Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   VKP36_RS00650 Genome accession   NZ_CP142357
Coordinates   101882..102820 (+) Length   312 a.a.
NCBI ID   WP_129304381.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain AW-534     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 96882..107820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP36_RS00640 (VKP36_00640) rpoC 97631..101272 (+) 3642 WP_011284419.1 DNA-directed RNA polymerase subunit beta' -
  VKP36_RS00645 (VKP36_00645) - 101424..101789 (+) 366 WP_002986560.1 DUF1033 family protein -
  VKP36_RS00650 (VKP36_00650) comYA 101882..102820 (+) 939 WP_129304381.1 competence type IV pilus ATPase ComGA Machinery gene
  VKP36_RS00655 (VKP36_00655) comYB 102756..103790 (+) 1035 WP_227868552.1 competence type IV pilus assembly protein ComGB Machinery gene
  VKP36_RS00660 (VKP36_00660) comYC 103792..104118 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  VKP36_RS00665 (VKP36_00665) comGD 104093..104521 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  VKP36_RS00670 (VKP36_00670) comGE 104478..104762 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  VKP36_RS00675 (VKP36_00675) comYF 104755..105189 (+) 435 WP_326624919.1 competence type IV pilus minor pilin ComGF Machinery gene
  VKP36_RS00680 (VKP36_00680) comGG 105173..105499 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  VKP36_RS00685 (VKP36_00685) comYH 105597..106550 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  VKP36_RS00690 (VKP36_00690) - 106609..107805 (+) 1197 WP_030126459.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35032.31 Da        Isoelectric Point: 8.5780

>NTDB_id=925354 VKP36_RS00650 WP_129304381.1 101882..102820(+) (comYA) [Streptococcus pyogenes strain AW-534]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERKLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YVRLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=925354 VKP36_RS00650 WP_129304381.1 101882..102820(+) (comYA) [Streptococcus pyogenes strain AW-534]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAAATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAAGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAGTTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGTAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

61.093

99.679

0.609
  comYA Streptococcus mutans UA159

61.093

99.679

0.609
  comYA Streptococcus gordonii str. Challis substr. CH1

60.45

99.679

0.603
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.323

99.359

0.599
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.679

0.596
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.164

99.679

0.59
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

38.966

92.949

0.362