Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   QLQ57_RS09335 Genome accession   NZ_CP124925
Coordinates   1876711..1876986 (-) Length   91 a.a.
NCBI ID   WP_002364235.1    Uniprot ID   -
Organism   Enterococcus faecalis strain EfsPF36     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1832474..1895091 1876711..1876986 within 0


Gene organization within MGE regions


Location: 1832474..1895091
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QLQ57_RS09035 (QLQ57_09035) - 1832474..1833481 (-) 1008 WP_002357063.1 class I SAM-dependent methyltransferase -
  QLQ57_RS09040 (QLQ57_09040) comGG 1833610..1833963 (-) 354 WP_002360027.1 competence type IV pilus minor pilin ComGG -
  QLQ57_RS09045 (QLQ57_09045) comGF 1833963..1834397 (-) 435 WP_002357060.1 competence type IV pilus minor pilin ComGF -
  QLQ57_RS09050 (QLQ57_09050) - 1834387..1834713 (-) 327 WP_002370967.1 type II secretion system protein -
  QLQ57_RS09055 (QLQ57_09055) hemH 1835515..1836456 (-) 942 WP_002357056.1 ferrochelatase -
  QLQ57_RS09065 (QLQ57_09065) - 1837172..1837444 (-) 273 WP_002370964.1 hypothetical protein -
  QLQ57_RS09070 (QLQ57_09070) - 1837516..1837716 (-) 201 WP_002357053.1 cold-shock protein -
  QLQ57_RS09075 (QLQ57_09075) - 1838575..1839816 (-) 1242 WP_002384372.1 LysM peptidoglycan-binding domain-containing protein -
  QLQ57_RS09080 (QLQ57_09080) - 1839817..1840050 (-) 234 WP_002384371.1 phage holin -
  QLQ57_RS09085 (QLQ57_09085) - 1840043..1840264 (-) 222 WP_002364191.1 hypothetical protein -
  QLQ57_RS09090 (QLQ57_09090) - 1840299..1840454 (-) 156 WP_002364192.1 XkdX family protein -
  QLQ57_RS09095 (QLQ57_09095) - 1840456..1840776 (-) 321 WP_010774127.1 hypothetical protein -
  QLQ57_RS09100 (QLQ57_09100) - 1840790..1841281 (-) 492 WP_002364194.1 hypothetical protein -
  QLQ57_RS09105 (QLQ57_09105) - 1841281..1841568 (-) 288 WP_002357046.1 collagen-like protein -
  QLQ57_RS09110 (QLQ57_09110) - 1841565..1842161 (-) 597 WP_002357045.1 hypothetical protein -
  QLQ57_RS09115 (QLQ57_09115) - 1842154..1843035 (-) 882 WP_002357044.1 phage baseplate upper protein -
  QLQ57_RS09120 (QLQ57_09120) - 1843054..1845861 (-) 2808 WP_002384367.1 phage tail spike protein -
  QLQ57_RS09125 (QLQ57_09125) - 1845843..1846577 (-) 735 WP_002357042.1 hypothetical protein -
  QLQ57_RS09130 (QLQ57_09130) - 1846567..1849464 (-) 2898 Protein_1775 tape measure protein -
  QLQ57_RS09135 (QLQ57_09135) - 1849712..1850062 (-) 351 WP_002357039.1 hypothetical protein -
  QLQ57_RS09140 (QLQ57_09140) - 1850115..1850963 (-) 849 WP_002384363.1 major tail protein -
  QLQ57_RS09145 (QLQ57_09145) - 1850964..1851338 (-) 375 WP_002357037.1 DUF6838 family protein -
  QLQ57_RS09150 (QLQ57_09150) - 1851341..1851685 (-) 345 WP_002392208.1 HK97 gp10 family phage protein -
  QLQ57_RS09155 (QLQ57_09155) - 1852039..1853289 (+) 1251 WP_002346915.1 IS110 family transposase -
  QLQ57_RS15465 - 1853427..1853510 (-) 84 Protein_1781 HK97 gp10 family phage protein -
  QLQ57_RS09160 (QLQ57_09160) - 1853503..1853871 (-) 369 WP_142428003.1 hypothetical protein -
  QLQ57_RS09165 (QLQ57_09165) - 1853868..1854212 (-) 345 WP_002387282.1 hypothetical protein -
  QLQ57_RS09170 (QLQ57_09170) - 1854226..1854408 (-) 183 WP_002357032.1 hypothetical protein -
  QLQ57_RS09175 (QLQ57_09175) - 1854437..1855324 (-) 888 WP_002357030.1 DUF5309 domain-containing protein -
  QLQ57_RS09180 (QLQ57_09180) - 1855338..1855961 (-) 624 WP_002389133.1 DUF4355 domain-containing protein -
  QLQ57_RS09185 (QLQ57_09185) - 1856179..1856499 (-) 321 WP_002389265.1 hypothetical protein -
  QLQ57_RS09190 (QLQ57_09190) - 1856564..1856785 (-) 222 WP_002357027.1 hypothetical protein -
  QLQ57_RS09195 (QLQ57_09195) - 1856782..1858539 (-) 1758 WP_002384360.1 head protein -
  QLQ57_RS09200 (QLQ57_09200) - 1858514..1860001 (-) 1488 WP_002384358.1 phage portal protein -
  QLQ57_RS09205 (QLQ57_09205) - 1860013..1861302 (-) 1290 WP_002357024.1 PBSX family phage terminase large subunit -
  QLQ57_RS09210 (QLQ57_09210) terS 1861274..1862077 (-) 804 WP_002364203.1 phage terminase small subunit -
  QLQ57_RS09215 (QLQ57_09215) - 1862124..1862846 (-) 723 WP_010815494.1 DUF5677 domain-containing protein -
  QLQ57_RS09220 (QLQ57_09220) - 1863563..1864177 (-) 615 WP_002384355.1 hypothetical protein -
  QLQ57_RS09230 (QLQ57_09230) - 1864708..1865124 (-) 417 WP_002364209.1 ArpU family phage packaging/lysis transcriptional regulator -
  QLQ57_RS09235 (QLQ57_09235) - 1866031..1866454 (-) 424 Protein_1796 RusA family crossover junction endodeoxyribonuclease -
  QLQ57_RS09240 (QLQ57_09240) - 1866472..1866771 (-) 300 WP_002357015.1 MazG-like family protein -
  QLQ57_RS09245 (QLQ57_09245) - 1866772..1867074 (-) 303 WP_002364215.1 hypothetical protein -
  QLQ57_RS09250 (QLQ57_09250) - 1867078..1868040 (-) 963 WP_002364216.1 Lin1244/Lin1753 domain-containing protein -
  QLQ57_RS09255 (QLQ57_09255) - 1868054..1868944 (-) 891 WP_010708318.1 recombinase RecT -
  QLQ57_RS09260 (QLQ57_09260) - 1868947..1869888 (-) 942 WP_002384348.1 YqaJ viral recombinase family protein -
  QLQ57_RS09265 (QLQ57_09265) - 1869986..1870213 (-) 228 WP_002364220.1 hypothetical protein -
  QLQ57_RS09270 (QLQ57_09270) - 1870213..1870536 (-) 324 WP_002369793.1 hypothetical protein -
  QLQ57_RS09275 (QLQ57_09275) - 1870580..1870772 (-) 193 Protein_1804 hypothetical protein -
  QLQ57_RS09280 (QLQ57_09280) - 1870763..1870957 (-) 195 WP_002364223.1 hypothetical protein -
  QLQ57_RS09285 (QLQ57_09285) - 1871010..1871192 (+) 183 WP_002364224.1 YegP family protein -
  QLQ57_RS09290 (QLQ57_09290) - 1871232..1871954 (-) 723 WP_002364225.1 phage regulatory protein -
  QLQ57_RS09295 (QLQ57_09295) - 1871993..1872310 (-) 318 WP_002364228.1 hypothetical protein -
  QLQ57_RS09300 (QLQ57_09300) - 1872316..1872507 (-) 192 WP_002356998.1 hypothetical protein -
  QLQ57_RS09305 (QLQ57_09305) - 1872798..1873142 (+) 345 WP_002384346.1 helix-turn-helix domain-containing protein -
  QLQ57_RS09310 (QLQ57_09310) - 1873147..1873794 (+) 648 WP_002372050.1 ImmA/IrrE family metallo-endopeptidase -
  QLQ57_RS09315 (QLQ57_09315) - 1873912..1874676 (+) 765 WP_002389030.1 LysM domain-containing protein -
  QLQ57_RS09320 (QLQ57_09320) - 1874691..1875020 (+) 330 WP_002369911.1 hypothetical protein -
  QLQ57_RS09325 (QLQ57_09325) - 1875095..1876243 (+) 1149 WP_002389015.1 site-specific integrase -
  QLQ57_RS09330 (QLQ57_09330) comGD 1876271..1876714 (-) 444 WP_002384345.1 competence type IV pilus minor pilin ComGD -
  QLQ57_RS09335 (QLQ57_09335) comGC/cglC 1876711..1876986 (-) 276 WP_002364235.1 competence type IV pilus major pilin ComGC Machinery gene
  QLQ57_RS09340 (QLQ57_09340) comGB 1876986..1878032 (-) 1047 WP_002384344.1 competence type IV pilus assembly protein ComGB -
  QLQ57_RS09345 (QLQ57_09345) comGA 1877989..1878957 (-) 969 WP_002364237.1 competence type IV pilus ATPase ComGA -
  QLQ57_RS09350 (QLQ57_09350) - 1879198..1880526 (-) 1329 WP_002384343.1 APC family permease -
  QLQ57_RS09355 (QLQ57_09355) rlmN 1880816..1881889 (-) 1074 WP_002384342.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  QLQ57_RS09360 (QLQ57_09360) - 1882013..1883842 (-) 1830 WP_002384340.1 ABC transporter permease -
  QLQ57_RS09365 (QLQ57_09365) - 1883832..1884581 (-) 750 WP_002384339.1 ABC transporter ATP-binding protein -
  QLQ57_RS09370 (QLQ57_09370) - 1884699..1885400 (-) 702 WP_002364244.1 GntR family transcriptional regulator -
  QLQ57_RS09375 (QLQ57_09375) - 1885531..1887954 (-) 2424 WP_002384338.1 DNA translocase FtsK -
  QLQ57_RS09380 (QLQ57_09380) - 1888268..1889479 (-) 1212 WP_002360017.1 NAD(P)/FAD-dependent oxidoreductase -
  QLQ57_RS09385 (QLQ57_09385) - 1889508..1890413 (-) 906 WP_002384337.1 prenyltransferase -
  QLQ57_RS09390 (QLQ57_09390) - 1890535..1891515 (+) 981 WP_002360015.1 polyprenyl synthetase family protein -
  QLQ57_RS09395 (QLQ57_09395) cydC 1891595..1893361 (-) 1767 WP_002364246.1 thiol reductant ABC exporter subunit CydC -
  QLQ57_RS09400 (QLQ57_09400) cydD 1893358..1895091 (-) 1734 WP_002384336.1 thiol reductant ABC exporter subunit CydD -

Sequence

Protein


Download         Length: 91 a.a.        Molecular weight: 10506.50 Da        Isoelectric Point: 9.6586

>NTDB_id=829466 QLQ57_RS09335 WP_002364235.1 1876711..1876986(-) (comGC/cglC) [Enterococcus faecalis strain EfsPF36]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNRTPSLNELVKEGYITK
EQLDKYTAEKQ

Nucleotide


Download         Length: 276 bp        

>NTDB_id=829466 QLQ57_RS09335 WP_002364235.1 1876711..1876986(-) (comGC/cglC) [Enterococcus faecalis strain EfsPF36]
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATCATTTCCGTATTGATTTT
ACTTTTTGTTCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAGGACGCCTTCTTTAAATGAATTAGTCAAAGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae D39

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae R6

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae TIGR4

63.095

92.308

0.582
  comGC/cglC Streptococcus mitis NCTC 12261

61.905

92.308

0.571
  comGC/cglC Streptococcus mitis SK321

61.176

93.407

0.571
  comGC Lactococcus lactis subsp. cremoris KW2

58.14

94.505

0.549
  comYC Streptococcus gordonii str. Challis substr. CH1

56.322

95.604

0.538
  comYC Streptococcus suis isolate S10

52.326

94.505

0.495
  comYC Streptococcus mutans UA159

57.692

85.714

0.495
  comYC Streptococcus mutans UA140

57.692

85.714

0.495
  comGC Latilactobacillus sakei subsp. sakei 23K

46.154

100

0.462
  comGC Staphylococcus aureus MW2

48.101

86.813

0.418
  comGC Staphylococcus aureus N315

48.101

86.813

0.418
  comGC Bacillus subtilis subsp. subtilis str. 168

48.649

81.319

0.396