Detailed information NTG0840763

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: F6I26_RS01165
• Genome accession: NZ_CP126961
• Coordinates: 208323..208760 (+)
• Length: 145 a.a.
• NCBI ID: WP_024053126.1
• Uniprot ID: A0A413KLZ8
• Organism: Streptococcus anginosus strain UMB4708
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 203323..213760

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F6I26_RS01130 (F6I26_001130)	glnA	203498..204844 (+)	1347	WP_024053132.1	type I glutamate--ammonia ligase	-
F6I26_RS01135 (F6I26_001135)	-	205032..205397 (+)	366	WP_024053131.1	DUF1033 family protein	-
F6I26_RS01140 (F6I26_001140)	comYA	205467..206408 (+)	942	WP_024053130.1	competence type IV pilus ATPase ComGA	Machinery gene
F6I26_RS01145 (F6I26_001145)	comYB	206350..207372 (+)	1023	WP_171021869.1	competence type IV pilus assembly protein ComGB	Machinery gene
F6I26_RS01150 (F6I26_001150)	comYC	207369..207686 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
F6I26_RS01155 (F6I26_001155)	comYD	207676..208074 (+)	399	WP_022525973.1	competence type IV pilus minor pilin ComGD	Machinery gene
F6I26_RS01160 (F6I26_001160)	comGE/cglE	208046..208339 (+)	294	WP_024053127.1	competence type IV pilus minor pilin ComGE	Machinery gene
F6I26_RS01165 (F6I26_001165)	comGF/cglF	208323..208760 (+)	438	WP_024053126.1	competence type IV pilus minor pilin ComGF	Machinery gene
F6I26_RS01170 (F6I26_001170)	comGG	208741..209067 (+)	327	WP_257360478.1	competence type IV pilus minor pilin ComGG	-
F6I26_RS01175 (F6I26_001175)	comYH	209139..210092 (+)	954	WP_024053125.1	class I SAM-dependent methyltransferase	Machinery gene
F6I26_RS01180 (F6I26_001180)	-	210139..211338 (+)	1200	WP_024053124.1	acetate kinase	-
F6I26_RS01185 (F6I26_001185)	glmS	211739..213553 (+)	1815	WP_024053123.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16883.44 Da
• Isoelectric Point: 10.0408

>NTDB_id=840763 F6I26_RS01165 WP_024053126.1 208323..208760(+) (comGF/cglF) [Streptococcus anginosus strain UMB4708]
MFKANKVKAFTLLEALIVLFVLSGSVLLFQSMTRLLAFEVQARQHSEQREWLLFADQLEAELARSSFEKVENNRLYMKQD
GRAIAFGKSSGQDFRKTNANGKGYQPMVYDVKKAEISQKNELIYVRLTFRRGLEREFVYRVETES

Nucleotide

• Length: 438 bp

>NTDB_id=840763 F6I26_RS01165 WP_024053126.1 208323..208760(+) (comGF/cglF) [Streptococcus anginosus strain UMB4708]
GTGTTCAAGGCAAATAAAGTGAAAGCTTTTACCCTTTTAGAGGCTCTGATTGTCTTATTTGTACTCAGCGGAAGTGTGCT
GCTTTTTCAGTCAATGACGCGTCTTCTGGCTTTTGAAGTTCAAGCCCGGCAACATAGTGAACAACGAGAATGGCTTTTGT
TTGCTGATCAACTAGAAGCAGAGTTGGCTCGTTCTTCATTTGAAAAGGTGGAGAATAATCGTTTATATATGAAACAGGAC
GGCAGGGCAATTGCATTTGGAAAGTCAAGTGGACAGGATTTCAGAAAAACCAATGCGAATGGGAAAGGTTACCAGCCGAT
GGTTTATGATGTAAAAAAAGCAGAAATCTCACAGAAAAATGAGCTGATTTATGTTAGACTGACGTTTAGGCGAGGATTGG
AAAGGGAGTTTGTCTATCGTGTGGAAACAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

3D structure

• AlphaFold DB: A0A413KLZ8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae R6	64.085	97.931	0.628
comGF/cglF	Streptococcus pneumoniae TIGR4	64.085	97.931	0.628
comGF/cglF	Streptococcus pneumoniae Rx1	64.085	97.931	0.628
comGF/cglF	Streptococcus pneumoniae D39	64.085	97.931	0.628
comGF/cglF	Streptococcus mitis NCTC 12261	64.286	96.552	0.621
comGF/cglF	Streptococcus mitis SK321	64.286	96.552	0.621
comYF	Streptococcus mutans UA159	42.963	93.103	0.4
comYF	Streptococcus mutans UA140	42.963	93.103	0.4
comGF	Lactococcus lactis subsp. cremoris KW2	40	93.103	0.372