Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   VOI49_RS00750 Genome accession   NZ_CP142018
Coordinates   118552..119493 (+) Length   313 a.a.
NCBI ID   WP_003049251.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain lu24     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 113552..124493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VOI49_RS00740 rpoC 114261..117902 (+) 3642 WP_003049245.1 DNA-directed RNA polymerase subunit beta' -
  VOI49_RS00745 - 118106..118471 (+) 366 WP_003049248.1 DUF1033 family protein -
  VOI49_RS00750 comYA 118552..119493 (+) 942 WP_003049251.1 competence type IV pilus ATPase ComGA Machinery gene
  VOI49_RS00755 comYB 119429..120460 (+) 1032 WP_226313561.1 competence type IV pilus assembly protein ComGB Machinery gene
  VOI49_RS00760 comYC 120462..120788 (+) 327 WP_115246891.1 competence type IV pilus major pilin ComGC Machinery gene
  VOI49_RS00765 comGD 120763..121191 (+) 429 WP_324739066.1 competence type IV pilus minor pilin ComGD -
  VOI49_RS00770 comGE 121148..121444 (+) 297 WP_003061797.1 competence type IV pilus minor pilin ComGE -
  VOI49_RS00775 comGF 121485..121865 (+) 381 WP_324739576.1 competence type IV pilus minor pilin ComGF -
  VOI49_RS00780 comGG 121843..122217 (+) 375 WP_003049269.1 competence type IV pilus minor pilin ComGG -
  VOI49_RS00785 comYH 122280..123233 (+) 954 WP_115246884.1 class I SAM-dependent methyltransferase Machinery gene
  VOI49_RS00790 - 123292..124488 (+) 1197 WP_003049273.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35181.29 Da        Isoelectric Point: 7.5609

>NTDB_id=920993 VOI49_RS00750 WP_003049251.1 118552..119493(+) (comYA) [Streptococcus dysgalactiae strain lu24]
MVQALAKSILKEAEQVQAQDIYILPKEDQYELLVRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IGEDTLLSLRLSSVGNYRGQESLVIRLLHHRQRSLHYWFDGLKTVARQIGGRGLYLFAGPVGSGKTTLMHQLIADYYQGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGALVFSTVHAKSISGV
YARLLELGVTRAELDNCLAFVAYQRLLNGGALIDSTQTEFEHYSPNQWNQQIDDLLAAGHLSPKQARIEKIIQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=920993 VOI49_RS00750 WP_003049251.1 118552..119493(+) (comYA) [Streptococcus dysgalactiae strain lu24]
ATGGTACAAGCATTAGCAAAATCTATTTTGAAAGAAGCTGAGCAGGTTCAAGCTCAAGATATCTATATTTTGCCAAAGGA
AGATCAGTATGAGTTATTGGTAAGGGTAGGAGACGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACTGTCGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGGTGAAGACACACTTTTGTCTCTACGCCTATCTAGTGTTGGAAATTACCGTGGACAAGAGAGTTTAGTGATTCGGTT
ACTGCACCATCGACAAAGAAGTTTACACTACTGGTTTGACGGACTGAAAACAGTCGCACGTCAGATTGGAGGCCGAGGGC
TCTATCTTTTTGCAGGTCCAGTCGGATCAGGGAAAACAACTTTGATGCACCAATTGATTGCTGATTATTATCAGGGAGCA
CAGGTCATTAGCATAGAGGATCCGGTGGAAATCAAAAATCATCAAGCGCTCCAATTACAAGTTAATGATAGTATTGGCAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATTATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGCCTTAGTATTTTCAACAGTGCATGCCAAAAGCATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTTGTTGCTTACCAACGATTGCT
TAATGGAGGGGCATTAATTGACTCAACTCAAACAGAATTTGAACACTACTCACCAAACCAATGGAATCAACAAATTGATG
ACCTTCTTGCAGCGGGACATCTCAGTCCGAAGCAAGCAAGGATCGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

62.058

99.361

0.617
  comYA Streptococcus mutans UA159

62.058

99.361

0.617
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

99.042

0.613
  comYA Streptococcus gordonii str. Challis substr. CH1

61.415

99.361

0.61
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

60.772

99.361

0.604
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

60.45

99.361

0.601
  comGA/cglA/cilD Streptococcus pneumoniae D39

60.45

99.361

0.601
  comGA/cglA/cilD Streptococcus pneumoniae R6

60.45

99.361

0.601
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

60.45

99.361

0.601
  comGA Lactococcus lactis subsp. cremoris KW2

50.804

99.361

0.505