Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   U0N78_RS00390 Genome accession   NZ_CP140109
Coordinates   70038..71975 (+) Length   645 a.a.
NCBI ID   WP_256769046.1    Uniprot ID   -
Organism   Streptococcus suis strain 2022WUSS148     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 65038..76975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS00370 (U0N78_00370) - 65181..65804 (+) 624 WP_043025659.1 HAD-IA family hydrolase -
  U0N78_RS00375 (U0N78_00375) comR 65875..66777 (+) 903 WP_043025662.1 helix-turn-helix domain-containing protein Regulator
  U0N78_RS00380 (U0N78_00380) - 66986..68206 (+) 1221 WP_043025663.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  U0N78_RS00385 (U0N78_00385) - 68397..69920 (+) 1524 WP_043025665.1 quinol oxidase -
  U0N78_RS00390 (U0N78_00390) hexB 70038..71975 (+) 1938 WP_256769046.1 DNA mismatch repair endonuclease MutL Machinery gene
  U0N78_RS00395 (U0N78_00395) ruvA 72014..72604 (+) 591 WP_043025669.1 Holliday junction branch migration protein RuvA Machinery gene
  U0N78_RS00400 (U0N78_00400) - 73209..73778 (+) 570 WP_043025096.1 DNA-3-methyladenine glycosylase I -
  U0N78_RS00405 (U0N78_00405) cinA 73815..74996 (+) 1182 WP_043025095.1 competence/damage-inducible protein A Machinery gene
  U0N78_RS00410 (U0N78_00410) recA 75048..76199 (+) 1152 WP_004195473.1 recombinase RecA Machinery gene
  U0N78_RS00415 (U0N78_00415) spx 76359..76757 (+) 399 WP_004195475.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72808.06 Da        Isoelectric Point: 5.2313

>NTDB_id=833096 U0N78_RS00390 WP_256769046.1 70038..71975(+) (hexB) [Streptococcus suis strain 2022WUSS148]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGIIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMAALRQVGVNLEEYGANQFILREHPIWMKEEEIGSGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLIHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=833096 U0N78_RS00390 WP_256769046.1 70038..71975(+) (hexB) [Streptococcus suis strain 2022WUSS148]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTCAAAA
TGATTCAAATTACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAGTCAATCGGATTTGTTTCGTATTCGCACCCTAGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTTAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTATCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCTTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTACGTTTCCTTGCCA
GAGTTGACTCGCGCCAACCGCAACTACATTTCCATTTTCATCAATGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTATGGCAGTAAGTTGATGGTAGGACGTTTTCCATTGGCAGTGATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGTACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGATGTTGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGCGCAAAAGAATT
GGCAAAACTAGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAGATGCATGGGA
CGTATTTATTTGCGCAAGGTAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCCCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTTGTCCACAAAATGGCTGCCCTTCGTCAAGTAGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGGGTCTGGCATTTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCGATCAAGGCCAATCA
TGCTCTGGATGATTACTCGGCGCGTGATTTACTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GCCCAGTCTTAATACATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGA
GAGTTGGGGAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(447-589)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.154

100

0.727