Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   VKP55_RS00905 Genome accession   NZ_CP142351
Coordinates   143741..144067 (+) Length   108 a.a.
NCBI ID   WP_326674280.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain SS1366     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 138741..149067
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP55_RS00890 (VKP55_00890) - 141373..141738 (+) 366 WP_002986560.1 DUF1033 family protein -
  VKP55_RS00895 (VKP55_00895) comYA 141831..142769 (+) 939 WP_326674278.1 competence type IV pilus ATPase ComGA Machinery gene
  VKP55_RS00900 (VKP55_00900) comYB 142705..143739 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  VKP55_RS00905 (VKP55_00905) comYC 143741..144067 (+) 327 WP_326674280.1 competence type IV pilus major pilin ComGC Machinery gene
  VKP55_RS00910 (VKP55_00910) comGD 144042..144470 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  VKP55_RS00915 (VKP55_00915) comGE 144427..144711 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  VKP55_RS00920 (VKP55_00920) comYF 144704..145138 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  VKP55_RS00925 (VKP55_00925) comGG 145122..145448 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  VKP55_RS00930 (VKP55_00930) comYH 145546..146499 (+) 954 WP_326674282.1 class I SAM-dependent methyltransferase Machinery gene
  VKP55_RS00935 (VKP55_00935) - 146558..147754 (+) 1197 WP_326674284.1 acetate kinase -
  VKP55_RS00940 (VKP55_00940) - 147940..148248 (+) 309 WP_326674286.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12431.45 Da        Isoelectric Point: 10.0726

>NTDB_id=925028 VKP55_RS00905 WP_326674280.1 143741..144067(+) (comYC) [Streptococcus pyogenes strain SS1366]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTERGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=925028 VKP55_RS00905 WP_326674280.1 143741..144067(+) (comYC) [Streptococcus pyogenes strain SS1366]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAAGAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

55.238

97.222

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

54.167

88.889

0.481
  comYC Streptococcus mutans UA159

54.167

88.889

0.481
  comYC Streptococcus suis isolate S10

59.259

75

0.444