Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   QLQ43_RS09410 Genome accession   NZ_CP124947
Coordinates   1873314..1873589 (-) Length   91 a.a.
NCBI ID   WP_002364235.1    Uniprot ID   -
Organism   Enterococcus faecalis strain EfsC43     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1833488..1891684 1873314..1873589 within 0


Gene organization within MGE regions


Location: 1833488..1891684
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QLQ43_RS09135 (QLQ43_09130) - 1833488..1834495 (-) 1008 WP_002357063.1 class I SAM-dependent methyltransferase -
  QLQ43_RS09140 (QLQ43_09135) comGG 1834624..1834977 (-) 354 WP_002360027.1 competence type IV pilus minor pilin ComGG -
  QLQ43_RS09145 (QLQ43_09140) comGF 1834977..1835411 (-) 435 WP_002357060.1 competence type IV pilus minor pilin ComGF -
  QLQ43_RS09150 (QLQ43_09145) - 1835401..1835772 (-) 372 WP_172613785.1 type II secretion system protein -
  QLQ43_RS09155 (QLQ43_09150) hemH 1836527..1837468 (-) 942 WP_302532220.1 ferrochelatase -
  QLQ43_RS09165 (QLQ43_09160) - 1838185..1838457 (-) 273 WP_002378444.1 hypothetical protein -
  QLQ43_RS09170 (QLQ43_09165) - 1838529..1838729 (-) 201 WP_002357053.1 cold-shock protein -
  QLQ43_RS09175 (QLQ43_09170) - 1839582..1840841 (-) 1260 WP_010784601.1 LysM peptidoglycan-binding domain-containing protein -
  QLQ43_RS09180 (QLQ43_09175) - 1840854..1841234 (-) 381 WP_002378446.1 phage holin family protein -
  QLQ43_RS09185 (QLQ43_09180) - 1841245..1841367 (-) 123 WP_002368228.1 XkdX family protein -
  QLQ43_RS09190 (QLQ43_09185) - 1841369..1841764 (-) 396 WP_002363385.1 hypothetical protein -
  QLQ43_RS09195 (QLQ43_09190) - 1841783..1842235 (-) 453 WP_002363384.1 hypothetical protein -
  QLQ43_RS09200 (QLQ43_09195) - 1842252..1842992 (-) 741 WP_002363383.1 hypothetical protein -
  QLQ43_RS09205 (QLQ43_09200) - 1842998..1844443 (-) 1446 WP_010784602.1 phage tail spike protein -
  QLQ43_RS09210 (QLQ43_09205) - 1844443..1845165 (-) 723 WP_010785045.1 hypothetical protein -
  QLQ43_RS09215 (QLQ43_09210) - 1845162..1849616 (-) 4455 Protein_1786 phage tail tape measure protein -
  QLQ43_RS09220 (QLQ43_09215) - 1849603..1849908 (-) 306 WP_002364305.1 hypothetical protein -
  QLQ43_RS09225 (QLQ43_09220) - 1849977..1850375 (-) 399 WP_002409775.1 tail assembly chaperone -
  QLQ43_RS09230 (QLQ43_09225) - 1850438..1850746 (-) 309 WP_010785047.1 hypothetical protein -
  QLQ43_RS09235 (QLQ43_09230) - 1850749..1851354 (-) 606 WP_002364302.1 phage major tail protein, TP901-1 family -
  QLQ43_RS09240 (QLQ43_09235) - 1851373..1851765 (-) 393 WP_002363373.1 DUF3168 domain-containing protein -
  QLQ43_RS09245 (QLQ43_09240) - 1851762..1852100 (-) 339 WP_002363372.1 HK97-gp10 family putative phage morphogenesis protein -
  QLQ43_RS09250 (QLQ43_09245) - 1852097..1852372 (-) 276 WP_002364301.1 hypothetical protein -
  QLQ43_RS09255 (QLQ43_09250) - 1852369..1852701 (-) 333 WP_002363369.1 phage head-tail connector protein -
  QLQ43_RS09260 (QLQ43_09255) - 1852772..1853668 (-) 897 WP_002363368.1 hypothetical protein -
  QLQ43_RS09265 (QLQ43_09260) - 1853681..1854316 (-) 636 WP_254615300.1 DUF4355 domain-containing protein -
  QLQ43_RS09270 (QLQ43_09265) - 1854439..1855365 (-) 927 WP_002363365.1 minor capsid protein -
  QLQ43_RS09275 (QLQ43_09270) - 1855358..1856842 (-) 1485 WP_010784607.1 phage portal protein -
  QLQ43_RS09280 (QLQ43_09275) - 1856842..1858125 (-) 1284 WP_002369892.1 PBSX family phage terminase large subunit -
  QLQ43_RS09285 (QLQ43_09280) - 1858106..1858540 (-) 435 WP_002364295.1 terminase small subunit -
  QLQ43_RS09290 (QLQ43_09285) - 1858572..1858802 (-) 231 WP_010784608.1 hypothetical protein -
  QLQ43_RS09295 (QLQ43_09290) - 1859235..1859702 (-) 468 WP_010784780.1 hypothetical protein -
  QLQ43_RS09300 (QLQ43_09295) - 1859728..1860678 (-) 951 WP_010784610.1 hypothetical protein -
  QLQ43_RS09310 (QLQ43_09305) - 1861388..1861804 (-) 417 WP_002357018.1 ArpU family phage packaging/lysis transcriptional regulator -
  QLQ43_RS09315 (QLQ43_09310) - 1862711..1863118 (-) 408 WP_024797260.1 RusA family crossover junction endodeoxyribonuclease -
  QLQ43_RS09320 (QLQ43_09315) - 1863115..1863972 (-) 858 WP_002364343.1 helix-turn-helix domain-containing protein -
  QLQ43_RS09325 (QLQ43_09320) - 1863972..1864172 (-) 201 WP_002357010.1 hypothetical protein -
  QLQ43_RS09330 (QLQ43_09325) - 1864177..1864818 (-) 642 WP_002364344.1 putative HNHc nuclease -
  QLQ43_RS09335 (QLQ43_09330) - 1864823..1865557 (-) 735 WP_002364345.1 ERF family protein -
  QLQ43_RS09340 (QLQ43_09335) - 1865550..1865867 (-) 318 WP_002357007.1 hypothetical protein -
  QLQ43_RS09345 (QLQ43_09340) - 1866087..1866641 (+) 555 WP_002357006.1 hypothetical protein -
  QLQ43_RS09350 (QLQ43_09345) - 1866926..1867264 (-) 339 WP_033783419.1 hypothetical protein -
  QLQ43_RS09355 (QLQ43_09350) - 1867301..1867510 (-) 210 WP_002399426.1 hypothetical protein -
  QLQ43_RS09360 (QLQ43_09355) - 1867565..1867753 (+) 189 WP_002364350.1 YegP family protein -
  QLQ43_RS09365 (QLQ43_09360) - 1867779..1868504 (-) 726 WP_002364352.1 phage regulatory protein -
  QLQ43_RS09370 (QLQ43_09365) - 1868543..1868854 (-) 312 WP_002381719.1 hypothetical protein -
  QLQ43_RS14750 - 1868866..1869033 (-) 168 WP_033624736.1 hypothetical protein -
  QLQ43_RS09375 (QLQ43_09370) - 1869451..1869648 (-) 198 WP_010712611.1 hypothetical protein -
  QLQ43_RS09380 (QLQ43_09375) - 1869661..1869843 (-) 183 WP_002358110.1 hypothetical protein -
  QLQ43_RS09385 (QLQ43_09380) - 1870141..1870473 (+) 333 WP_002392358.1 helix-turn-helix domain-containing protein -
  QLQ43_RS09390 (QLQ43_09385) - 1870491..1870835 (+) 345 WP_002378467.1 ImmA/IrrE family metallo-endopeptidase -
  QLQ43_RS09395 (QLQ43_09390) - 1870870..1871598 (+) 729 WP_010784612.1 ion transporter -
  QLQ43_RS09400 (QLQ43_09395) - 1871698..1872846 (+) 1149 WP_002388210.1 site-specific integrase -
  QLQ43_RS09405 (QLQ43_09400) comGD 1872874..1873317 (-) 444 WP_002388212.1 competence type IV pilus minor pilin ComGD -
  QLQ43_RS09410 (QLQ43_09405) comGC/cglC 1873314..1873589 (-) 276 WP_002364235.1 competence type IV pilus major pilin ComGC Machinery gene
  QLQ43_RS09415 (QLQ43_09410) comGB 1873589..1874635 (-) 1047 WP_002403888.1 competence type IV pilus assembly protein ComGB -
  QLQ43_RS09420 (QLQ43_09415) comGA 1874592..1875560 (-) 969 WP_002364237.1 competence type IV pilus ATPase ComGA -
  QLQ43_RS09425 (QLQ43_09420) - 1875801..1877129 (-) 1329 WP_010784613.1 APC family permease -
  QLQ43_RS09430 (QLQ43_09425) rlmN 1877419..1878492 (-) 1074 WP_002364241.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  QLQ43_RS09435 (QLQ43_09430) - 1878616..1880445 (-) 1830 WP_002403891.1 ABC transporter permease -
  QLQ43_RS09440 (QLQ43_09435) - 1880435..1881184 (-) 750 WP_002384339.1 ABC transporter ATP-binding protein -
  QLQ43_RS09445 (QLQ43_09440) - 1881302..1882003 (-) 702 WP_002364244.1 GntR family transcriptional regulator -
  QLQ43_RS09450 (QLQ43_09445) - 1882124..1884547 (-) 2424 WP_002362065.1 DNA translocase FtsK -
  QLQ43_RS09455 (QLQ43_09450) - 1884861..1886072 (-) 1212 WP_002364245.1 NAD(P)/FAD-dependent oxidoreductase -
  QLQ43_RS09460 (QLQ43_09455) - 1886101..1887006 (-) 906 WP_002360016.1 prenyltransferase -
  QLQ43_RS09465 (QLQ43_09460) - 1887128..1888108 (+) 981 WP_002360015.1 polyprenyl synthetase family protein -
  QLQ43_RS09470 (QLQ43_09465) cydC 1888188..1889954 (-) 1767 WP_002364246.1 thiol reductant ABC exporter subunit CydC -
  QLQ43_RS09475 (QLQ43_09470) cydD 1889951..1891684 (-) 1734 WP_002364247.1 thiol reductant ABC exporter subunit CydD -

Sequence

Protein


Download         Length: 91 a.a.        Molecular weight: 10506.50 Da        Isoelectric Point: 9.6586

>NTDB_id=829654 QLQ43_RS09410 WP_002364235.1 1873314..1873589(-) (comGC/cglC) [Enterococcus faecalis strain EfsC43]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNRTPSLNELVKEGYITK
EQLDKYTAEKQ

Nucleotide


Download         Length: 276 bp        

>NTDB_id=829654 QLQ43_RS09410 WP_002364235.1 1873314..1873589(-) (comGC/cglC) [Enterococcus faecalis strain EfsC43]
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATCATTTCCGTATTGATTTT
ACTTTTTGTTCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAGGACGCCTTCTTTAAATGAATTAGTCAAAGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae D39

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae R6

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae TIGR4

63.095

92.308

0.582
  comGC/cglC Streptococcus mitis NCTC 12261

61.905

92.308

0.571
  comGC/cglC Streptococcus mitis SK321

61.176

93.407

0.571
  comGC Lactococcus lactis subsp. cremoris KW2

58.14

94.505

0.549
  comYC Streptococcus gordonii str. Challis substr. CH1

56.322

95.604

0.538
  comYC Streptococcus suis isolate S10

52.326

94.505

0.495
  comYC Streptococcus mutans UA159

57.692

85.714

0.495
  comYC Streptococcus mutans UA140

57.692

85.714

0.495
  comGC Latilactobacillus sakei subsp. sakei 23K

46.154

100

0.462
  comGC Staphylococcus aureus MW2

48.101

86.813

0.418
  comGC Staphylococcus aureus N315

48.101

86.813

0.418
  comGC Bacillus subtilis subsp. subtilis str. 168

48.649

81.319

0.396