Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   LLUC147_RS11155 Genome accession   NZ_CP120473
Coordinates   2185262..2185558 (-) Length   98 a.a.
NCBI ID   WP_021164977.1    Uniprot ID   A0A2Z5Z499
Organism   Lactococcus cremoris strain UC147     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2179990..2184450 2185262..2185558 flank 812


Gene organization within MGE regions


Location: 2179990..2185558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC147_RS11125 (LLUC147_11160) - 2181456..2182265 (-) 810 WP_011677177.1 metal ABC transporter permease -
  LLUC147_RS11130 (LLUC147_11165) - 2182258..2182995 (-) 738 WP_011677178.1 metal ABC transporter ATP-binding protein -
  LLUC147_RS11135 (LLUC147_11170) - 2183174..2184016 (-) 843 WP_011677179.1 metal ABC transporter solute-binding protein, Zn/Mn family -
  LLUC147_RS11140 (LLUC147_11175) - 2184013..2184450 (-) 438 WP_011677180.1 zinc-dependent MarR family transcriptional regulator -
  LLUC147_RS11145 (LLUC147_11180) comGG 2184530..2184757 (-) 228 WP_228764408.1 competence protein ComGG Machinery gene
  LLUC147_RS11150 (LLUC147_11185) comGF 2184853..2185299 (-) 447 WP_011836043.1 competence type IV pilus minor pilin ComGF Machinery gene
  LLUC147_RS11155 (LLUC147_11190) comGE 2185262..2185558 (-) 297 WP_021164977.1 competence type IV pilus minor pilin ComGE Machinery gene

Sequence

Protein


Download         Length: 98 a.a.        Molecular weight: 10958.72 Da        Isoelectric Point: 5.0658

>NTDB_id=805803 LLUC147_RS11155 WP_021164977.1 2185262..2185558(-) (comGE) [Lactococcus cremoris strain UC147]
MENIKRKSIKGCILLESLISMALLSFLVTFLLSALTNSRQQEVQENQQIESLNVAQMAIESQLMELSLNGSVIKIRQDST
ATIISDHGKEILRLEAQN

Nucleotide


Download         Length: 297 bp        

>NTDB_id=805803 LLUC147_RS11155 WP_021164977.1 2185262..2185558(-) (comGE) [Lactococcus cremoris strain UC147]
GTGGAAAATATAAAAAGAAAATCAATTAAGGGATGTATACTTCTTGAGAGCCTAATTAGTATGGCATTATTGAGCTTTTT
GGTCACTTTTCTCTTAAGTGCTCTTACTAATTCTCGTCAGCAAGAGGTACAAGAAAATCAACAAATTGAGTCCTTAAATG
TAGCTCAGATGGCAATAGAAAGTCAGCTGATGGAACTATCGTTAAATGGTTCTGTTATAAAAATAAGACAAGATTCGACT
GCAACCATTATTAGTGACCATGGAAAGGAAATTTTGCGACTTGAAGCTCAAAATTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5Z499

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

95.918

100

0.959