92.35	0.459
comGB/cglB	Streptococcus pneumoniae Rx1	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae D39	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae R6	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae TIGR4	49.408	92.35	0.456
comGB	Lactococcus lactis subsp. cremoris KW2	45.646	90.984	0.415