Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   PW220_RS00695 Genome accession   NZ_CP118734
Coordinates   109510..110547 (+) Length   345 a.a.
NCBI ID   WP_316716460.1    Uniprot ID   A0AA96VHN5
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 104510..115547
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS00680 (PW220_00680) - 107215..107592 (+) 378 WP_172049590.1 DUF1033 family protein -
  PW220_RS00685 (PW220_00685) - 107613..108563 (-) 951 WP_248049579.1 S66 family peptidase -
  PW220_RS00690 (PW220_00690) comYA 108648..109607 (+) 960 WP_248055938.1 competence type IV pilus ATPase ComGA Machinery gene
  PW220_RS00695 (PW220_00695) comYB 109510..110547 (+) 1038 WP_316716460.1 competence type IV pilus assembly protein ComGB Machinery gene
  PW220_RS00700 (PW220_00700) comYC 110549..110830 (+) 282 WP_105096850.1 competence type IV pilus major pilin ComGC Machinery gene
  PW220_RS00705 (PW220_00705) comGD 110811..111218 (+) 408 WP_248055939.1 competence type IV pilus minor pilin ComGD -
  PW220_RS00710 (PW220_00710) comYE 111190..111483 (+) 294 WP_105117571.1 competence type IV pilus minor pilin ComGE Machinery gene
  PW220_RS00715 (PW220_00715) comGF/cglF 111470..111904 (+) 435 WP_105117572.1 competence type IV pilus minor pilin ComGF Machinery gene
  PW220_RS00720 (PW220_00720) comGG 111882..112397 (+) 516 WP_248055940.1 competence type IV pilus minor pilin ComGG -
  PW220_RS00725 (PW220_00725) atlA 112636..114711 (+) 2076 WP_248055941.1 autolysin AtlA -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 39042.01 Da        Isoelectric Point: 8.8008

>NTDB_id=794665 PW220_RS00695 WP_316716460.1 109510..110547(+) (comYB) [Streptococcus iners subsp. hyiners strain 29892]
MRKLIAFLQQDISVFGRQKQKKLPLVRQRTVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLHFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPVILLGFLLLIMLGLKNYLLPQLEEGNVATV
LINHLPTIFLSLCGLSLVAVLAGLVWFRKTDKIKVFSRLVALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEEFFSRVNRAMHLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=794665 PW220_RS00695 WP_316716460.1 109510..110547(+) (comYB) [Streptococcus iners subsp. hyiners strain 29892]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTACCCTTGGTTCG
CCAGCGTACGGTCATTGAACTGTTTAATAATCTCTTTGCCAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTGCTGGCAGATCCCTATACCCAGGTCTTGTCGGATGGTCTTCTTGCAGGCAAACCCTTTTCAAGTTTGCTG
GCGGATTTGCATTTTTCAGATGCGGTGGTCACACAGGTGGCTTTGGCAGAAGTTCATGGCAATACCAGTCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAAGTAGCGACCTATCCAGTTATCTTGC
TTGGTTTTCTGCTTTTGATTATGCTTGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAACGTAGCGACCGTG
CTAATTAACCATCTGCCGACTATCTTTTTATCCCTTTGTGGACTTAGTTTGGTAGCGGTCTTAGCTGGTCTTGTTTGGTT
TCGCAAAACCGATAAAATCAAAGTCTTTTCCCGTTTAGTAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTACCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCCTGATGCAGGAG
CAACAATCGCAGCTCTTTCGGGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
CAAGACCTACGCCTTTTTTAAGCGGGAGTTGAGTTTGATTGTCGAGTACGGTCAGGTCAAGTCCAAATTAGGGAGCGAGT
TGACAGTCTATGCAGCTGAGTGTTGGGAGGAATTTTTCTCTCGGGTCAATAGAGCCATGCATCTAATCCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.743

99.13

0.632
  comGB/cglB Streptococcus mitis NCTC 12261

60.597

97.101

0.588
  comGB/cglB Streptococcus mitis SK321

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae D39

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae Rx1

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae R6

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae TIGR4

60

97.101

0.583
  comYB Streptococcus mutans UA140

58.309

99.42

0.58
  comYB Streptococcus mutans UA159

58.309

99.42

0.58
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493