Detailed information NTG0920996

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: VOI49_RS00785
• Genome accession: NZ_CP142018
• Coordinates: 122280..123233 (+)
• Length: 317 a.a.
• NCBI ID: WP_115246884.1
• Uniprot ID: A0A380JYU6
• Organism: Streptococcus dysgalactiae strain lu24
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 117280..128233

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VOI49_RS00745	-	118106..118471 (+)	366	WP_003049248.1	DUF1033 family protein	-
VOI49_RS00750	comYA	118552..119493 (+)	942	WP_003049251.1	competence type IV pilus ATPase ComGA	Machinery gene
VOI49_RS00755	comYB	119429..120460 (+)	1032	WP_226313561.1	competence type IV pilus assembly protein ComGB	Machinery gene
VOI49_RS00760	comYC	120462..120788 (+)	327	WP_115246891.1	competence type IV pilus major pilin ComGC	Machinery gene
VOI49_RS00765	comGD	120763..121191 (+)	429	WP_324739066.1	competence type IV pilus minor pilin ComGD	-
VOI49_RS00770	comGE	121148..121444 (+)	297	WP_003061797.1	competence type IV pilus minor pilin ComGE	-
VOI49_RS00775	comGF	121485..121865 (+)	381	WP_324739576.1	competence type IV pilus minor pilin ComGF	-
VOI49_RS00780	comGG	121843..122217 (+)	375	WP_003049269.1	competence type IV pilus minor pilin ComGG	-
VOI49_RS00785	comYH	122280..123233 (+)	954	WP_115246884.1	class I SAM-dependent methyltransferase	Machinery gene
VOI49_RS00790	-	123292..124488 (+)	1197	WP_003049273.1	acetate kinase	-
VOI49_RS00795	-	124798..125004 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
VOI49_RS00800	-	125160..125765 (+)	606	WP_226313560.1	CPBP family intramembrane glutamic endopeptidase	-
VOI49_RS00805	-	125783..126220 (+)	438	WP_003049278.1	hypothetical protein	-
VOI49_RS00810	proC	126359..127135 (-)	777	WP_115246875.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 36018.92 Da
• Isoelectric Point: 4.7910

>NTDB_id=920996 VOI49_RS00785 WP_115246884.1 122280..123233(+) (comYH) [Streptococcus dysgalactiae strain lu24]
MNFEKIEEAYQLLLENSQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNINKLKALHLTKEEWRRAYQFIFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKKLDYVGIELDDLLIDLSASIAEVMDSS
ARFIQEDAVRPQLLKESDVVISDLPVGYYPNDDIAKRYKVASSEEHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSSQ
SQLLKNWLTGYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPTETFVYPIRDLKLAENIHDFMQNFKKWKQDNVN

Nucleotide

• Length: 954 bp

>NTDB_id=920996 VOI49_RS00785 WP_115246884.1 122280..123233(+) (comYH) [Streptococcus dysgalactiae strain lu24]
ATGAATTTTGAAAAAATTGAAGAAGCCTATCAGTTACTTTTAGAGAATAGTCAACTGATTGAAAACGATTTAAAAACACA
TATTTATGATGCAATCGTTGAGCAAAACTCTTTTTATTTAGGTGCTGAGGGAGCTAGTCCTCAAGTTGCCCAGAACATTA
ACAAACTGAAAGCCTTACACCTGACTAAAGAAGAATGGCGTAGAGCTTACCAGTTTATTTTTATTAAGGCAGCTCAGACT
GAGCAGCTCCAAGCAAACCATCAGTTCACGCCAGATGCTATTGGTTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
CAAAGATAGCCTAGAAGTCCTTGAAATTGGCAGTGGTACGGGAAATCTAGCACAAACTCTCCTCAATAATACGAGTAAGA
AACTTGATTATGTAGGGATTGAACTTGACGATCTCTTAATTGATTTATCAGCAAGTATTGCTGAAGTAATGGACTCTTCA
GCTCGTTTTATTCAAGAAGATGCGGTAAGACCGCAATTGTTAAAAGAAAGCGACGTTGTTATCAGTGACTTGCCAGTGGG
TTATTATCCTAATGATGACATTGCTAAGCGCTATAAGGTAGCTAGTTCTGAGGAACACACCTATGCTCATCATTTACTCA
TGGAACAATCTTTAAAGTATTTGAAAAAAGATGGTTTTGCCATTTTCTTGGCACCTGTCAATTTGTTAACAAGCTCTCAG
AGCCAATTGTTGAAAAATTGGTTAACTGGCTATGCCCAGGTAGTGGCCTTGATTACTCTACCAGATTCTATATTTGGTCA
TCCCTCAAATGCTAAGTCCATTATTGTCTTGCAAAAGCAGACAGACCATCCGACGGAAACCTTTGTTTATCCTATTCGAG
ACTTGAAACTTGCAGAGAATATTCATGACTTTATGCAAAATTTCAAAAAATGGAAACAGGATAATGTCAATTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-290)

3D structure

• AlphaFold DB: A0A380JYU6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	66.456	99.685	0.662
comYH	Streptococcus mutans UA159	66.139	99.685	0.659