Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   M2Z51_RS00180 Genome accession   NZ_AP024967
Coordinates   40087..41202 (+) Length   371 a.a.
NCBI ID   WP_032477164.1    Uniprot ID   -
Organism   Vibrio cholerae strain V130003     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 35087..46202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2Z51_RS00160 (V130003_00330) rsmB 36011..37291 (-) 1281 WP_001102805.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  M2Z51_RS00165 (V130003_00340) fmt 37347..38294 (-) 948 WP_032477162.1 methionyl-tRNA formyltransferase -
  M2Z51_RS00170 (V130003_00350) def 38302..38820 (-) 519 WP_129170461.1 peptide deformylase -
  M2Z51_RS00175 (V130003_00360) - 38960..40087 (+) 1128 WP_032477163.1 LysM peptidoglycan-binding domain-containing protein -
  M2Z51_RS00180 (V130003_00370) dprA 40087..41202 (+) 1116 WP_032477164.1 DNA-processing protein DprA Machinery gene
  M2Z51_RS00185 (V130003_00380) - 41205..41681 (+) 477 WP_000979769.1 DUF494 family protein -
  M2Z51_RS00190 (V130003_00390) - 41695..42261 (+) 567 WP_000087521.1 type I DNA topoisomerase -
  M2Z51_RS00195 (V130003_00400) - 42334..43467 (-) 1134 WP_032477166.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  M2Z51_RS00200 (V130003_00410) purE 43471..43956 (-) 486 WP_000215768.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  M2Z51_RS00205 (V130003_00420) - 44123..44680 (+) 558 WP_001911770.1 L-threonylcarbamoyladenylate synthase -
  M2Z51_RS00210 (V130003_00430) hemF 44699..45616 (+) 918 WP_000443976.1 oxygen-dependent coproporphyrinogen oxidase -

Sequence

Protein


Download         Length: 371 a.a.        Molecular weight: 39977.01 Da        Isoelectric Point: 7.1834

>NTDB_id=89776 M2Z51_RS00180 WP_032477164.1 40087..41202(+) (dprA) [Vibrio cholerae strain V130003]
MKDQDLAAWLALCFTPKLGSKTISHLLATRLPAQLQSFTPKQWLACGLKPEQLVFLTTQAAKQAEQCLLWRSAANNRYIV
TPHCPLYPRLLKEISSSPPILFIEGIWEAVHDPAVAIVGSRNASVDGRQIARQFATELAQSGLVVTSGLALGIDGYAHDG
ALQAQGQTVAVLGSGLAQVYPKQHQGLAERIIAQGALVSEFAPHTPPKADHFPRRNRIISGLSLGVVVVEAAEKSGSLIT
ARYAAEQGREVFVVPGSIFNAASQGSNQLIRQGACLVQSVQQIHQELKNALTWSLSEQVPYQATLFSAVQGDEELPFPEL
LANVGIEATPIDILASRTQIPVQDIMMQLLELELLGHVVAVPGGYIRKGRG

Nucleotide


Download         Length: 1116 bp        

>NTDB_id=89776 M2Z51_RS00180 WP_032477164.1 40087..41202(+) (dprA) [Vibrio cholerae strain V130003]
ATGAAAGATCAGGATTTAGCGGCATGGTTGGCGCTCTGTTTTACTCCTAAACTAGGCAGCAAAACCATTTCTCACCTGCT
TGCGACCCGTTTGCCAGCCCAGTTGCAAAGTTTTACGCCTAAGCAATGGTTGGCCTGCGGGCTTAAGCCCGAACAACTGG
TGTTTTTAACCACTCAAGCGGCTAAACAAGCCGAGCAGTGTTTGCTATGGCGATCAGCAGCCAATAACCGCTATATCGTC
ACTCCTCATTGCCCGCTTTACCCTCGTTTATTGAAAGAGATTAGCTCATCGCCTCCCATCCTGTTTATTGAAGGAATATG
GGAAGCGGTGCATGACCCTGCGGTGGCTATCGTCGGTAGCCGCAATGCCAGTGTTGATGGGCGGCAGATCGCTCGCCAGT
TTGCCACTGAGCTCGCGCAGTCGGGTTTAGTGGTCACCAGTGGTTTAGCGCTTGGTATTGATGGCTATGCGCACGATGGC
GCTTTGCAAGCACAAGGGCAAACCGTGGCAGTATTAGGCTCAGGGCTGGCGCAGGTTTACCCCAAACAGCATCAAGGGTT
AGCGGAGCGAATCATCGCCCAAGGGGCCTTGGTTTCTGAGTTTGCCCCTCACACACCTCCTAAAGCCGATCACTTTCCGC
GCCGTAACCGAATTATCAGCGGCTTATCGCTGGGCGTTGTGGTGGTAGAAGCTGCGGAGAAAAGCGGCTCACTCATCACT
GCGCGCTATGCCGCTGAGCAAGGGCGTGAGGTCTTTGTGGTTCCCGGCTCGATTTTTAATGCTGCCAGCCAAGGTAGCAA
TCAATTGATTCGTCAAGGCGCTTGTTTGGTGCAAAGTGTGCAACAAATTCATCAAGAGCTCAAAAATGCGCTGACTTGGT
CACTCTCTGAACAAGTTCCTTATCAAGCAACACTTTTTTCTGCTGTACAGGGCGATGAAGAATTGCCATTTCCCGAGCTG
TTAGCTAACGTAGGAATAGAAGCTACACCTATTGATATTCTCGCAAGTCGGACCCAGATACCGGTGCAAGATATCATGAT
GCAGCTCTTGGAGCTTGAGCTCCTTGGGCATGTGGTTGCAGTACCTGGTGGCTATATTAGAAAGGGGAGAGGCTAG

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(319-364)

DNA recombination-mediator protein A (DNA_processg_A)

(77-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio cholerae strain A1552

98.922

100

0.989
  dprA Vibrio campbellii strain DS40M4

58.108

99.73

0.58
  dprA Legionella pneumophila strain ERS1305867

43.583

100

0.439
  dprA Glaesserella parasuis strain SC1401

43.351

100

0.439
  dprA Neisseria meningitidis strain C311

37.594

100

0.404
  dprA Neisseria meningitidis MC58

37.594

100

0.404
  dprA Neisseria gonorrhoeae strain FA1090

36.658

100

0.396
  dprA Acinetobacter baumannii D1279779

43.807

89.218

0.391
  dprA Acinetobacter baumannii strain A118

43.505

89.218

0.388
  dprA Neisseria gonorrhoeae MS11

35.84

100

0.385
  dprA Acinetobacter baylyi ADP1

42.042

89.757

0.377
  dprA Haemophilus influenzae Rd KW20

48.746

75.202

0.367

Multiple sequence alignment