Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | VKP35_RS00810 | Genome accession | NZ_CP142349 |
| Coordinates | 122628..123581 (+) | Length | 317 a.a. |
| NCBI ID | WP_032467307.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain 11RS100 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 117628..128581
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VKP35_RS00770 (VKP35_00770) | - | 118455..118820 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| VKP35_RS00775 (VKP35_00775) | comYA | 118913..119851 (+) | 939 | WP_009880361.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| VKP35_RS00780 (VKP35_00780) | comYB | 119787..120821 (+) | 1035 | WP_011054115.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| VKP35_RS00785 (VKP35_00785) | comYC | 120823..121149 (+) | 327 | WP_111713112.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| VKP35_RS00790 (VKP35_00790) | comGD | 121124..121552 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | - |
| VKP35_RS00795 (VKP35_00795) | comGE | 121509..121793 (+) | 285 | WP_002987779.1 | competence type IV pilus minor pilin ComGE | - |
| VKP35_RS00800 (VKP35_00800) | comYF | 121786..122220 (+) | 435 | WP_002986542.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| VKP35_RS00805 (VKP35_00805) | comGG | 122204..122530 (+) | 327 | WP_002986539.1 | competence type IV pilus minor pilin ComGG | - |
| VKP35_RS00810 (VKP35_00810) | comYH | 122628..123581 (+) | 954 | WP_032467307.1 | class I SAM-dependent methyltransferase | Machinery gene |
| VKP35_RS00815 (VKP35_00815) | - | 123640..124836 (+) | 1197 | WP_002986533.1 | acetate kinase | - |
| VKP35_RS00820 (VKP35_00820) | - | 125023..125331 (+) | 309 | WP_011017251.1 | hypothetical protein | - |
| VKP35_RS00825 (VKP35_00825) | proC | 125414..126184 (-) | 771 | WP_002986527.1 | pyrroline-5-carboxylate reductase | - |
| VKP35_RS00830 (VKP35_00830) | pepA | 126232..127299 (-) | 1068 | WP_111713113.1 | glutamyl aminopeptidase | - |
| VKP35_RS00835 (VKP35_00835) | - | 127764..128048 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| VKP35_RS00840 (VKP35_00840) | - | 128045..128362 (+) | 318 | WP_002986515.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 36015.16 Da Isoelectric Point: 4.7205
>NTDB_id=924921 VKP35_RS00810 WP_032467307.1 122628..123581(+) (comYH) [Streptococcus pyogenes strain 11RS100]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALIMLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALIMLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=924921 VKP35_RS00810 WP_032467307.1 122628..123581(+) (comYH) [Streptococcus pyogenes strain 11RS100]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCCCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAACATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTATGCTACCAGATTCTATTTTTGGTCA
TCCCTCTAATGCTAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCCCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAACATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTATGCTACCAGATTCTATTTTTGGTCA
TCCCTCTAATGCTAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
66.139 |
99.685 |
0.659 |
| comYH | Streptococcus mutans UA140 |
65.823 |
99.685 |
0.656 |