Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   PW220_RS00690 Genome accession   NZ_CP118734
Coordinates   108648..109607 (+) Length   319 a.a.
NCBI ID   WP_248055938.1    Uniprot ID   A0AA96VJB9
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 103648..114607
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS00680 (PW220_00680) - 107215..107592 (+) 378 WP_172049590.1 DUF1033 family protein -
  PW220_RS00685 (PW220_00685) - 107613..108563 (-) 951 WP_248049579.1 S66 family peptidase -
  PW220_RS00690 (PW220_00690) comYA 108648..109607 (+) 960 WP_248055938.1 competence type IV pilus ATPase ComGA Machinery gene
  PW220_RS00695 (PW220_00695) comYB 109510..110547 (+) 1038 WP_316716460.1 competence type IV pilus assembly protein ComGB Machinery gene
  PW220_RS00700 (PW220_00700) comYC 110549..110830 (+) 282 WP_105096850.1 competence type IV pilus major pilin ComGC Machinery gene
  PW220_RS00705 (PW220_00705) comGD 110811..111218 (+) 408 WP_248055939.1 competence type IV pilus minor pilin ComGD -
  PW220_RS00710 (PW220_00710) comYE 111190..111483 (+) 294 WP_105117571.1 competence type IV pilus minor pilin ComGE Machinery gene
  PW220_RS00715 (PW220_00715) comGF/cglF 111470..111904 (+) 435 WP_105117572.1 competence type IV pilus minor pilin ComGF Machinery gene
  PW220_RS00720 (PW220_00720) comGG 111882..112397 (+) 516 WP_248055940.1 competence type IV pilus minor pilin ComGG -

Sequence

Protein


Download         Length: 319 a.a.        Molecular weight: 35832.61 Da        Isoelectric Point: 5.8535

>NTDB_id=794664 PW220_RS00690 WP_248055938.1 108648..109607(+) (comYA) [Streptococcus iners subsp. hyiners strain 29892]
MIQEKARKLIEEAVADRVSDIYLVPRGQDYQVYHRIMDEREFVHDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGNGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSSEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKITLGSPAYGH

Nucleotide


Download         Length: 960 bp        

>NTDB_id=794664 PW220_RS00690 WP_248055938.1 108648..109607(+) (comYA) [Streptococcus iners subsp. hyiners strain 29892]
ATGATTCAAGAAAAAGCAAGAAAGTTGATTGAAGAGGCGGTGGCGGATAGGGTCAGTGATATTTATCTGGTTCCTCGTGG
TCAGGACTACCAAGTCTACCATCGCATCATGGACGAACGGGAGTTTGTGCACGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTCTTAGCAGGTTTAAATGTCGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAACGGCGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCTGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACTATCGAGGATCCTGTCGAAATCAAGCAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTCCATGCAAGGTCTATTTCAGGTGTCTAC
GCCCGTATGTTGGAATTGGGTGTCAGCTCTGAGGAGTTAAACAATGCCCTTCAAGGTATTGCCTATCAACGTTTAATAGG
GGGAGGAGGTGTGGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTACCCTTGGTTCGCCAGCGTACGGTCATTGA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.387

97.179

0.665
  comYA Streptococcus mutans UA159

67.846

97.492

0.661
  comYA Streptococcus mutans UA140

67.846

97.492

0.661
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.273

97.492

0.636
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

97.492

0.636
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.273

97.492

0.636
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.273

97.492

0.636
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.273

97.492

0.636
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

97.179

0.63
  comGA Lactococcus lactis subsp. cremoris KW2

53.312

99.373

0.53