Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   VF946_RS00735 Genome accession   NZ_CP141824
Coordinates   116485..117522 (+) Length   345 a.a.
NCBI ID   WP_256770774.1    Uniprot ID   -
Organism   Streptococcus suis strain HB18     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 111485..122522
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS00720 - 114194..114559 (+) 366 WP_002936568.1 DUF1033 family protein -
  VF946_RS00725 - 114594..115537 (-) 944 Protein_109 S66 peptidase family protein -
  VF946_RS00730 comYA 115623..116573 (+) 951 WP_011921718.1 competence type IV pilus ATPase ComGA Machinery gene
  VF946_RS00735 comYB 116485..117522 (+) 1038 WP_256770774.1 competence type IV pilus assembly protein ComGB Machinery gene
  VF946_RS00740 comYC 117524..117805 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  VF946_RS00745 comGD 117786..118193 (+) 408 WP_011921721.1 competence type IV pilus minor pilin ComGD -
  VF946_RS00750 comYE 118165..118458 (+) 294 WP_011921722.1 competence type IV pilus minor pilin ComGE Machinery gene
  VF946_RS00755 comGF/cglF 118445..118879 (+) 435 WP_011922561.1 competence type IV pilus minor pilin ComGF Machinery gene
  VF946_RS00760 comGG 118857..119267 (+) 411 WP_011921724.1 competence type IV pilus minor pilin ComGG -
  VF946_RS00765 comYH 119324..120277 (+) 954 WP_024406069.1 class I SAM-dependent methyltransferase Machinery gene
  VF946_RS00770 - 120327..121514 (+) 1188 WP_012775473.1 acetate kinase -
  VF946_RS00775 - 121827..122378 (+) 552 WP_012775474.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38983.00 Da        Isoelectric Point: 9.3127

>NTDB_id=919738 VF946_RS00735 WP_256770774.1 116485..117522(+) (comYB) [Streptococcus suis strain HB18]
MRKLIGFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLIHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLSGLSLVAVLAGMVWFRKTNKIKVFSCLAALPFFGKLIQTYLTVYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=919738 VF946_RS00735 WP_256770774.1 116485..117522(+) (comYB) [Streptococcus suis strain HB18]
ATGCGCAAATTGATCGGCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTACCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCCAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGACGGGTTGCTGGCAGGCAAACCCTTTTCGAGTTTGCTG
GCAGATTTGCGATTTTCAGATGCGGTGGTCACACAGGTGGCTCTAGCAGAAGTTCATGGTAATACCAGCCTGAGTTTGAT
TCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCGATTATATTGC
TTGGTTTTCTGCTTTTGATTATGCTTGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCAGCGACAGTG
CTGATTAATCATCTACCGACCATCTTTTTATCTCTAAGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACCAATAAAATTAAGGTCTTTTCCTGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTACCTGA
CGGTCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCTTGATGCAAGAG
CAGCAGTCGCAGCTTTTTCGGGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGTTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTACGGTCAGGTCAAGTCCAAGTTGGGTAGCGAGT
TGACAGTTTATGCGGCTGAATGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTAATCCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.45

99.13

0.629
  comGB/cglB Streptococcus mitis NCTC 12261

60.597

97.101

0.588
  comGB/cglB Streptococcus mitis SK321

60.299

97.101

0.586
  comYB Streptococcus mutans UA140

59.238

98.841

0.586
  comYB Streptococcus mutans UA159

59.238

98.841

0.586
  comGB/cglB Streptococcus pneumoniae Rx1

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae D39

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae R6

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae TIGR4

60

97.101

0.583
  comGB Lactococcus lactis subsp. cremoris KW2

50.148

97.681

0.49