Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   VKP36_RS00685 Genome accession   NZ_CP142357
Coordinates   105597..106550 (+) Length   317 a.a.
NCBI ID   WP_010921802.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain AW-534     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 100597..111550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP36_RS00645 (VKP36_00645) - 101424..101789 (+) 366 WP_002986560.1 DUF1033 family protein -
  VKP36_RS00650 (VKP36_00650) comYA 101882..102820 (+) 939 WP_129304381.1 competence type IV pilus ATPase ComGA Machinery gene
  VKP36_RS00655 (VKP36_00655) comYB 102756..103790 (+) 1035 WP_227868552.1 competence type IV pilus assembly protein ComGB Machinery gene
  VKP36_RS00660 (VKP36_00660) comYC 103792..104118 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  VKP36_RS00665 (VKP36_00665) comGD 104093..104521 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  VKP36_RS00670 (VKP36_00670) comGE 104478..104762 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  VKP36_RS00675 (VKP36_00675) comYF 104755..105189 (+) 435 WP_326624919.1 competence type IV pilus minor pilin ComGF Machinery gene
  VKP36_RS00680 (VKP36_00680) comGG 105173..105499 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  VKP36_RS00685 (VKP36_00685) comYH 105597..106550 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  VKP36_RS00690 (VKP36_00690) - 106609..107805 (+) 1197 WP_030126459.1 acetate kinase -
  VKP36_RS00695 (VKP36_00695) - 107991..108299 (+) 309 WP_030126458.1 hypothetical protein -
  VKP36_RS00700 (VKP36_00700) proC 108382..109152 (-) 771 WP_002992745.1 pyrroline-5-carboxylate reductase -
  VKP36_RS00705 (VKP36_00705) pepA 109199..110266 (-) 1068 WP_136105159.1 glutamyl aminopeptidase -
  VKP36_RS00710 (VKP36_00710) - 110732..111016 (+) 285 WP_326624924.1 DUF4651 domain-containing protein -
  VKP36_RS00715 (VKP36_00715) - 111013..111330 (+) 318 WP_002986515.1 thioredoxin family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 36015.10 Da        Isoelectric Point: 4.7205

>NTDB_id=925358 VKP36_RS00685 WP_010921802.1 105597..106550(+) (comYH) [Streptococcus pyogenes strain AW-534]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=925358 VKP36_RS00685 WP_010921802.1 105597..106550(+) (comYH) [Streptococcus pyogenes strain AW-534]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-288)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

65.823

99.685

0.656
  comYH Streptococcus mutans UA140

65.506

99.685

0.653