Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   RIM64_RS00690 Genome accession   NZ_CP133951
Coordinates   118083..119021 (+) Length   312 a.a.
NCBI ID   WP_012677233.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain JMC111     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 113083..124021
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIM64_RS00670 (RIM64_00670) - 113234..114280 (+) 1047 WP_207622529.1 acyltransferase family protein -
  RIM64_RS00675 (RIM64_00675) - 114341..114706 (+) 366 WP_165619319.1 DUF1033 family protein -
  RIM64_RS00680 (RIM64_00680) - 115251..117254 (+) 2004 WP_012677231.1 DUF1430 domain-containing protein -
  RIM64_RS00685 (RIM64_00685) - 117256..117903 (+) 648 WP_012677232.1 ATP-binding cassette domain-containing protein -
  RIM64_RS00690 (RIM64_00690) comGA/cglA 118083..119021 (+) 939 WP_012677233.1 competence type IV pilus ATPase ComGA Machinery gene
  RIM64_RS00695 (RIM64_00695) comYB 118954..119988 (+) 1035 WP_228273970.1 competence type IV pilus assembly protein ComGB Machinery gene
  RIM64_RS00700 (RIM64_00700) comGC/cglC 119989..120312 (+) 324 WP_012677235.1 competence type IV pilus major pilin ComGC Machinery gene
  RIM64_RS00705 (RIM64_00705) comGD 120290..120715 (+) 426 WP_012514783.1 competence type IV pilus minor pilin ComGD -
  RIM64_RS00710 (RIM64_00710) comGE 120720..120962 (+) 243 WP_012677236.1 competence type IV pilus minor pilin ComGE -
  RIM64_RS00715 (RIM64_00715) comYF 120949..121383 (+) 435 WP_115266549.1 competence type IV pilus minor pilin ComGF Machinery gene
  RIM64_RS00720 (RIM64_00720) comGG 121361..121723 (+) 363 WP_115266550.1 competence type IV pilus minor pilin ComGG -
  RIM64_RS00725 (RIM64_00725) comYH 121785..122738 (+) 954 WP_165619320.1 class I SAM-dependent methyltransferase Machinery gene
  RIM64_RS00730 (RIM64_00730) - 122798..124000 (+) 1203 WP_115266552.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35248.56 Da        Isoelectric Point: 7.0749

>NTDB_id=877678 RIM64_RS00690 WP_012677233.1 118083..119021(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain JMC111]
MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDGVKVSLRLSAVGDYQGQESLVIRLLYHCRRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQASQWNQQIDQLLAEGHLNTKQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=877678 RIM64_RS00690 WP_012677233.1 118083..119021(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain JMC111]
ATGATTCAAGAATTAGCCAAGCGGCTTATCAGGCAGGCTGAAGAATTGCAGGCTCAGGATATTTATATACTACCAAGGGG
GACAGGCTATGAGCTTTTGATGAGGGTAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGCGAAAAAAGACGCTGCCAGCTCGGTGCTTGTGACTACGAC
CTTGATGGCGTTAAGGTGTCTCTACGATTATCAGCTGTGGGTGATTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATTGTCGACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCTAGAGGCCTTT
ACCTCTTTTCTGGACCAGTCGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATAAAAAATGACCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTCTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATTAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAGCCAGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATACCAAGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.065

99.359

0.676
  comYA Streptococcus mutans UA159

63.023

99.679

0.628
  comYA Streptococcus mutans UA140

63.023

99.679

0.628
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.29

99.359

0.609
  comYA Streptococcus gordonii str. Challis substr. CH1

60.968

99.359

0.606
  comGA Lactococcus lactis subsp. cremoris KW2

52.733

99.679

0.526
  comGA Latilactobacillus sakei subsp. sakei 23K

40.273

93.91

0.378