Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   PW220_RS00715 Genome accession   NZ_CP118734
Coordinates   111470..111904 (+) Length   144 a.a.
NCBI ID   WP_105117572.1    Uniprot ID   -
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 106470..116904
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS00680 (PW220_00680) - 107215..107592 (+) 378 WP_172049590.1 DUF1033 family protein -
  PW220_RS00685 (PW220_00685) - 107613..108563 (-) 951 WP_248049579.1 S66 family peptidase -
  PW220_RS00690 (PW220_00690) comYA 108648..109607 (+) 960 WP_248055938.1 competence type IV pilus ATPase ComGA Machinery gene
  PW220_RS00695 (PW220_00695) comYB 109510..110547 (+) 1038 WP_316716460.1 competence type IV pilus assembly protein ComGB Machinery gene
  PW220_RS00700 (PW220_00700) comYC 110549..110830 (+) 282 WP_105096850.1 competence type IV pilus major pilin ComGC Machinery gene
  PW220_RS00705 (PW220_00705) comGD 110811..111218 (+) 408 WP_248055939.1 competence type IV pilus minor pilin ComGD -
  PW220_RS00710 (PW220_00710) comYE 111190..111483 (+) 294 WP_105117571.1 competence type IV pilus minor pilin ComGE Machinery gene
  PW220_RS00715 (PW220_00715) comGF/cglF 111470..111904 (+) 435 WP_105117572.1 competence type IV pilus minor pilin ComGF Machinery gene
  PW220_RS00720 (PW220_00720) comGG 111882..112397 (+) 516 WP_248055940.1 competence type IV pilus minor pilin ComGG -
  PW220_RS00725 (PW220_00725) atlA 112636..114711 (+) 2076 WP_248055941.1 autolysin AtlA -
  PW220_RS00730 (PW220_00730) - 114965..115768 (+) 804 WP_105117575.1 ABC transporter permease -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16455.78 Da        Isoelectric Point: 8.0041

>NTDB_id=794668 PW220_RS00715 WP_105117572.1 111470..111904(+) (comGF/cglF) [Streptococcus iners subsp. hyiners strain 29892]
MLKSKIPAFTLLECLVALVILSGSLLVFEGLSKLLVQEAHYQRHTIQKEWQVFSSQLRSEWDQADLVKVENGKVYVDKAG
QALAFGKSRSDDFRKTNDRGQGYQPMLYQVDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKG

Nucleotide


Download         Length: 435 bp        

>NTDB_id=794668 PW220_RS00715 WP_105117572.1 111470..111904(+) (comGF/cglF) [Streptococcus iners subsp. hyiners strain 29892]
TTGTTAAAAAGTAAAATTCCTGCCTTTACTCTCCTGGAATGCTTGGTAGCCTTAGTCATCCTTTCAGGTAGCCTTTTGGT
CTTTGAAGGCTTGTCAAAACTGCTGGTCCAAGAAGCGCATTACCAAAGGCATACCATACAGAAGGAATGGCAGGTCTTTT
CTAGCCAGTTGCGGTCGGAGTGGGACCAGGCGGACTTGGTCAAGGTTGAAAATGGCAAGGTCTATGTAGACAAGGCTGGT
CAGGCTTTGGCCTTTGGTAAGTCACGGTCGGATGATTTTCGGAAAACAAATGACAGGGGACAGGGCTACCAGCCCATGCT
CTATCAGGTGGACAGCGCAGCCATTTCCCAAGAAAACCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGGGAGGAGC
GGACCTTTATCTATGCTTTTAAAGAAAAAGGTTAG

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(38-134)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus mitis NCTC 12261

52.985

93.056

0.493
  comYF Streptococcus mutans UA140

49.65

99.306

0.493
  comGF/cglF Streptococcus pneumoniae D39

52.239

93.056

0.486
  comGF/cglF Streptococcus pneumoniae R6

52.239

93.056

0.486
  comGF/cglF Streptococcus pneumoniae TIGR4

52.239

93.056

0.486
  comGF/cglF Streptococcus pneumoniae Rx1

52.239

93.056

0.486
  comYF Streptococcus mutans UA159

48.951

99.306

0.486
  comGF Lactococcus lactis subsp. cremoris KW2

47.518

97.917

0.465
  comGF/cglF Streptococcus mitis SK321

50

93.056

0.465