Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7586_RS21985 Genome accession   NZ_CP131791
Coordinates   4703788..4705005 (-) Length   405 a.a.
NCBI ID   WP_033944807.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain 2014S05-249     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4698788..4710005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7586_RS21940 (Q7586_21945) - 4698970..4699419 (-) 450 WP_003094670.1 MOSC domain-containing protein -
  Q7586_RS21945 (Q7586_21950) - 4699416..4700045 (-) 630 WP_003094668.1 DUF1780 domain-containing protein -
  Q7586_RS21950 (Q7586_21955) - 4700178..4700603 (+) 426 WP_016562341.1 GNAT family N-acetyltransferase -
  Q7586_RS21955 (Q7586_21960) - 4700600..4701070 (+) 471 WP_003094664.1 hypothetical protein -
  Q7586_RS21960 (Q7586_21965) - 4701067..4701756 (+) 690 WP_003103868.1 energy-coupling factor ABC transporter permease -
  Q7586_RS21965 (Q7586_21970) - 4701862..4702071 (+) 210 WP_003094660.1 hypothetical protein -
  Q7586_RS21970 (Q7586_21975) yacG 4702108..4702308 (-) 201 WP_003094656.1 DNA gyrase inhibitor YacG -
  Q7586_RS21975 (Q7586_21980) coaE 4702305..4702916 (-) 612 WP_003112838.1 dephospho-CoA kinase -
  Q7586_RS21980 (Q7586_21985) pilD 4702913..4703785 (-) 873 WP_033944809.1 type IV prepilin peptidase/methyltransferase PilD Machinery gene
  Q7586_RS21985 (Q7586_21990) pilC 4703788..4705005 (-) 1218 WP_033944807.1 type II secretion system F family protein Machinery gene
  Q7586_RS21990 (Q7586_21995) pilB 4705009..4706712 (-) 1704 WP_033944805.1 type IV-A pilus assembly ATPase PilB Machinery gene
  Q7586_RS21995 (Q7586_22000) pilE 4706939..4707475 (+) 537 WP_025921208.1 pilin Machinery gene
  Q7586_RS22000 (Q7586_22005) tfpZ 4707540..4708277 (+) 738 WP_023100229.1 TfpX/TfpZ family type IV pilin accessory protein -
  Q7586_RS22010 (Q7586_22015) nadC 4708511..4709359 (-) 849 WP_003125200.1 carboxylating nicotinate-nucleotide diphosphorylase -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 43845.84 Da        Isoelectric Point: 9.9457

>NTDB_id=865182 Q7586_RS21985 WP_033944807.1 4703788..4705005(-) (pilC) [Pseudomonas aeruginosa strain 2014S05-249]
MADKALKTSVFIWEGTDKKGSKVKGELTGQNPMLVKAQLRKQGINPLKVRKKGITLFGAGKKIKPMDIALFTRQMATMMG
AGVPLLQSFDIIGEGFENPNMRKLVDEIKQEVAAGNSLANSLRKKPQYFDDLYCNLVDAGEQSGALETLLARVATYKEKT
EALKAKIKKAMTYPIAVVIVALVVSAILLIKVVPQFQSVFANFGAELPAFTQMVIGLSETLQEWWLLVLIAMLGIGFALK
ELYKRSKGFRDTIDRAILKAPIVGAIVYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFKSAVAKIKQDVSSGM
QLNFSMRTTNVFPSMAIQMAAIGEESGSLDDMLGKVAGFYEDEVDNAVDNLTTLMEPMIMAVLGVLVGGLIVAMYLPIFQ
LGKVI

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=865182 Q7586_RS21985 WP_033944807.1 4703788..4705005(-) (pilC) [Pseudomonas aeruginosa strain 2014S05-249]
ATGGCGGACAAAGCGTTAAAGACCAGTGTCTTCATCTGGGAAGGTACTGATAAGAAGGGCAGCAAGGTCAAAGGAGAGTT
GACCGGGCAAAACCCTATGCTGGTCAAAGCCCAGCTACGCAAACAGGGTATCAATCCGCTGAAAGTCCGCAAGAAAGGCA
TCACGCTATTCGGTGCGGGAAAAAAAATCAAACCCATGGACATCGCACTGTTCACTCGGCAGATGGCGACCATGATGGGC
GCAGGCGTGCCCCTATTGCAGTCCTTCGACATCATTGGCGAGGGTTTCGAAAATCCGAACATGCGAAAGCTGGTTGACGA
AATAAAGCAGGAAGTCGCAGCCGGTAATAGCTTGGCCAACTCACTACGAAAGAAGCCCCAGTATTTTGACGACCTTTACT
GCAATCTTGTAGATGCGGGCGAACAATCAGGCGCATTGGAAACGCTTCTCGCCCGGGTTGCTACCTACAAGGAAAAAACT
GAGGCACTCAAAGCCAAGATCAAGAAAGCTATGACCTACCCTATCGCGGTCGTTATCGTGGCACTGGTGGTCTCTGCGAT
CCTACTCATTAAGGTTGTTCCGCAATTCCAGTCAGTTTTCGCGAACTTTGGTGCAGAGCTACCAGCCTTCACTCAAATGG
TGATCGGACTTTCGGAAACATTACAAGAATGGTGGCTACTTGTCCTCATCGCCATGCTCGGCATAGGTTTTGCTCTGAAA
GAGTTGTACAAGCGCTCCAAAGGTTTCCGCGACACCATAGACAGAGCCATACTGAAAGCTCCCATCGTCGGTGCCATCGT
CTATAAGTCAGCCGTAGCACGTTATGCACGGACCCTATCGACTACGTTTGCAGCAGGCGTTCCTCTAGTCGAGGCTTTGG
ATTCGGTATCAGGGGCCACAGGTAATGTGGTGTTTAAAAGCGCAGTCGCCAAGATCAAGCAGGACGTTTCCAGCGGTATG
CAGTTGAACTTCTCCATGCGCACCACCAATGTTTTTCCGAGTATGGCTATCCAGATGGCTGCGATTGGCGAAGAATCTGG
TTCGCTGGACGACATGCTTGGCAAAGTGGCTGGCTTCTACGAGGATGAAGTAGATAATGCCGTCGACAATTTGACGACTT
TGATGGAACCAATGATCATGGCGGTGCTAGGAGTCCTGGTTGGCGGATTGATCGTCGCTATGTATCTGCCTATTTTCCAG
CTCGGCAAAGTTATCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

79.506

100

0.795
  pilC Acinetobacter baylyi ADP1

58.968

100

0.593
  pilC Acinetobacter baumannii D1279779

59.158

99.753

0.59
  pilC Legionella pneumophila strain ERS1305867

53.535

97.778

0.523
  pilG Neisseria meningitidis 44/76-A

45.926

100

0.459
  pilG Neisseria gonorrhoeae MS11

45.679

100

0.457
  pilC Vibrio cholerae strain A1552

42.963

100

0.43
  pilC Vibrio campbellii strain DS40M4

41.162

97.778

0.402
  pilC Thermus thermophilus HB27

37.656

99.012

0.373