Detailed information NTG0840760

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: F6I26_RS01150
• Genome accession: NZ_CP126961
• Coordinates: 207369..207686 (+)
• Length: 105 a.a.
• NCBI ID: WP_003028473.1
• Uniprot ID: A0A0P0N5S2
• Organism: Streptococcus anginosus strain UMB4708
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 202369..212686

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F6I26_RS01120 (F6I26_001120)	-	202494..203024 (+)	531	WP_070241503.1	aromatic acid exporter family protein	-
F6I26_RS01125 (F6I26_001125)	-	203101..203460 (+)	360	WP_003070793.1	MerR family transcriptional regulator	-
F6I26_RS01130 (F6I26_001130)	glnA	203498..204844 (+)	1347	WP_024053132.1	type I glutamate--ammonia ligase	-
F6I26_RS01135 (F6I26_001135)	-	205032..205397 (+)	366	WP_024053131.1	DUF1033 family protein	-
F6I26_RS01140 (F6I26_001140)	comYA	205467..206408 (+)	942	WP_024053130.1	competence type IV pilus ATPase ComGA	Machinery gene
F6I26_RS01145 (F6I26_001145)	comYB	206350..207372 (+)	1023	WP_171021869.1	competence type IV pilus assembly protein ComGB	Machinery gene
F6I26_RS01150 (F6I26_001150)	comYC	207369..207686 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
F6I26_RS01155 (F6I26_001155)	comYD	207676..208074 (+)	399	WP_022525973.1	competence type IV pilus minor pilin ComGD	Machinery gene
F6I26_RS01160 (F6I26_001160)	comGE/cglE	208046..208339 (+)	294	WP_024053127.1	competence type IV pilus minor pilin ComGE	Machinery gene
F6I26_RS01165 (F6I26_001165)	comGF/cglF	208323..208760 (+)	438	WP_024053126.1	competence type IV pilus minor pilin ComGF	Machinery gene
F6I26_RS01170 (F6I26_001170)	comGG	208741..209067 (+)	327	WP_257360478.1	competence type IV pilus minor pilin ComGG	-
F6I26_RS01175 (F6I26_001175)	comYH	209139..210092 (+)	954	WP_024053125.1	class I SAM-dependent methyltransferase	Machinery gene
F6I26_RS01180 (F6I26_001180)	-	210139..211338 (+)	1200	WP_024053124.1	acetate kinase	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11622.72 Da
• Isoelectric Point: 10.1006

>NTDB_id=840760 F6I26_RS01150 WP_003028473.1 207369..207686(+) (comYC) [Streptococcus anginosus strain UMB4708]
MKKLKSLKVKGFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVNEGT
ITDKQAASYKAYYAKHTKEARSVAD

Nucleotide

• Length: 318 bp

>NTDB_id=840760 F6I26_RS01150 WP_003028473.1 207369..207686(+) (comYC) [Streptococcus anginosus strain UMB4708]
ATGAAAAAATTAAAAAGTTTGAAGGTTAAAGGTTTTACTTTAGTAGAAATGTTAGTCGTGCTTCTTATCATCAGTGTTTT
GATGCTCTTATTTGTACCGAATTTGACCAAGCAAAAAGAAGCTGTAACGGAAAAAGGAAATGCAGCGGTGGTAAAAGTTG
TGGAAAGCCAGGCAGAGCTGTTTGAGGTCAATCACACCAATGAAAAAGCGACACTCTCAAAATTAGTCAACGAAGGAACG
ATTACAGACAAGCAGGCAGCATCTTATAAGGCTTACTATGCGAAACATACAAAAGAAGCTCGTTCTGTTGCAGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0P0N5S2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	73.333	100	0.733
comYC	Streptococcus mutans UA159	66.667	100	0.667
comYC	Streptococcus mutans UA140	66.667	100	0.667
comGC/cglC	Streptococcus mitis NCTC 12261	68.627	97.143	0.667
comGC/cglC	Streptococcus mitis SK321	68.627	97.143	0.667
comGC/cglC	Streptococcus pneumoniae R6	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae D39	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae Rx1	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae TIGR4	66.667	97.143	0.648
comYC	Streptococcus suis isolate S10	66.292	84.762	0.562
comGC	Lactococcus lactis subsp. cremoris KW2	54.808	99.048	0.543