Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   LLUC147_RS11175 Genome accession   NZ_CP120473
Coordinates   2187240..2188220 (-) Length   326 a.a.
NCBI ID   WP_162494683.1    Uniprot ID   -
Organism   Lactococcus cremoris strain UC147     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2182240..2193220
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC147_RS11130 (LLUC147_11165) - 2182258..2182995 (-) 738 WP_011677178.1 metal ABC transporter ATP-binding protein -
  LLUC147_RS11135 (LLUC147_11170) - 2183174..2184016 (-) 843 WP_011677179.1 metal ABC transporter solute-binding protein, Zn/Mn family -
  LLUC147_RS11140 (LLUC147_11175) - 2184013..2184450 (-) 438 WP_011677180.1 zinc-dependent MarR family transcriptional regulator -
  LLUC147_RS11145 (LLUC147_11180) comGG 2184530..2184757 (-) 228 WP_228764408.1 competence protein ComGG Machinery gene
  LLUC147_RS11150 (LLUC147_11185) comGF 2184853..2185299 (-) 447 WP_011836043.1 competence type IV pilus minor pilin ComGF Machinery gene
  LLUC147_RS11155 (LLUC147_11190) comGE 2185262..2185558 (-) 297 WP_021164977.1 competence type IV pilus minor pilin ComGE Machinery gene
  LLUC147_RS11160 (LLUC147_11195) comGD 2185530..2185718 (-) 189 WP_014573336.1 hypothetical protein Machinery gene
  LLUC147_RS11165 (LLUC147_11200) comGC 2185920..2186297 (-) 378 Protein_2174 competence type IV pilus major pilin ComGC -
  LLUC147_RS11170 (LLUC147_11205) comGB 2186315..2187340 (-) 1026 WP_050574185.1 competence type IV pilus assembly protein ComGB Machinery gene
  LLUC147_RS11175 (LLUC147_11210) comGA 2187240..2188220 (-) 981 WP_162494683.1 competence type IV pilus ATPase ComGA Machinery gene
  LLUC147_RS11180 (LLUC147_11215) - 2188335..2192117 (-) 3783 Protein_2177 PolC-type DNA polymerase III -

Sequence

Protein


Download         Length: 326 a.a.        Molecular weight: 37019.32 Da        Isoelectric Point: 5.9464

>NTDB_id=805806 LLUC147_RS11175 WP_162494683.1 2187240..2188220(-) (comGA) [Lactococcus cremoris strain UC147]
MVQKKAQELIQKAIEMEASDIYLIASGNLYKIYIRQQLGRTLIEELNQEIGLALLTHFKFLAGMNTGERRRVQLGACWYE
LEGSSAKRLRLSTVGDFEGNESLVIRLLHDQKQELEFWFDDKLQDFRCKRGLYLFSGPVGSGKTSLMFDLAHRHFSNAQV
ITIEEPVELIESDFIQLQVNDVIGNSYDELIKLSLRHRPDLLIVGEIRDQQTARAVLRASLTGYTVFSTIHAASVKGVVQ
RLLELGLSDWELKNGLEAVVYQRLIAGKGVLDIAKSKFDTWSPKKWNEKIENLYANGHLTAIEAEREKISINQASKIDTT
DGESFE

Nucleotide


Download         Length: 981 bp        

>NTDB_id=805806 LLUC147_RS11175 WP_162494683.1 2187240..2188220(-) (comGA) [Lactococcus cremoris strain UC147]
ATGGTACAGAAAAAAGCACAAGAACTCATTCAAAAGGCAATTGAGATGGAGGCTTCTGATATTTATTTAATTGCTTCAGG
AAATCTTTATAAGATATATATTCGTCAACAATTAGGGCGAACTTTAATAGAGGAACTTAACCAAGAGATTGGTTTAGCAT
TACTTACTCATTTTAAATTTCTTGCTGGCATGAATACTGGTGAACGCCGGCGTGTTCAGCTGGGTGCTTGTTGGTATGAA
CTAGAGGGAAGTTCGGCAAAACGTTTGCGCCTTTCAACAGTGGGAGATTTTGAAGGAAATGAATCATTGGTTATCCGTCT
TTTGCATGACCAAAAACAAGAACTTGAGTTTTGGTTTGACGATAAACTTCAGGATTTTCGATGTAAACGAGGACTTTATT
TATTTTCTGGGCCAGTAGGGTCTGGGAAAACTTCACTAATGTTTGACTTAGCCCACCGTCATTTTTCAAATGCACAGGTT
ATCACTATTGAGGAGCCTGTAGAATTAATTGAATCTGATTTTATTCAGTTACAAGTTAATGATGTAATTGGGAATAGTTA
TGATGAATTAATTAAACTTTCTTTAAGACACCGACCAGATTTACTAATTGTTGGAGAAATTCGAGATCAGCAGACAGCTC
GTGCTGTATTGCGTGCAAGTTTAACAGGCTATACAGTTTTTTCTACTATCCATGCGGCTTCCGTGAAGGGAGTGGTTCAA
CGTTTGTTGGAATTGGGTTTGAGTGATTGGGAATTGAAAAATGGATTAGAGGCAGTTGTTTATCAACGGTTAATAGCGGG
AAAAGGAGTATTAGATATTGCGAAAAGTAAATTTGACACTTGGTCGCCGAAAAAATGGAATGAAAAGATTGAGAACTTAT
ATGCAAACGGACATCTTACGGCTATTGAGGCCGAAAGGGAAAAAATTAGCATTAATCAAGCAAGCAAAATTGATACAACT
GATGGGGAATCTTTTGAATAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Lactococcus lactis subsp. cremoris KW2

99.08

100

0.991
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

56.452

95.092

0.537
  comYA Streptococcus gordonii str. Challis substr. CH1

54.43

96.933

0.528
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

54.487

95.706

0.521
  comGA/cglA/cilD Streptococcus pneumoniae D39

54.487

95.706

0.521
  comGA/cglA/cilD Streptococcus pneumoniae R6

54.487

95.706

0.521
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

54.487

95.706

0.521
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

54.487

95.706

0.521
  comYA Streptococcus mutans UA159

52.733

95.399

0.503
  comYA Streptococcus mutans UA140

52.733

95.399

0.503