Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   VF946_RS00755 Genome accession   NZ_CP141824
Coordinates   118445..118879 (+) Length   144 a.a.
NCBI ID   WP_011922561.1    Uniprot ID   -
Organism   Streptococcus suis strain HB18     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 113445..123879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS00720 - 114194..114559 (+) 366 WP_002936568.1 DUF1033 family protein -
  VF946_RS00725 - 114594..115537 (-) 944 Protein_109 S66 peptidase family protein -
  VF946_RS00730 comYA 115623..116573 (+) 951 WP_011921718.1 competence type IV pilus ATPase ComGA Machinery gene
  VF946_RS00735 comYB 116485..117522 (+) 1038 WP_256770774.1 competence type IV pilus assembly protein ComGB Machinery gene
  VF946_RS00740 comYC 117524..117805 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  VF946_RS00745 comGD 117786..118193 (+) 408 WP_011921721.1 competence type IV pilus minor pilin ComGD -
  VF946_RS00750 comYE 118165..118458 (+) 294 WP_011921722.1 competence type IV pilus minor pilin ComGE Machinery gene
  VF946_RS00755 comGF/cglF 118445..118879 (+) 435 WP_011922561.1 competence type IV pilus minor pilin ComGF Machinery gene
  VF946_RS00760 comGG 118857..119267 (+) 411 WP_011921724.1 competence type IV pilus minor pilin ComGG -
  VF946_RS00765 comYH 119324..120277 (+) 954 WP_024406069.1 class I SAM-dependent methyltransferase Machinery gene
  VF946_RS00770 - 120327..121514 (+) 1188 WP_012775473.1 acetate kinase -
  VF946_RS00775 - 121827..122378 (+) 552 WP_012775474.1 folate family ECF transporter S component -
  VF946_RS00780 - 122434..123690 (+) 1257 WP_012775475.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16491.85 Da        Isoelectric Point: 5.9234

>NTDB_id=919741 VF946_RS00755 WP_011922561.1 118445..118879(+) (comGF/cglF) [Streptococcus suis strain HB18]
MLKSKIPAFTLLECLVVLVILSGSLLIFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVNKGE
QALAFGKSWSDDFRKTNDRGQGYQPMLYQVDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide


Download         Length: 435 bp        

>NTDB_id=919741 VF946_RS00755 WP_011922561.1 118445..118879(+) (comGF/cglF) [Streptococcus suis strain HB18]
TTGTTAAAAAGTAAAATTCCTGCTTTTACACTCTTGGAATGTTTGGTGGTTCTAGTCATTCTGTCAGGTAGCCTCTTGAT
TTTTGAAGGCTTATCCAAATTACTAGTCCAGGAAGCGCATTATCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTCT
CTAGCCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCAACAAAGGTGAA
CAGGCTTTGGCCTTTGGCAAGTCATGGTCGGATGATTTTCGGAAAACAAATGATAGAGGCCAGGGTTACCAACCCATGCT
CTATCAGGTGGATAGCGCAGCCATTTCCCAAGAAAACCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GAACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(37-134)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus pneumoniae TIGR4

52.482

97.917

0.514
  comGF/cglF Streptococcus pneumoniae Rx1

52.482

97.917

0.514
  comGF/cglF Streptococcus pneumoniae D39

52.482

97.917

0.514
  comGF/cglF Streptococcus pneumoniae R6

52.482

97.917

0.514
  comGF/cglF Streptococcus mitis NCTC 12261

52.985

93.056

0.493
  comYF Streptococcus mutans UA140

48.611

100

0.486
  comYF Streptococcus mutans UA159

47.917

100

0.479
  comGF/cglF Streptococcus mitis SK321

50

93.056

0.465
  comGF Lactococcus lactis subsp. cremoris KW2

45.39

97.917

0.444