Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   V8N34_RS00760 Genome accession   NZ_CP149804
Coordinates   117952..118902 (+) Length   316 a.a.
NCBI ID   WP_002936562.1    Uniprot ID   -
Organism   Streptococcus suis strain YA     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 112952..123902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V8N34_RS00750 (V8N34_00750) - 116516..116881 (+) 366 WP_002936568.1 DUF1033 family protein -
  V8N34_RS00755 (V8N34_00755) - 116916..117866 (-) 951 WP_014636751.1 S66 peptidase family protein -
  V8N34_RS00760 (V8N34_00760) comGA 117952..118902 (+) 951 WP_002936562.1 competence type IV pilus ATPase ComGA Machinery gene
  V8N34_RS00765 (V8N34_00765) comGB 118814..119851 (+) 1038 WP_255195823.1 competence type IV pilus assembly protein ComGB Machinery gene
  V8N34_RS00770 (V8N34_00770) comGC 119853..120134 (+) 282 WP_002936550.1 competence type IV pilus major pilin ComGC Machinery gene
  V8N34_RS00775 (V8N34_00775) comGD/cglD 120115..120522 (+) 408 WP_318825439.1 competence type IV pilus minor pilin ComGD Machinery gene
  V8N34_RS00780 (V8N34_00780) comGE 120494..120787 (+) 294 WP_002936548.1 competence type IV pilus minor pilin ComGE Machinery gene
  V8N34_RS00785 (V8N34_00785) comGF/cglF 120774..121208 (+) 435 WP_002936547.1 competence type IV pilus minor pilin ComGF Machinery gene
  V8N34_RS00790 (V8N34_00790) comGG 121186..121596 (+) 411 WP_002936546.1 competence type IV pilus minor pilin ComGG -
  V8N34_RS00795 (V8N34_00795) comGH 121653..122606 (+) 954 WP_044668119.1 class I SAM-dependent methyltransferase Machinery gene
  V8N34_RS00800 (V8N34_00800) - 122656..123843 (+) 1188 WP_002936543.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35490.39 Da        Isoelectric Point: 6.1802

>NTDB_id=875447 V8N34_RS00760 WP_002936562.1 117952..118902(+) (comGA) [Streptococcus suis strain YA]
MIQEKARKLIEKAVADRVSDIYLVPRGESYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIRGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=875447 V8N34_RS00760 WP_002936562.1 117952..118902(+) (comGA) [Streptococcus suis strain YA]
ATGATTCAAGAAAAAGCAAGAAAGTTGATTGAAAAGGCAGTGGCGGATAGGGTCAGTGACATTTATCTGGTTCCTCGCGG
GGAAAGCTATCAAGTTTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTCTGGTGATCCGCTTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCTGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGTCTGACAGGAGCGACGGTCTTCTCAACGGTTCACGCAAGGTCTATTTCGGGTGTCTAT
GCTCGTATGTTGGAATTGGGGGTCAGTCCTGAGGAGTTAAACAATGCCCTTCAAGGTATTGCCTATCAACGTTTAATCAG
GGGAGGAGGTGTGGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Streptococcus gordonii str. Challis substr. CH1

68.387

98.101

0.671
  comGA Streptococcus mutans UA159

67.524

98.418

0.665
  comGA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.943

100

0.541
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364