Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   VKP55_RS00895 Genome accession   NZ_CP142351
Coordinates   141831..142769 (+) Length   312 a.a.
NCBI ID   WP_326674278.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain SS1366     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 136831..147769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP55_RS00885 (VKP55_00885) rpoC 137598..141221 (+) 3624 WP_011527438.1 DNA-directed RNA polymerase subunit beta' -
  VKP55_RS00890 (VKP55_00890) - 141373..141738 (+) 366 WP_002986560.1 DUF1033 family protein -
  VKP55_RS00895 (VKP55_00895) comYA 141831..142769 (+) 939 WP_326674278.1 competence type IV pilus ATPase ComGA Machinery gene
  VKP55_RS00900 (VKP55_00900) comYB 142705..143739 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  VKP55_RS00905 (VKP55_00905) comYC 143741..144067 (+) 327 WP_326674280.1 competence type IV pilus major pilin ComGC Machinery gene
  VKP55_RS00910 (VKP55_00910) comGD 144042..144470 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  VKP55_RS00915 (VKP55_00915) comGE 144427..144711 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  VKP55_RS00920 (VKP55_00920) comYF 144704..145138 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  VKP55_RS00925 (VKP55_00925) comGG 145122..145448 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  VKP55_RS00930 (VKP55_00930) comYH 145546..146499 (+) 954 WP_326674282.1 class I SAM-dependent methyltransferase Machinery gene
  VKP55_RS00935 (VKP55_00935) - 146558..147754 (+) 1197 WP_326674284.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35002.25 Da        Isoelectric Point: 8.5799

>NTDB_id=925026 VKP55_RS00895 WP_326674278.1 141831..142769(+) (comYA) [Streptococcus pyogenes strain SS1366]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMAYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=925026 VKP55_RS00895 WP_326674278.1 141831..142769(+) (comYA) [Streptococcus pyogenes strain SS1366]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAGTTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GGCTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

61.415

99.679

0.612
  comYA Streptococcus mutans UA140

61.415

99.679

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

60.45

99.679

0.603
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.323

99.359

0.599
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.486

99.679

0.593
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.842

99.679

0.587
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

39.655

92.949

0.369