Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   VKP35_RS00785 Genome accession   NZ_CP142349
Coordinates   120823..121149 (+) Length   108 a.a.
NCBI ID   WP_111713112.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 11RS100     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115823..126149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP35_RS00770 (VKP35_00770) - 118455..118820 (+) 366 WP_002986560.1 DUF1033 family protein -
  VKP35_RS00775 (VKP35_00775) comYA 118913..119851 (+) 939 WP_009880361.1 competence type IV pilus ATPase ComGA Machinery gene
  VKP35_RS00780 (VKP35_00780) comYB 119787..120821 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  VKP35_RS00785 (VKP35_00785) comYC 120823..121149 (+) 327 WP_111713112.1 competence type IV pilus major pilin ComGC Machinery gene
  VKP35_RS00790 (VKP35_00790) comGD 121124..121552 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  VKP35_RS00795 (VKP35_00795) comGE 121509..121793 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  VKP35_RS00800 (VKP35_00800) comYF 121786..122220 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  VKP35_RS00805 (VKP35_00805) comGG 122204..122530 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  VKP35_RS00810 (VKP35_00810) comYH 122628..123581 (+) 954 WP_032467307.1 class I SAM-dependent methyltransferase Machinery gene
  VKP35_RS00815 (VKP35_00815) - 123640..124836 (+) 1197 WP_002986533.1 acetate kinase -
  VKP35_RS00820 (VKP35_00820) - 125023..125331 (+) 309 WP_011017251.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12377.30 Da        Isoelectric Point: 9.3497

>NTDB_id=924919 VKP35_RS00785 WP_111713112.1 120823..121149(+) (comYC) [Streptococcus pyogenes strain 11RS100]
MINQWNNLRHKKLEGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=924919 VKP35_RS00785 WP_111713112.1 120823..121149(+) (comYC) [Streptococcus pyogenes strain 11RS100]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAGAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(14-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

55.238

97.222

0.537
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus mitis SK321

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae R6

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae TIGR4

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae D39

59.783

85.185

0.509
  comGC/cglC Streptococcus mitis NCTC 12261

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae Rx1

59.783

85.185

0.509
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

58.025

75

0.435