Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   QM316_RS02470 Genome accession   NZ_CP125862
Coordinates   458656..459726 (+) Length   356 a.a.
NCBI ID   WP_000776413.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 18-02202-1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 453656..464726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QM316_RS02440 (QM316_02435) - 454079..455542 (+) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  QM316_RS02445 (QM316_02440) - 455523..455726 (+) 204 WP_000087561.1 YqgQ family protein -
  QM316_RS02450 (QM316_02445) - 455723..456709 (+) 987 WP_000161315.1 ROK family glucokinase -
  QM316_RS02455 (QM316_02450) - 456709..457038 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  QM316_RS02460 (QM316_02455) - 457035..457658 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  QM316_RS02465 (QM316_02460) comGA 457710..458684 (+) 975 WP_000697222.1 competence type IV pilus ATPase ComGA Machinery gene
  QM316_RS02470 (QM316_02465) comGB 458656..459726 (+) 1071 WP_000776413.1 competence type IV pilus assembly protein ComGB Machinery gene
  QM316_RS02475 (QM316_02470) comGC 459740..460051 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  QM316_RS02480 (QM316_02475) comGD 460029..460475 (+) 447 WP_151367112.1 competence type IV pilus minor pilin ComGD Machinery gene
  QM316_RS02485 (QM316_02480) comGE 460462..460761 (+) 300 WP_000844415.1 hypothetical protein Machinery gene
  QM316_RS02490 (QM316_02485) comGF 460679..461176 (+) 498 WP_001825340.1 competence type IV pilus minor pilin ComGF Machinery gene
  QM316_RS02495 (QM316_02490) - 461273..461419 (+) 147 WP_001789879.1 hypothetical protein -
  QM316_RS02500 (QM316_02495) - 461409..461933 (+) 525 WP_001015120.1 shikimate kinase -
  QM316_RS02505 (QM316_02500) gcvT 462092..463183 (+) 1092 WP_000093354.1 glycine cleavage system aminomethyltransferase GcvT -
  QM316_RS02510 (QM316_02505) gcvPA 463203..464549 (+) 1347 WP_000019687.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41475.94 Da        Isoelectric Point: 10.1030

>NTDB_id=833098 QM316_RS02470 WP_000776413.1 458656..459726(+) (comGB) [Staphylococcus aureus strain 18-02202-1]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILISIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNKLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=833098 QM316_RS02470 WP_000776413.1 458656..459726(+) (comGB) [Staphylococcus aureus strain 18-02202-1]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAGATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAATTTCTATTTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATCCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAGTTAATTTACAACAAATTGAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCAAATTTTAGAAAAATTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

99.438

100

0.994
  comGB Staphylococcus aureus N315

99.438

100

0.994