Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   SON02_RS05635 Genome accession   NZ_CP139211
Coordinates   1317772..1318722 (-) Length   316 a.a.
NCBI ID   WP_135027186.1    Uniprot ID   -
Organism   Streptococcus sp. LysM4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1312772..1323722
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SON02_RS05595 (SON02_05580) - 1312811..1314001 (-) 1191 WP_135027173.1 acetate kinase -
  SON02_RS05600 (SON02_05585) comYH 1314051..1315004 (-) 954 WP_135027174.1 class I SAM-dependent methyltransferase Machinery gene
  SON02_RS05605 (SON02_05590) comGG 1315027..1315422 (-) 396 WP_135027176.1 competence type IV pilus minor pilin ComGG -
  SON02_RS05610 (SON02_05595) comYF 1315433..1315867 (-) 435 WP_135027179.1 competence type IV pilus minor pilin ComGF Machinery gene
  SON02_RS05615 (SON02_05600) comGE 1315854..1316108 (-) 255 WP_228063764.1 competence type IV pilus minor pilin ComGE -
  SON02_RS05620 (SON02_05605) comGD 1316119..1316496 (-) 378 WP_373273837.1 competence type IV pilus minor pilin ComGD -
  SON02_RS05625 (SON02_05610) comGC/cglC 1316507..1316821 (-) 315 WP_135027183.1 competence type IV pilus major pilin ComGC Machinery gene
  SON02_RS05630 (SON02_05615) comYB 1316823..1317851 (-) 1029 WP_135027184.1 competence type IV pilus assembly protein ComGB Machinery gene
  SON02_RS05635 (SON02_05620) comGA/cglA/cilD 1317772..1318722 (-) 951 WP_135027186.1 competence type IV pilus ATPase ComGA Machinery gene
  SON02_RS05640 (SON02_05625) - 1318892..1319254 (-) 363 WP_135027188.1 DUF1033 family protein -
  SON02_RS05645 (SON02_05630) rpoC 1319762..1323397 (-) 3636 WP_135027190.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35548.57 Da        Isoelectric Point: 6.3091

>NTDB_id=908058 SON02_RS05635 WP_135027186.1 1317772..1318722(-) (comGA/cglA/cilD) [Streptococcus sp. LysM4]
MVQKIAQELIREAVAKGVSDLYLLPREASYQVYERVLDTRSLIGEFDESTYAAIISHFKFVAGMNVGEKRRSQQGACDYD
YKVGTIALRLSTVGDYRGKESLVIRFLYDQQEELHFWFDALDRVQDTIRGRGLYLFSGPVGSGKTTLMYHLAEMKFAEQQ
IVTIEDPVEIKRDAMLQLQLNETIGLTYDSLIKLSLRHRPDLLIIGEIRDKETARAVIRASLTGITIFSTVHGKSISGVY
ARMLELGVSSDELHHALQGIIYQRLIGGGGIVDVATEAYQTYSATQWNQQIDRLFTAGHISVRQAQAEKIIFDSSA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=908058 SON02_RS05635 WP_135027186.1 1317772..1318722(-) (comGA/cglA/cilD) [Streptococcus sp. LysM4]
ATGGTTCAAAAAATAGCGCAAGAACTGATTCGGGAAGCAGTAGCAAAAGGAGTAAGCGATCTTTATTTATTACCCCGAGA
AGCTTCTTACCAAGTCTATGAACGGGTATTGGATACTAGGAGTTTGATTGGTGAGTTTGATGAATCGACCTATGCTGCGA
TCATTAGTCATTTTAAATTTGTGGCAGGGATGAATGTTGGCGAAAAACGACGTAGCCAGCAAGGGGCATGTGATTATGAC
TATAAGGTAGGAACAATAGCGCTCAGACTGTCAACGGTTGGTGATTATCGTGGAAAAGAAAGTCTGGTAATTCGTTTCTT
GTACGATCAGCAAGAAGAATTGCATTTCTGGTTTGATGCCTTAGACCGTGTTCAAGACACGATAAGAGGACGGGGGCTGT
ATTTATTTTCAGGACCGGTAGGATCTGGTAAAACGACTCTGATGTATCATTTGGCAGAAATGAAATTCGCAGAACAACAG
ATTGTCACTATTGAGGATCCTGTCGAAATTAAGCGAGATGCGATGTTGCAATTACAACTCAATGAAACCATTGGTTTAAC
TTATGACAGCTTGATTAAACTATCTCTTCGGCATCGACCGGATTTACTGATTATTGGAGAAATTAGAGATAAGGAGACAG
CCCGAGCAGTTATTCGTGCTAGTTTGACAGGGATAACAATTTTTTCAACGGTTCATGGAAAAAGTATTTCAGGTGTCTAT
GCCCGCATGTTAGAGTTAGGAGTGAGTTCTGATGAATTGCACCATGCTTTACAGGGGATTATTTATCAACGTTTAATTGG
AGGAGGAGGAATTGTAGATGTGGCAACGGAAGCCTATCAAACCTATTCAGCAACGCAATGGAATCAGCAGATTGACAGAC
TTTTTACAGCAGGACATATCAGTGTTCGTCAAGCGCAGGCCGAAAAAATTATCTTTGACTCGTCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.064

98.734

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.744

98.734

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.744

98.734

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.744

98.734

0.639
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.744

98.734

0.639
  comYA Streptococcus gordonii str. Challis substr. CH1

64.839

98.101

0.636
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comYA Streptococcus mutans UA159

64.63

98.418

0.636
  comYA Streptococcus mutans UA140

64.63

98.418

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.459

100

0.538
  comGA Latilactobacillus sakei subsp. sakei 23K

42.491

86.392

0.367