Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   PE069_RS04365 Genome accession   NZ_CP115992
Coordinates   914017..914292 (-) Length   91 a.a.
NCBI ID   WP_002356991.1    Uniprot ID   A0A1B4XPV0
Organism   Enterococcus faecalis strain ESC1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 909017..919292
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PE069_RS04325 (PE069_04325) - 909062..909394 (+) 333 WP_002357068.1 hypothetical protein -
  PE069_RS04330 (PE069_04330) - 909572..910045 (+) 474 WP_002357065.1 universal stress protein -
  PE069_RS04335 (PE069_04335) - 910157..911344 (-) 1188 WP_002357064.1 acetate/propionate family kinase -
  PE069_RS04340 (PE069_04340) - 911369..912376 (-) 1008 WP_002357063.1 class I SAM-dependent methyltransferase -
  PE069_RS04345 (PE069_04345) comGG 912505..912858 (-) 354 WP_016618446.1 competence type IV pilus minor pilin ComGG -
  PE069_RS04350 (PE069_04350) comGF 912858..913292 (-) 435 WP_010707381.1 competence type IV pilus minor pilin ComGF -
  PE069_RS04355 (PE069_04355) - 913282..913608 (-) 327 WP_010775953.1 type II secretion system protein -
  PE069_RS04360 (PE069_04360) comGD 913574..914020 (-) 447 WP_016618445.1 competence type IV pilus minor pilin ComGD -
  PE069_RS04365 (PE069_04365) comGC/cglC 914017..914292 (-) 276 WP_002356991.1 competence type IV pilus major pilin ComGC Machinery gene
  PE069_RS04370 (PE069_04370) comGB 914292..915338 (-) 1047 WP_104846628.1 competence type IV pilus assembly protein ComGB -
  PE069_RS04375 (PE069_04375) comGA 915295..916263 (-) 969 WP_085443259.1 competence type IV pilus ATPase ComGA -
  PE069_RS04380 (PE069_04380) - 916503..917831 (-) 1329 WP_064687249.1 APC family permease -
  PE069_RS04385 (PE069_04385) rlmN 918121..919194 (-) 1074 WP_002356987.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -

Sequence


Protein


Download         Length: 91 a.a.        Molecular weight: 10464.41 Da        Isoelectric Point: 9.3192

>NTDB_id=774779 PE069_RS04365 WP_002356991.1 914017..914292(-) (comGC/cglC) [Enterococcus faecalis strain ESC1]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ

Nucleotide


Download         Length: 276 bp        

>NTDB_id=774779 PE069_RS04365 WP_002356991.1 914017..914292(-) (comGC/cglC) [Enterococcus faecalis strain ESC1]
ATGAAAAAGAAACAAAAATACGCGGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTCCCTAACTTAGCGAAACATAAAGAAACAGTTGACAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCCTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A1B4XPV0

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae D39

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae R6

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae TIGR4

63.095

92.308

0.582

  comGC/cglC Streptococcus mitis NCTC 12261

61.905

92.308

0.571

  comGC/cglC Streptococcus mitis SK321

61.176

93.407

0.571

  comGC Lactococcus lactis subsp. cremoris KW2

58.14

94.505

0.549

  comYC Streptococcus gordonii str. Challis substr. CH1

56.322

95.604

0.538

  comYC Streptococcus suis isolate S10

52.326

94.505

0.495

  comYC Streptococcus mutans UA159

57.692

85.714

0.495

  comYC Streptococcus mutans UA140

57.692

85.714

0.495

  comGC Latilactobacillus sakei subsp. sakei 23K

46.154

100

0.462

  comGC Staphylococcus aureus MW2

46.835

86.813

0.407

  comGC Staphylococcus aureus N315

46.835

86.813

0.407

  comGC Bacillus subtilis subsp. subtilis str. 168

48.649

81.319

0.396