Detailed information NTG0805805

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: LLUC147_RS11170
• Genome accession: NZ_CP120473
• Coordinates: 2186315..2187340 (-)
• Length: 341 a.a.
• NCBI ID: WP_050574185.1
• Uniprot ID: -
• Organism: Lactococcus cremoris strain UC147
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2181315..2192340

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC147_RS11125 (LLUC147_11160)	-	2181456..2182265 (-)	810	WP_011677177.1	metal ABC transporter permease	-
LLUC147_RS11130 (LLUC147_11165)	-	2182258..2182995 (-)	738	WP_011677178.1	metal ABC transporter ATP-binding protein	-
LLUC147_RS11135 (LLUC147_11170)	-	2183174..2184016 (-)	843	WP_011677179.1	metal ABC transporter solute-binding protein, Zn/Mn family	-
LLUC147_RS11140 (LLUC147_11175)	-	2184013..2184450 (-)	438	WP_011677180.1	zinc-dependent MarR family transcriptional regulator	-
LLUC147_RS11145 (LLUC147_11180)	comGG	2184530..2184757 (-)	228	WP_228764408.1	competence protein ComGG	Machinery gene
LLUC147_RS11150 (LLUC147_11185)	comGF	2184853..2185299 (-)	447	WP_011836043.1	competence type IV pilus minor pilin ComGF	Machinery gene
LLUC147_RS11155 (LLUC147_11190)	comGE	2185262..2185558 (-)	297	WP_021164977.1	competence type IV pilus minor pilin ComGE	Machinery gene
LLUC147_RS11160 (LLUC147_11195)	comGD	2185530..2185718 (-)	189	WP_014573336.1	hypothetical protein	Machinery gene
LLUC147_RS11165 (LLUC147_11200)	comGC	2185920..2186297 (-)	378	Protein_2174	competence type IV pilus major pilin ComGC	-
LLUC147_RS11170 (LLUC147_11205)	comGB	2186315..2187340 (-)	1026	WP_050574185.1	competence type IV pilus assembly protein ComGB	Machinery gene
LLUC147_RS11175 (LLUC147_11210)	comGA	2187240..2188220 (-)	981	WP_162494683.1	competence type IV pilus ATPase ComGA	Machinery gene
LLUC147_RS11180 (LLUC147_11215)	-	2188335..2192117 (-)	3783	Protein_2177	PolC-type DNA polymerase III	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 38393.18 Da
• Isoelectric Point: 9.9840

>NTDB_id=805805 LLUC147_RS11170 WP_050574185.1 2186315..2187340(-) (comGB) [Lactococcus cremoris strain UC147]
MQTDILRLLRPKGKKLALIKQAKLIQLMGNLLNNGFHLGEVINFLALSKLVEKEFVFKMHQGLSSGNSLSEILDSLSCSK
NVVTQLALVEVHGNLVGTMQLVELHLKKQLKVKKKLIEVATYPVVLLVFLIGIMWGLKNYLLPQIDKGNNFATLLINHLP
LVFFSVGALIVLLTSLSIIIFKHLSALTNFTFLVKVPLVSSFIRLYLTAYFSREWGNLIAQGVELRQIIELMKKQKIRIF
AEVGIKLDLGLKAGQNFEQAVSHFSIFLPELSLMIEYGAIKDKLGLELSVYADECWEQFFSKIDRLMQLIQPLIFIFVAL
MIVLLYAAMSLPIYSNMGSGI

Nucleotide

• Length: 1026 bp

>NTDB_id=805805 LLUC147_RS11170 WP_050574185.1 2186315..2187340(-) (comGB) [Lactococcus cremoris strain UC147]
ATGCAAACGGACATCTTACGGCTATTGAGGCCGAAAGGGAAAAAATTAGCATTAATCAAGCAAGCAAAATTGATACAACT
GATGGGGAATCTTTTGAATAATGGTTTCCATTTGGGAGAAGTTATCAATTTTTTAGCTTTATCAAAATTAGTAGAAAAAG
AGTTTGTATTCAAAATGCACCAAGGTCTCAGTTCTGGAAATTCATTATCTGAAATTTTAGATAGTCTCTCTTGTTCTAAA
AATGTTGTGACACAACTTGCTTTGGTAGAAGTGCATGGGAATTTAGTAGGAACCATGCAATTGGTAGAACTGCATTTAAA
AAAGCAGCTTAAGGTCAAAAAGAAATTAATTGAAGTGGCAACTTATCCAGTTGTATTGTTGGTATTTCTCATTGGAATTA
TGTGGGGCTTGAAAAATTATTTATTACCTCAAATTGATAAGGGAAATAATTTTGCTACTTTATTAATTAATCATTTACCG
CTAGTATTTTTTTCTGTTGGTGCTTTAATCGTTTTACTGACAAGTTTATCAATAATAATATTCAAACATCTTTCAGCACT
CACTAATTTTACTTTTTTGGTTAAAGTTCCATTAGTAAGTTCTTTTATCCGCTTGTATTTGACCGCTTATTTCTCCAGAG
AATGGGGAAATTTAATTGCTCAAGGAGTTGAATTGCGACAAATAATAGAATTGATGAAAAAGCAGAAAATTCGCATTTTT
GCGGAAGTTGGAATTAAACTTGATTTGGGTTTGAAGGCTGGTCAGAATTTTGAGCAAGCTGTCAGTCATTTTTCGATTTT
TTTACCAGAACTTTCTTTGATGATTGAGTACGGCGCGATTAAAGATAAATTAGGGTTGGAGCTTTCTGTTTATGCTGATG
AATGTTGGGAACAATTCTTTTCTAAGATAGACCGTCTAATGCAATTAATACAACCCCTTATTTTTATTTTTGTTGCTTTG
ATGATTGTCTTATTGTATGCAGCGATGTCGTTACCCATTTATTCTAATATGGGTTCTGGAATTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (211-332)

• Type II secretion system (T2SS), protein F (T2SSF) (25-143)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Lactococcus lactis subsp. cremoris KW2	97.654	100	0.977
comYB	Streptococcus gordonii str. Challis substr. CH1	51.039	98.827	0.504
comGB/cglB	Streptococcus pneumoniae D39	50.299	97.947	0.493
comGB/cglB	Streptococcus pneumoniae R6	50.299	97.947	0.493
comGB/cglB	Streptococcus pneumoniae Rx1	50.299	97.947	0.493
comGB/cglB	Streptococcus pneumoniae TIGR4	50.299	97.947	0.493
comGB/cglB	Streptococcus mitis SK321	50	97.947	0.49
comGB/cglB	Streptococcus mitis NCTC 12261	49.102	97.947	0.481
comYB	Streptococcus mutans UA140	50.955	92.082	0.469
comYB	Streptococcus mutans UA159	50.318	92.082	0.463