Detailed information NTG0819166

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QAO41_RS09525
• Genome accession: NZ_CP123126
• Coordinates: 1934120..1935163 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain GE-MSSA32
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1929120..1940163

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO41_RS09495 (QAO41_09490)	-	1929542..1930798 (-)	1257	WP_072419726.1	aminopeptidase	-
QAO41_RS09500 (QAO41_09495)	-	1930801..1931001 (-)	201	WP_000180460.1	DUF1128 family protein	-
QAO41_RS09505 (QAO41_09500)	-	1931148..1931612 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QAO41_RS09510 (QAO41_09505)	-	1931619..1931894 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QAO41_RS09515 (QAO41_09510)	-	1932172..1933389 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QAO41_RS09520 (QAO41_09515)	vraR	1933501..1934130 (-)	630	WP_000153536.1	two-component system response regulator VraR	Regulator
QAO41_RS09525 (QAO41_09520)	vraS	1934120..1935163 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QAO41_RS09530 (QAO41_09525)	liaF	1935160..1935861 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QAO41_RS09535 (QAO41_09530)	-	1935876..1936262 (-)	387	WP_001110179.1	hypothetical protein	-
QAO41_RS09540 (QAO41_09535)	map	1936479..1937237 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QAO41_RS09545 (QAO41_09540)	-	1937768..1938754 (+)	987	WP_016187815.1	FUSC family protein	-
QAO41_RS09550 (QAO41_09545)	-	1939244..1939657 (-)	414	WP_001566709.1	hypothetical protein	-
QAO41_RS09555 (QAO41_09550)	-	1939686..1939796 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=819166 QAO41_RS09525 WP_001017131.1 1934120..1935163(-) (vraS) [Staphylococcus aureus strain GE-MSSA32]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=819166 QAO41_RS09525 WP_001017131.1 1934120..1935163(-) (vraS) [Staphylococcus aureus strain GE-MSSA32]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGCATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1