Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   QJV49_RS06435 Genome accession   NZ_CP124538
Coordinates   1272720..1273658 (-) Length   312 a.a.
NCBI ID   WP_225512501.1    Uniprot ID   A0AA49EYV2
Organism   Lactococcus sp. NH2-7C     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1267720..1278658
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QJV49_RS06395 (QJV49_06395) - 1268607..1269449 (-) 843 WP_225512507.1 metal ABC transporter substrate-binding protein -
  QJV49_RS06400 (QJV49_06400) - 1269446..1269883 (-) 438 WP_010906313.1 zinc-dependent MarR family transcriptional regulator -
  QJV49_RS06405 (QJV49_06405) comGG 1269965..1270240 (-) 276 WP_225512506.1 competence protein ComGG Machinery gene
  QJV49_RS06410 (QJV49_06410) comGF 1270288..1270734 (-) 447 WP_370632039.1 competence type IV pilus minor pilin ComGF Machinery gene
  QJV49_RS06415 (QJV49_06415) comGE 1270697..1270993 (-) 297 WP_225512504.1 competence type IV pilus minor pilin ComGE Machinery gene
  QJV49_RS06420 (QJV49_06420) comGD 1270965..1271396 (-) 432 WP_225512503.1 competence type IV pilus minor pilin ComGD Machinery gene
  QJV49_RS06425 (QJV49_06425) comGC 1271356..1271625 (-) 270 WP_281449176.1 competence type IV pilus major pilin ComGC Machinery gene
  QJV49_RS06430 (QJV49_06430) comGB 1271753..1272826 (-) 1074 WP_225512580.1 competence type IV pilus assembly protein ComGB Machinery gene
  QJV49_RS06435 (QJV49_06435) comGA 1272720..1273658 (-) 939 WP_225512501.1 competence type IV pilus ATPase ComGA Machinery gene

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35644.91 Da        Isoelectric Point: 6.4009

>NTDB_id=826336 QJV49_RS06435 WP_225512501.1 1272720..1273658(-) (comGA) [Lactococcus sp. NH2-7C]
MIPKMAKELIQKAIDRGASDIYLIASKEKYKLYFRQMTARVLVEEIELEVGLALLTHFKFLAGMNTGERRRVQLGACWYE
LEESNAKRLRLSTVGDFEGNESLVIRLLHDQNKELDFWFDEELDNYDCKRGLHLFAGPVGSGKTSLMFDLARRHFTGLQV
ITIEEPVELIDSDFIQLQVNEVIGNSYDELIKLSLRHRPDLLIVGEIRDKLTAQAVLRASLTGYTVFSTVHAASVRGVIQ
RLSELGLSHWEIKNALSSVVYQRLIAGKGILDIAKNEFESWSSENWNKKIDQLLTNGYLTPNEAKREKIRTD

Nucleotide


Download         Length: 939 bp        

>NTDB_id=826336 QJV49_RS06435 WP_225512501.1 1272720..1273658(-) (comGA) [Lactococcus sp. NH2-7C]
ATGATACCAAAAATGGCAAAAGAATTAATTCAAAAAGCAATTGATAGAGGTGCATCAGATATTTATCTGATTGCTTCAAA
AGAAAAGTATAAACTTTATTTTCGACAAATGACAGCGCGTGTTCTGGTGGAAGAAATTGAGTTAGAAGTTGGTTTAGCAT
TACTTACTCACTTTAAGTTTCTAGCTGGGATGAATACGGGTGAACGCAGACGAGTTCAATTGGGAGCTTGTTGGTATGAA
TTAGAGGAAAGTAATGCAAAACGTTTGCGTCTTTCAACGGTGGGGGATTTCGAGGGTAATGAATCTTTAGTGATACGTCT
CTTGCATGATCAAAACAAAGAACTTGATTTTTGGTTTGATGAAGAACTAGATAATTATGATTGTAAAAGAGGATTGCATC
TTTTTGCTGGTCCAGTAGGCTCGGGCAAAACATCTTTAATGTTTGATTTAGCGCGTCGTCATTTTACAGGTTTACAAGTT
ATCACTATTGAAGAACCCGTTGAGTTGATTGATTCTGATTTTATTCAATTACAAGTCAACGAAGTGATTGGTAACAGTTA
TGATGAATTAATTAAATTATCACTGAGGCATCGTCCAGATTTGTTAATCGTTGGTGAAATTCGTGATAAATTGACCGCTC
AAGCAGTTTTACGGGCTAGTTTGACAGGCTATACAGTGTTTTCAACTGTTCATGCCGCTTCTGTTAGAGGTGTCATTCAG
AGATTATCAGAGCTGGGTTTAAGTCATTGGGAAATAAAAAATGCTTTATCAAGTGTTGTTTATCAGCGTTTAATAGCTGG
GAAAGGAATATTAGACATTGCCAAAAACGAATTTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTAC
TTACAAATGGATATCTCACACCTAATGAAGCCAAGAGGGAAAAAATTAGGACTGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Lactococcus lactis subsp. cremoris KW2

78.317

99.038

0.776
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

54.341

99.679

0.542
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

54.341

99.679

0.542
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

53.376

99.679

0.532
  comGA/cglA/cilD Streptococcus pneumoniae R6

53.376

99.679

0.532
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

53.376

99.679

0.532
  comGA/cglA/cilD Streptococcus pneumoniae D39

53.376

99.679

0.532
  comYA Streptococcus mutans UA140

52.733

99.679

0.526
  comYA Streptococcus mutans UA159

52.733

99.679

0.526
  comYA Streptococcus gordonii str. Challis substr. CH1

52.244

100

0.522