Detailed information NTG0886510

Bioinformatically predicted

Overview

• Name: comE
• Type: Regulator
• Locus tag: RRU92_RS02085
• Genome accession: NZ_CP135436
• Coordinates: 417333..418085 (-)
• Length: 250 a.a.
• NCBI ID: WP_049530388.1
• Uniprot ID: -
• Organism: Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 412333..423085

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RRU92_RS02070 (RRU92_02070)	-	413571..416231 (-)	2661	WP_153224635.1	YhgE/Pip domain-containing protein	-
RRU92_RS02075 (RRU92_02075)	-	416362..416904 (+)	543	WP_061863863.1	TetR/AcrR family transcriptional regulator	-
RRU92_RS02085 (RRU92_02085)	comE	417333..418085 (-)	753	WP_049530388.1	competence system response regulator transcription factor ComE	Regulator
RRU92_RS02090 (RRU92_02090)	comD	418082..419401 (-)	1320	WP_315640220.1	competence system sensor histidine kinase ComD	Regulator
RRU92_RS02095 (RRU92_02095)	-	419424..419558 (-)	135	WP_315640221.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
RRU92_RS02105 (RRU92_02105)	rlmH	419841..420320 (-)	480	WP_153224633.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
RRU92_RS02110 (RRU92_02110)	htrA	420504..421688 (+)	1185	WP_315640222.1	S1C family serine protease	Regulator
RRU92_RS02115 (RRU92_02115)	spo0J	421745..422503 (+)	759	WP_153224631.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 250 a.a.
• Molecular weight: 29634.07 Da
• Isoelectric Point: 8.5500

>NTDB_id=886510 RRU92_RS02085 WP_049530388.1 417333..418085(-) (comE) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MKVLILEDIIEHQVRLETTLNKISKETNIPISYKTTGKVREFMEYVEHDEVNQLYFLDIDINGIERKGFEVAQFIRHRNP
YAIIVFITSRSEFATLTYKYKVSALDFIDKETSDQVFKNRVADCVLYTKTTLLENQSVVDYFDYSYKGNDLCIPYHDILY
IETTGTSHKLRIVGKNFAKEFYGTMTDIQEKDKETQRFYLAHKSFLVNIGNVREIDRKKMEVVFYEDHRCPISRLKTKKL
RELMAKNQKK

Nucleotide

• Length: 753 bp

>NTDB_id=886510 RRU92_RS02085 WP_049530388.1 417333..418085(-) (comE) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGAAAGTATTGATTTTAGAAGATATTATAGAACACCAAGTAAGGTTGGAAACAACTCTAAATAAAATTTCTAAGGAAAC
AAATATTCCTATCTCCTATAAAACAACAGGAAAAGTGAGAGAGTTTATGGAATATGTAGAGCATGATGAAGTCAATCAGC
TTTATTTTCTAGATATTGATATCAATGGGATTGAGAGAAAAGGATTTGAGGTTGCTCAATTTATTCGCCATCGCAATCCT
TATGCGATTATTGTTTTTATTACAAGTCGATCTGAATTTGCTACTTTGACTTATAAATACAAAGTTTCAGCATTGGATTT
CATTGATAAAGAAACCAGTGATCAAGTTTTTAAAAATAGAGTTGCCGACTGTGTGCTTTACACTAAGACTACTTTACTTG
AAAACCAATCAGTCGTTGATTATTTTGATTATAGTTATAAAGGAAATGATCTTTGTATTCCTTATCATGATATTCTCTAC
ATTGAAACAACGGGAACTTCTCATAAATTACGAATTGTAGGTAAGAATTTTGCCAAAGAATTCTATGGAACAATGACAGA
TATTCAAGAAAAGGATAAGGAAACCCAACGTTTTTATCTAGCTCACAAGTCATTTTTAGTCAATATCGGTAATGTGAGAG
AAATTGATCGTAAAAAAATGGAAGTTGTATTTTATGAAGATCATCGTTGTCCTATCTCTCGCCTAAAAACTAAAAAATTG
AGAGAACTAATGGCTAAAAACCAAAAAAAGTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-120)

• LytTr DNA-binding domain (LytTR) (152-244)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Streptococcus mitis NCTC 12261	79.6	100	0.796
comE	Streptococcus infantis strain Atu-4	79.2	100	0.792
comE	Streptococcus mitis SK321	79.2	100	0.792
comE	Streptococcus pneumoniae Rx1	79.2	100	0.792
comE	Streptococcus pneumoniae D39	79.2	100	0.792
comE	Streptococcus pneumoniae R6	79.2	100	0.792
comE	Streptococcus pneumoniae TIGR4	79.2	100	0.792
comE/comE2	Streptococcus gordonii strain NCTC7865	61.6	100	0.616
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	61.6	100	0.616
comE/blpR	Streptococcus mutans UA159	40.079	100	0.404