Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   VF946_RS00730 Genome accession   NZ_CP141824
Coordinates   115623..116573 (+) Length   316 a.a.
NCBI ID   WP_011921718.1    Uniprot ID   -
Organism   Streptococcus suis strain HB18     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 110623..121573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS00720 - 114194..114559 (+) 366 WP_002936568.1 DUF1033 family protein -
  VF946_RS00725 - 114594..115537 (-) 944 Protein_109 S66 peptidase family protein -
  VF946_RS00730 comYA 115623..116573 (+) 951 WP_011921718.1 competence type IV pilus ATPase ComGA Machinery gene
  VF946_RS00735 comYB 116485..117522 (+) 1038 WP_256770774.1 competence type IV pilus assembly protein ComGB Machinery gene
  VF946_RS00740 comYC 117524..117805 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  VF946_RS00745 comGD 117786..118193 (+) 408 WP_011921721.1 competence type IV pilus minor pilin ComGD -
  VF946_RS00750 comYE 118165..118458 (+) 294 WP_011921722.1 competence type IV pilus minor pilin ComGE Machinery gene
  VF946_RS00755 comGF/cglF 118445..118879 (+) 435 WP_011922561.1 competence type IV pilus minor pilin ComGF Machinery gene
  VF946_RS00760 comGG 118857..119267 (+) 411 WP_011921724.1 competence type IV pilus minor pilin ComGG -
  VF946_RS00765 comYH 119324..120277 (+) 954 WP_024406069.1 class I SAM-dependent methyltransferase Machinery gene
  VF946_RS00770 - 120327..121514 (+) 1188 WP_012775473.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35412.26 Da        Isoelectric Point: 5.4713

>NTDB_id=919737 VF946_RS00730 WP_011921718.1 115623..116573(+) (comYA) [Streptococcus suis strain HB18]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDDREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVGPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKITLGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=919737 VF946_RS00730 WP_011921718.1 115623..116573(+) (comYA) [Streptococcus suis strain HB18]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCGGATAGGGTCAGTGACATTTATCTGGTTCCTCGTGG
TGAGTGTTACCAAGTCTATCATCGTATCATGGACGATCGGGAATTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGCGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCTAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTTGAAATCAAGCAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACAGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCGGGTGTCTAT
GCTCGTATGTTGGAATTGGGTGTCGGTCCTGAGGAGTTAAACAATGCCCTTCAAGGTATTGCCTATCAACGTTTAATCGG
GGGAGGAGGTGTGGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGGC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTACCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.387

98.101

0.671
  comYA Streptococcus mutans UA159

67.203

98.418

0.661
  comYA Streptococcus mutans UA140

67.203

98.418

0.661
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.63

98.418

0.636
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.63

98.418

0.636
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.63

98.418

0.636
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.63

98.418

0.636
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.63

98.418

0.636
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.516

98.101

0.633
  comGA Lactococcus lactis subsp. cremoris KW2

52.997

100

0.532
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361