Detailed information NTG0819171

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAO41_RS13055
• Genome accession: NZ_CP123126
• Coordinates: 2627131..2628018 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain GE-MSSA32
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2622131..2633018

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO41_RS13025 (QAO41_13020)	-	2622150..2622242 (+)	93	WP_010956583.1	hypothetical protein	-
QAO41_RS13030 (QAO41_13025)	-	2622350..2622847 (-)	498	WP_001065268.1	glutathione peroxidase	-
QAO41_RS13035 (QAO41_13030)	-	2622857..2623117 (-)	261	WP_001791974.1	hypothetical protein	-
QAO41_RS13040 (QAO41_13035)	-	2623499..2623612 (-)	114	Protein_2526	hypothetical protein	-
QAO41_RS13045 (QAO41_13040)	-	2624271..2626271 (-)	2001	WP_000776740.1	ABC transporter permease	-
QAO41_RS13050 (QAO41_13045)	-	2626268..2627023 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QAO41_RS13055 (QAO41_13050)	braS	2627131..2628018 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAO41_RS13060 (QAO41_13055)	nsaR	2628029..2628693 (-)	665	Protein_2530	nisin susceptibility-associated two-component system response regulator NsaR	-
QAO41_RS13065 (QAO41_13060)	-	2628719..2628919 (-)	201	WP_000604727.1	hypothetical protein	-
QAO41_RS13070 (QAO41_13065)	-	2629117..2630541 (+)	1425	WP_000953748.1	alkaline phosphatase	-
QAO41_RS13075	-	2630601..2630702 (-)	102	WP_000731972.1	SE2200 family small protein	-
QAO41_RS13080 (QAO41_13075)	-	2630824..2631279 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAO41_RS13085 (QAO41_13080)	-	2631524..2632285 (-)	762	WP_117440043.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=819171 QAO41_RS13055 WP_000143417.1 2627131..2628018(-) (braS) [Staphylococcus aureus strain GE-MSSA32]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=819171 QAO41_RS13055 WP_000143417.1 2627131..2628018(-) (braS) [Staphylococcus aureus strain GE-MSSA32]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99