Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbB/cilA   Type   Machinery gene
Locus tag   R4702_RS07330 Genome accession   NZ_CP137106
Coordinates   1422054..1422449 (+) Length   131 a.a.
NCBI ID   WP_000282467.1    Uniprot ID   A0A098Z0L0
Organism   Streptococcus pneumoniae strain 16P4028     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1364782..1424214 1422054..1422449 within 0


Gene organization within MGE regions


Location: 1364782..1424214
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4702_RS06995 rpoC 1365988..1369665 (+) 3678 WP_000228766.1 DNA-directed RNA polymerase subunit beta' -
  R4702_RS07000 ndk 1369776..1370189 (+) 414 WP_000438285.1 nucleoside-diphosphate kinase -
  R4702_RS07005 - 1371117..1371749 (-) 633 WP_000571426.1 ABC transporter ATP-binding protein -
  R4702_RS07010 - 1371751..1373766 (-) 2016 WP_000732396.1 DUF1430 domain-containing protein -
  R4702_RS07015 - 1373911..1374081 (-) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  R4702_RS07020 - 1374270..1375133 (+) 864 WP_001093620.1 helix-turn-helix domain-containing protein -
  R4702_RS07025 comM 1375516..1376136 (+) 621 WP_000839909.1 hypothetical protein Regulator
  R4702_RS07030 tsaE 1376222..1376665 (+) 444 WP_000288230.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R4702_RS07035 - 1376655..1377173 (+) 519 WP_000455536.1 GNAT family N-acetyltransferase -
  R4702_RS07040 brpA 1377181..1378197 (+) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  R4702_RS07045 cinA 1378281..1379537 (+) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  R4702_RS07050 recA 1379592..1380758 (+) 1167 WP_001085463.1 recombinase RecA Machinery gene
  R4702_RS07055 - 1381069..1382439 (+) 1371 WP_317809564.1 MATE family efflux transporter -
  R4702_RS07060 lytA 1382815..1383771 (+) 957 WP_000405234.1 N-acetylmuramoyl-L-alanine amidase LytA -
  R4702_RS07065 - 1384433..1384747 (+) 315 WP_050205552.1 YdcP family protein -
  R4702_RS07070 - 1384763..1385149 (+) 387 WP_202484503.1 YdcP family protein -
  R4702_RS07075 - 1385189..1386583 (+) 1395 WP_317809573.1 FtsK/SpoIIIE domain-containing protein -
  R4702_RS07080 - 1386589..1387026 (+) 438 WP_015646595.1 hypothetical protein -
  R4702_RS07085 - 1387055..1387180 (+) 126 WP_075218791.1 conjugal transfer protein -
  R4702_RS07090 mobT 1387203..1388405 (+) 1203 Protein_1377 MobT family relaxase -
  R4702_RS07095 - 1388454..1388621 (+) 168 WP_000502600.1 MLS leader peptide -
  R4702_RS07100 - 1388670..1388753 (+) 84 WP_001814874.1 23S rRNA methyltransferase attenuation leader peptide -
  R4702_RS07105 erm(B) 1388878..1389615 (+) 738 WP_001038795.1 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) -
  R4702_RS07110 - 1389872..1391119 (-) 1248 WP_000019067.1 ISL3 family transposase -
  R4702_RS07115 - 1391299..1391520 (+) 222 WP_001009056.1 hypothetical protein -
  R4702_RS07120 - 1391637..1392134 (+) 498 WP_000342539.1 antirestriction protein ArdA -
  R4702_RS07125 - 1392223..1392615 (+) 393 WP_002345009.1 conjugal transfer protein -
  R4702_RS07130 - 1392599..1395046 (+) 2448 WP_050197513.1 ATP-binding protein -
  R4702_RS07135 - 1395049..1397226 (+) 2178 WP_000804748.1 CD3337/EF1877 family mobilome membrane protein -
  R4702_RS07140 - 1397223..1398224 (+) 1002 WP_000769868.1 lysozyme family protein -
  R4702_RS07145 - 1398221..1399153 (+) 933 WP_001224318.1 conjugal transfer protein -
  R4702_RS11005 - 1399467..1399514 (+) 48 Protein_1389 hypothetical protein -
  R4702_RS07155 tet(M) 1399530..1401449 (+) 1920 WP_044812736.1 tetracycline resistance ribosomal protection protein Tet(M) -
  R4702_RS07160 - 1401568..1401735 (+) 168 WP_000336323.1 cysteine-rich KTR domain-containing protein -
  R4702_RS07165 - 1401795..1402148 (-) 354 WP_001227347.1 helix-turn-helix transcriptional regulator -
  R4702_RS07170 - 1402653..1403075 (+) 423 WP_000804599.1 sigma-70 family RNA polymerase sigma factor -
  R4702_RS07175 - 1403072..1403302 (+) 231 WP_000857133.1 helix-turn-helix domain-containing protein -
  R4702_RS07180 - 1403527..1403775 (-) 249 Protein_1395 hypothetical protein -
  R4702_RS07185 - 1403759..1403962 (+) 204 WP_000814512.1 excisionase -
  R4702_RS07190 - 1404044..1405261 (+) 1218 WP_219590604.1 tyrosine-type recombinase/integrase -
  R4702_RS07195 - 1405484..1405645 (+) 162 WP_001055999.1 helix-turn-helix domain-containing protein -
  R4702_RS07200 - 1405632..1405838 (+) 207 WP_000366093.1 hypothetical protein -
  R4702_RS07205 - 1405884..1406240 (+) 357 Protein_1400 ImmA/IrrE family metallo-endopeptidase -
  R4702_RS07210 - 1406371..1406796 (+) 426 WP_000204059.1 hypothetical protein -
  R4702_RS07215 - 1407204..1407788 (+) 585 WP_001101199.1 hypothetical protein -
  R4702_RS07220 - 1407792..1407989 (+) 198 WP_000890144.1 hypothetical protein -
  R4702_RS07225 - 1407979..1408530 (+) 552 WP_001111259.1 hypothetical protein -
  R4702_RS07230 - 1408589..1408849 (+) 261 WP_001209200.1 hypothetical protein -
  R4702_RS07235 - 1409613..1409903 (-) 291 Protein_1406 transposase family protein -
  R4702_RS11010 - 1409881..1410012 (-) 132 WP_001821842.1 hypothetical protein -
  R4702_RS07240 - 1410137..1410595 (+) 459 WP_000186955.1 DUF4231 domain-containing protein -
  R4702_RS07245 - 1410608..1411216 (+) 609 WP_000083614.1 hypothetical protein -
  R4702_RS07250 - 1411209..1411619 (+) 411 WP_000595758.1 hypothetical protein -
  R4702_RS07255 ply 1411630..1413045 (+) 1416 WP_001284361.1 cholesterol-dependent cytolysin pneumolysin -
  R4702_RS07260 - 1413926..1414642 (+) 717 WP_000532876.1 YebC/PmpR family DNA-binding transcriptional regulator -
  R4702_RS07265 - 1414766..1415237 (+) 472 Protein_1413 MarR family winged helix-turn-helix transcriptional regulator -
  R4702_RS07270 - 1415254..1416075 (+) 822 Protein_1414 ABC transporter permease -
  R4702_RS07275 rcrQ 1416130..1417113 (+) 984 WP_224782081.1 ABC transporter ATP-binding protein/permease Regulator
  R4702_RS07280 - 1417179..1417541 (+) 363 WP_000078805.1 DUF2200 domain-containing protein -
  R4702_RS07285 - 1417538..1418041 (+) 504 WP_044789202.1 phosphatase PAP2 family protein -
  R4702_RS07290 - 1418155..1418601 (+) 447 WP_000776589.1 LytTR family DNA-binding domain-containing protein -
  R4702_RS07295 - 1418607..1419281 (+) 675 WP_050148694.1 LiaF transmembrane domain-containing protein -
  R4702_RS07300 - 1419442..1419633 (+) 192 WP_000291826.1 cell wall-binding protein -
  R4702_RS07305 - 1419658..1419720 (+) 63 WP_219300018.1 hypothetical protein -
  R4702_RS07310 - 1419918..1420217 (+) 300 WP_001013974.1 DUF4651 domain-containing protein -
  R4702_RS07315 - 1420214..1420531 (+) 318 WP_000615772.1 thioredoxin family protein -
  R4702_RS07320 ytpR 1420547..1421173 (+) 627 WP_000578289.1 YtpR family tRNA-binding protein -
  R4702_RS07325 - 1421215..1421976 (+) 762 WP_001107757.1 SDR family oxidoreductase -
  R4702_RS07330 ssbB/cilA 1422054..1422449 (+) 396 WP_000282467.1 single-stranded DNA-binding protein Machinery gene
  R4702_RS07335 groES 1422719..1423003 (+) 285 WP_000917339.1 co-chaperone GroES -

Sequence


Protein


Download         Length: 131 a.a.        Molecular weight: 14925.89 Da        Isoelectric Point: 5.9409

>NTDB_id=895581 R4702_RS07330 WP_000282467.1 1422054..1422449(+) (ssbB/cilA) [Streptococcus pneumoniae strain 16P4028]
MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGEREADFVNMVLWGRLAETLASYATKGSLISVDGELRTR
RFEKNGQMNYVTEVLVTGFQLLESRAQRAMRENNAGQDLADLVLEEEELPF

Nucleotide


Download         Length: 396 bp        

>NTDB_id=895581 R4702_RS07330 WP_000282467.1 1422054..1422449(+) (ssbB/cilA) [Streptococcus pneumoniae strain 16P4028]
ATGTATAATAAAGTTATCATGATTGGGCGTTTAACGTCTACACCAGAATTGCACAAAACCAACAATGACAAGTCGGTAGC
GCGAGCAACTATCGCTGTCAACCGTCGTTACAAAGACCAAAACGGTGAACGTGAAGCTGATTTTGTCAATATGGTCCTAT
GGGGCAGACTAGCAGAAACTTTGGCAAGCTACGCAACCAAAGGTAGTCTCATTTCCGTTGATGGAGAATTGCGTACCCGT
CGCTTTGAGAAAAATGGCCAAATGAACTACGTGACCGAAGTACTTGTAACAGGATTCCAACTCTTGGAAAGTCGTGCTCA
ACGTGCCATGCGTGAAAATAATGCAGGCCAAGATTTGGCAGATTTAGTCTTGGAAGAGGAAGAATTGCCATTTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A098Z0L0

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbB/cilA Streptococcus pneumoniae D39

100

100

1

  ssbB/cilA Streptococcus pneumoniae Rx1

100

100

1

  ssbB/cilA Streptococcus pneumoniae R6

100

100

1

  ssbB/cilA Streptococcus pneumoniae TIGR4

99.237

100

0.992

  ssbB/cilA Streptococcus mitis SK321

98.473

100

0.985

  ssbB/cilA Streptococcus mitis NCTC 12261

98.473

100

0.985

  ssbA Streptococcus mutans UA159

74.809

100

0.748

  ssbB Streptococcus sobrinus strain NIDR 6715-7

70.229

100

0.702

  ssbB Lactococcus lactis subsp. cremoris KW2

59.821

85.496

0.511

  ssbA Bacillus subtilis subsp. subtilis str. 168

50.943

80.916

0.412

  ssb Latilactobacillus sakei subsp. sakei 23K

46.903

86.26

0.405