Detailed information NTG0826335

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: QJV49_RS06430
• Genome accession: NZ_CP124538
• Coordinates: 1271753..1272826 (-)
• Length: 357 a.a.
• NCBI ID: WP_225512580.1
• Uniprot ID: -
• Organism: Lactococcus sp. NH2-7C
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1266753..1277826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QJV49_RS06385 (QJV49_06385)	-	1266891..1267700 (-)	810	WP_014570791.1	metal ABC transporter permease	-
QJV49_RS06390 (QJV49_06390)	-	1267693..1268430 (-)	738	WP_012898617.1	metal ABC transporter ATP-binding protein	-
QJV49_RS06395 (QJV49_06395)	-	1268607..1269449 (-)	843	WP_225512507.1	metal ABC transporter substrate-binding protein	-
QJV49_RS06400 (QJV49_06400)	-	1269446..1269883 (-)	438	WP_010906313.1	zinc-dependent MarR family transcriptional regulator	-
QJV49_RS06405 (QJV49_06405)	comGG	1269965..1270240 (-)	276	WP_225512506.1	competence protein ComGG	Machinery gene
QJV49_RS06410 (QJV49_06410)	comGF	1270288..1270734 (-)	447	WP_370632039.1	competence type IV pilus minor pilin ComGF	Machinery gene
QJV49_RS06415 (QJV49_06415)	comGE	1270697..1270993 (-)	297	WP_225512504.1	competence type IV pilus minor pilin ComGE	Machinery gene
QJV49_RS06420 (QJV49_06420)	comGD	1270965..1271396 (-)	432	WP_225512503.1	competence type IV pilus minor pilin ComGD	Machinery gene
QJV49_RS06425 (QJV49_06425)	comGC	1271356..1271625 (-)	270	WP_281449176.1	competence type IV pilus major pilin ComGC	Machinery gene
QJV49_RS06430 (QJV49_06430)	comGB	1271753..1272826 (-)	1074	WP_225512580.1	competence type IV pilus assembly protein ComGB	Machinery gene
QJV49_RS06435 (QJV49_06435)	comGA	1272720..1273658 (-)	939	WP_225512501.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 40439.56 Da
• Isoelectric Point: 10.1848

>NTDB_id=826335 QJV49_RS06430 WP_225512580.1 1271753..1272826(-) (comGB) [Lactococcus sp. NH2-7C]
MSLGHQKIGIKKLISYLQMDISHLMKPRGKKLGLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLA
SGQSLSELLESLLFSKNVVTQLALVEVHGNLSGTMQLVELHLKKQLKVKKKLVEVATYPVLLLIFLVGIMWGLKNYLLPQ
LNSGSNFTTLLINHLPLVFFSFGAFMFLLTALSVTLFKRKSAITNFTFLAKLPLIHPFIRLYLTAYFSREWGNLITQGVE
LRQIINLMKKQKSRIFSEVGEKLDLDLNAGRSFEQAVSNLKLFLPELSLMIEYGAIKDKLGLELSLYADECWEQFFTKID
WLMQLIQPLIFVFVALMIVLLYAAMLLPIYSNMGSGI

Nucleotide

• Length: 1074 bp

>NTDB_id=826335 QJV49_RS06430 WP_225512580.1 1271753..1272826(-) (comGB) [Lactococcus sp. NH2-7C]
TTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTACTTACAAATGGATATCTCACACCTAATGAAGCC
AAGAGGGAAAAAATTAGGACTGATTAAACAAGCCAAACTTATCCAACTGATGGGAAATCTCTTGAATAGTGGATTTAATT
TAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTACCTTGAAAATGAAAGAAGGTCTCGCT
TCTGGTCAATCTTTATCAGAGCTTTTAGAAAGTCTTTTATTTTCTAAAAATGTAGTGACACAACTTGCTTTGGTAGAAGT
GCATGGTAACTTGTCAGGAACAATGCAGTTGGTTGAACTTCATTTAAAAAAGCAACTTAAAGTTAAAAAGAAATTAGTGG
AAGTTGCCACTTATCCAGTATTGTTATTAATTTTTTTGGTTGGAATTATGTGGGGCTTAAAAAACTATTTATTACCACAA
CTTAATAGTGGTAGTAACTTTACTACGCTGTTAATTAATCATTTACCCTTGGTATTTTTTTCATTTGGAGCTTTTATGTT
TTTACTGACAGCTTTGTCAGTAACTCTTTTCAAGCGTAAATCAGCAATAACGAATTTTACATTTCTTGCTAAATTACCAC
TGATTCATCCTTTTATTCGTTTATACTTAACCGCTTACTTCTCAAGAGAATGGGGAAATCTAATTACTCAAGGTGTCGAG
TTACGACAAATTATCAACTTGATGAAAAAACAAAAAAGTAGAATTTTTTCAGAAGTTGGTGAGAAACTTGATTTAGACTT
GAATGCTGGTCGGTCTTTTGAACAAGCTGTCAGTAATCTTAAGCTTTTTTTACCAGAGCTTTCTTTAATGATTGAATATG
GAGCTATCAAGGATAAATTAGGTTTGGAGCTTTCGTTGTATGCAGATGAATGTTGGGAACAATTTTTTACAAAGATAGAT
TGGTTAATGCAATTAATTCAACCTCTCATTTTTGTGTTCGTGGCTTTAATGATCGTTTTATTATATGCAGCCATGCTATT
GCCTATCTACTCTAATATGGGTTCCGGAATATAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (227-348)

• Type II secretion system (T2SS), protein F (T2SSF) (41-159)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Lactococcus lactis subsp. cremoris KW2	82.698	95.518	0.79
comYB	Streptococcus mutans UA159	53.372	95.518	0.51
comYB	Streptococcus mutans UA140	53.372	95.518	0.51
comYB	Streptococcus gordonii str. Challis substr. CH1	53.079	95.518	0.507
comGB/cglB	Streptococcus pneumoniae Rx1	51.343	93.838	0.482
comGB/cglB	Streptococcus pneumoniae R6	51.343	93.838	0.482
comGB/cglB	Streptococcus pneumoniae TIGR4	51.343	93.838	0.482
comGB/cglB	Streptococcus pneumoniae D39	51.343	93.838	0.482
comGB/cglB	Streptococcus mitis SK321	50.746	93.838	0.476
comGB/cglB	Streptococcus mitis NCTC 12261	49.851	93.838	0.468