Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   RRU92_RS02090 Genome accession   NZ_CP135436
Coordinates   418082..419401 (-) Length   439 a.a.
NCBI ID   WP_315640220.1    Uniprot ID   -
Organism   Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 413082..424401
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RRU92_RS02070 (RRU92_02070) - 413571..416231 (-) 2661 WP_153224635.1 YhgE/Pip domain-containing protein -
  RRU92_RS02075 (RRU92_02075) - 416362..416904 (+) 543 WP_061863863.1 TetR/AcrR family transcriptional regulator -
  RRU92_RS02085 (RRU92_02085) comE 417333..418085 (-) 753 WP_049530388.1 competence system response regulator transcription factor ComE Regulator
  RRU92_RS02090 (RRU92_02090) comD 418082..419401 (-) 1320 WP_315640220.1 competence system sensor histidine kinase ComD Regulator
  RRU92_RS02095 (RRU92_02095) - 419424..419558 (-) 135 WP_315640221.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  RRU92_RS02105 (RRU92_02105) rlmH 419841..420320 (-) 480 WP_153224633.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  RRU92_RS02110 (RRU92_02110) htrA 420504..421688 (+) 1185 WP_315640222.1 S1C family serine protease Regulator
  RRU92_RS02115 (RRU92_02115) spo0J 421745..422503 (+) 759 WP_153224631.1 ParB/RepB/Spo0J family partition protein Regulator
  RRU92_RS02120 (RRU92_02120) dnaA 422725..424080 (+) 1356 WP_153224630.1 chromosomal replication initiator protein DnaA -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51158.83 Da        Isoelectric Point: 7.2174

>NTDB_id=886511 RRU92_RS02090 WP_315640220.1 418082..419401(-) (comD) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MDLFGLVIAIVYVFIISKIHEWVCKATRKDQYFFSLYIFLLPLVLEVTLHFLNLDSFGLSKFLFPFLLFGYFVGFKKYEK
SKGIFISLLFSLLYNSTNNFLSVTLSSITGDEFALKYNNYFSLFILILTYLVIKVVVSYFHLEFKYFDKDYLYPFLKKVL
FTFIFLHVVSFTSDIVSTIRHLNGFGSILSSIIFVGLLLTFFSMNSHKVQIEKEIELEQKKFEQKHLQTYTDEIVTLYNE
IRGFRHDYTGMLISLRMAIESKDLQEIDRVYSEVLVKANQKLRSDKYTYFDLNNIEDSALRSLIAQSIVNAKTNDVEYTL
EVKDIITPLSMELLDLVRVMSVLLNNAVEGAVESYQKQLEVAIIKLDLETLVVIQNSCKKRKVKSEDLFELGFSTKGRHR
GLGLNNVKEILGKYDNVILETEIDNDVFKQVIRFKRELI

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=886511 RRU92_RS02090 WP_315640220.1 418082..419401(-) (comD) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGGATTTATTCGGATTAGTAATTGCTATTGTTTATGTTTTTATTATTAGTAAAATTCATGAATGGGTTTGTAAAGCAAC
TAGAAAAGACCAATATTTTTTTAGTCTTTATATCTTTCTACTACCATTAGTATTAGAAGTAACTCTCCATTTCTTGAACT
TAGATAGTTTTGGTTTGTCTAAATTTTTATTTCCTTTCCTCCTATTTGGTTACTTTGTTGGATTTAAGAAGTATGAGAAA
TCTAAGGGAATTTTTATCAGTCTATTATTTTCTCTTTTATATAATAGTACTAATAACTTTTTATCGGTAACCTTATCATC
TATTACAGGAGATGAGTTTGCATTGAAGTATAACAATTATTTTTCTCTATTTATCCTGATCTTAACTTATTTGGTTATTA
AAGTTGTTGTTTCTTATTTCCATCTCGAATTTAAATATTTTGATAAAGACTATCTATATCCTTTTCTGAAAAAAGTGCTC
TTTACATTTATTTTTCTACACGTTGTCTCTTTCACTTCAGATATTGTGAGTACGATTCGTCACTTAAATGGTTTTGGAAG
TATTTTATCATCCATTATTTTTGTTGGCCTACTTTTGACTTTCTTTTCTATGAATTCTCACAAGGTTCAGATAGAAAAAG
AGATTGAATTGGAACAAAAGAAGTTTGAGCAAAAACATTTACAAACTTACACGGATGAGATTGTTACTTTATATAATGAA
ATTCGTGGTTTTCGTCATGATTATACAGGCATGCTTATCAGCTTAAGAATGGCGATTGAAAGTAAAGATTTACAAGAGAT
TGACAGAGTTTACAGTGAAGTTCTTGTCAAAGCAAATCAAAAATTACGTTCAGATAAGTATACCTATTTCGATTTGAACA
ATATTGAGGACTCAGCGCTTCGAAGTTTGATTGCCCAATCTATTGTCAATGCGAAAACTAATGATGTAGAGTACACATTA
GAGGTAAAAGATATTATTACACCTTTATCTATGGAATTGTTAGATTTGGTGCGCGTGATGAGCGTTCTGCTCAATAATGC
TGTTGAAGGGGCAGTTGAAAGCTATCAAAAACAACTAGAGGTAGCTATCATCAAGTTGGATCTTGAAACCCTAGTTGTCA
TCCAAAACTCTTGTAAAAAAAGAAAGGTAAAATCCGAAGATTTATTTGAATTAGGATTTTCAACTAAAGGAAGACATAGA
GGACTTGGACTTAATAATGTTAAAGAAATTTTAGGAAAATATGACAATGTTATTTTAGAAACAGAAATTGATAATGATGT
ATTTAAACAAGTAATTAGATTTAAGAGGGAACTGATATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(331-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis NCTC 12261

67.198

100

0.672
  comD Streptococcus mitis SK321

66.743

100

0.667
  comD/comD2 Streptococcus pneumoniae TIGR4

66.059

100

0.661
  comD/comD1 Streptococcus pneumoniae R6

65.831

100

0.658
  comD/comD1 Streptococcus pneumoniae Rx1

65.831

100

0.658
  comD/comD1 Streptococcus pneumoniae D39

65.831

100

0.658
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

48.413

86.105

0.417
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.67

85.649

0.417