Detailed information NTG0853878

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: V6U68_RS08385
• Genome accession: NZ_CP145866
• Coordinates: 1820899..1821639 (+)
• Length: 246 a.a.
• NCBI ID: WP_410531625.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS9
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1815899..1826639

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U68_RS08360 (V6U68_08340)	gla	1815965..1816831 (-)	867	WP_037602504.1	aquaglyceroporin Gla	-
V6U68_RS08365 (V6U68_08345)	-	1816952..1819219 (+)	2268	WP_073687330.1	Xaa-Pro dipeptidyl-peptidase	-
V6U68_RS08370 (V6U68_08350)	-	1819419..1819715 (-)	297	WP_073687331.1	bacteriocin immunity protein	-
V6U68_RS08375 (V6U68_08355)	-	1820083..1820475 (-)	393	WP_003094909.1	hypothetical protein	-
V6U68_RS08380 (V6U68_08360)	-	1820511..1820645 (-)	135	Protein_1611	Blp family class II bacteriocin	-
V6U68_RS08385 (V6U68_08365)	comE/blpR	1820899..1821639 (+)	741	WP_410531625.1	response regulator transcription factor	Regulator
V6U68_RS08390 (V6U68_08370)	comD/comD3	1822221..1822970 (+)	750	WP_014634988.1	sensor histidine kinase	Regulator
V6U68_RS08395 (V6U68_08375)	-	1823057..1823458 (-)	402	WP_038676702.1	hypothetical protein	-
V6U68_RS08400 (V6U68_08380)	-	1824431..1824661 (-)	231	WP_014632652.1	Blp family class II bacteriocin	-
V6U68_RS08405 (V6U68_08385)	-	1824822..1826570 (-)	1749	WP_410531627.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28676.32 Da
• Isoelectric Point: 9.1797

>NTDB_id=853878 V6U68_RS08385 WP_410531625.1 1820899..1821639(+) (comE/blpR) [Streptococcus salivarius strain KSS9]
MDIYILEDNLIQQGRLEMVLSQELKKYNKDLSIVHTFDKPQQFIEAIDSTTSNQLFFLDIKIKGEKLKGLDIAKIIREKN
PYATIIFVTTHSEFMPLVFDYQVSALDYIDKSLSEIEFRKKITRALAITMKPLGIENDEIFDFQTQHTAIRIPLNQVIYI
ETSPQKHYVILHGTNNQMTFRANLKDLEKASPSLVSCHRSYLINPNNIIRINKLKREVEMTDGSICPFSRTKAKMLMDTF
KRRNLQ

Nucleotide

• Length: 741 bp

>NTDB_id=853878 V6U68_RS08385 WP_410531625.1 1820899..1821639(+) (comE/blpR) [Streptococcus salivarius strain KSS9]
TTGGATATATATATCTTAGAGGACAATCTCATTCAACAAGGACGACTGGAGATGGTATTGTCTCAAGAGTTAAAAAAATA
CAATAAAGACTTATCTATTGTACACACCTTTGATAAGCCTCAGCAATTTATAGAAGCGATTGATTCAACAACTTCTAACC
AGCTCTTTTTTCTTGATATCAAAATTAAGGGAGAAAAATTAAAAGGGCTCGATATTGCTAAAATCATTAGGGAAAAAAAT
CCCTACGCTACTATTATCTTTGTCACTACCCACTCAGAGTTTATGCCACTAGTTTTTGATTACCAAGTATCTGCCCTAGA
CTATATTGATAAAAGTCTCTCTGAAATAGAATTTAGGAAAAAGATAACCAGAGCTTTAGCTATAACTATGAAACCACTTG
GAATAGAGAATGACGAGATTTTTGATTTTCAAACACAACATACAGCTATTCGCATACCTTTAAACCAAGTTATCTATATT
GAAACTTCTCCGCAAAAGCATTATGTGATACTCCATGGTACAAACAATCAAATGACCTTTCGTGCAAATCTAAAGGACCT
TGAAAAAGCTAGTCCTTCACTCGTATCTTGCCATCGTTCGTATCTCATTAACCCTAACAACATTATAAGAATCAACAAAT
TAAAACGTGAAGTCGAAATGACTGATGGTAGTATCTGTCCTTTTTCACGTACCAAAGCTAAAATGCTGATGGATACTTTT
AAAAGAAGGAACCTTCAATGA

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (150-239)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	43.162	95.122	0.411
comE/comE2	Streptococcus equinus JB1	39.241	96.341	0.378
comE/comE2	Streptococcus gordonii strain NCTC7865	37.2	100	0.378
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.2	100	0.378
comE/comE1	Streptococcus equinus JB1	38.235	96.748	0.37
comE	Streptococcus pneumoniae TIGR4	35.6	100	0.362
comE	Streptococcus mitis SK321	35.6	100	0.362
comE	Streptococcus mitis NCTC 12261	35.6	100	0.362
comE	Streptococcus infantis strain Atu-4	35.6	100	0.362
comE	Streptococcus pneumoniae Rx1	35.6	100	0.362
comE	Streptococcus pneumoniae D39	35.6	100	0.362
comE	Streptococcus pneumoniae R6	35.6	100	0.362