Detailed information NTG0840764

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: F6I26_RS01175
• Genome accession: NZ_CP126961
• Coordinates: 209139..210092 (+)
• Length: 317 a.a.
• NCBI ID: WP_024053125.1
• Uniprot ID: A0A412PLM5
• Organism: Streptococcus anginosus strain UMB4708
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 204139..215092

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F6I26_RS01135 (F6I26_001135)	-	205032..205397 (+)	366	WP_024053131.1	DUF1033 family protein	-
F6I26_RS01140 (F6I26_001140)	comYA	205467..206408 (+)	942	WP_024053130.1	competence type IV pilus ATPase ComGA	Machinery gene
F6I26_RS01145 (F6I26_001145)	comYB	206350..207372 (+)	1023	WP_171021869.1	competence type IV pilus assembly protein ComGB	Machinery gene
F6I26_RS01150 (F6I26_001150)	comYC	207369..207686 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
F6I26_RS01155 (F6I26_001155)	comYD	207676..208074 (+)	399	WP_022525973.1	competence type IV pilus minor pilin ComGD	Machinery gene
F6I26_RS01160 (F6I26_001160)	comGE/cglE	208046..208339 (+)	294	WP_024053127.1	competence type IV pilus minor pilin ComGE	Machinery gene
F6I26_RS01165 (F6I26_001165)	comGF/cglF	208323..208760 (+)	438	WP_024053126.1	competence type IV pilus minor pilin ComGF	Machinery gene
F6I26_RS01170 (F6I26_001170)	comGG	208741..209067 (+)	327	WP_257360478.1	competence type IV pilus minor pilin ComGG	-
F6I26_RS01175 (F6I26_001175)	comYH	209139..210092 (+)	954	WP_024053125.1	class I SAM-dependent methyltransferase	Machinery gene
F6I26_RS01180 (F6I26_001180)	-	210139..211338 (+)	1200	WP_024053124.1	acetate kinase	-
F6I26_RS01185 (F6I26_001185)	glmS	211739..213553 (+)	1815	WP_024053123.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35821.57 Da
• Isoelectric Point: 4.2900

>NTDB_id=840764 F6I26_RS01175 WP_024053125.1 209139..210092(+) (comYH) [Streptococcus anginosus strain UMB4708]
MNFEKIEQAYTLLLENVQEIQNDLLTSFYDALIEQNGSYLDGDIELDSVRQNNEKLKALKLSKEEWRRAYQFLLMKAAQT
EPLQANHQFTPDSIGFILTFLIDQLSKKEHIDILEIGSGMGNLAETILNNTQKNVDYLGLELDDLLIDISASIADVMDAK
VSFVQGDAVRPQVLKESDVIISDLPVGFYPDDSIAARYEVASTQDHTYAHHLLMEQSLKYLKSGGYAIFLAPNDLLTSSQ
SDLLKKWLQKHAQIVAMIALPESLFGNAAYAKTIFVLKKQDEQAVQPFVYALSDLQNQADLLTFSEKFQNWSQESEI

Nucleotide

• Length: 954 bp

>NTDB_id=840764 F6I26_RS01175 WP_024053125.1 209139..210092(+) (comYH) [Streptococcus anginosus strain UMB4708]
ATGAATTTTGAAAAAATTGAACAGGCCTATACGCTCTTGTTAGAAAATGTCCAAGAAATCCAAAATGATCTTTTAACGAG
CTTTTATGATGCTTTGATAGAGCAAAATGGCAGCTATCTGGACGGGGATATTGAACTAGATAGTGTTCGGCAGAACAATG
AAAAACTGAAAGCGTTGAAATTAAGTAAAGAGGAATGGCGCCGAGCCTACCAATTTTTGCTGATGAAAGCAGCTCAAACA
GAGCCTTTGCAAGCCAATCATCAATTTACTCCAGATTCTATCGGGTTTATCTTAACTTTTCTCATTGACCAATTGAGTAA
AAAAGAACACATTGATATTTTGGAAATTGGTAGCGGAATGGGGAATTTAGCTGAGACGATTCTCAATAATACACAAAAAA
ATGTGGATTATCTAGGGCTGGAATTGGACGATCTGTTAATTGATATATCAGCCAGTATCGCAGATGTGATGGACGCAAAA
GTTAGTTTTGTGCAAGGTGACGCAGTACGCCCGCAAGTATTGAAAGAAAGCGATGTGATTATTAGCGATTTACCAGTTGG
CTTTTATCCTGATGATAGCATTGCGGCGCGCTATGAAGTGGCTAGTACACAGGATCATACCTATGCTCATCATTTGTTAA
TGGAACAATCGCTCAAGTATCTCAAATCAGGCGGTTATGCTATTTTCCTTGCACCAAATGATTTATTGACTAGTTCGCAA
AGTGATTTATTGAAGAAATGGCTACAAAAGCATGCACAAATAGTTGCAATGATTGCGTTACCAGAGTCTCTTTTTGGAAA
TGCAGCATACGCTAAAACAATTTTTGTACTGAAAAAGCAAGATGAACAAGCTGTCCAACCATTTGTTTATGCTTTATCTG
ATTTGCAGAATCAAGCGGATTTATTGACATTTAGCGAAAAGTTTCAAAATTGGAGCCAAGAAAGTGAAATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-294)

3D structure

• AlphaFold DB: A0A412PLM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	61.905	99.369	0.615
comYH	Streptococcus mutans UA159	61.587	99.369	0.612