Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   OLL95_RS07255 Genome accession   NZ_CP110054
Coordinates   1489834..1490109 (+) Length   91 a.a.
NCBI ID   WP_002356991.1    Uniprot ID   A0A1B4XPV0
Organism   Enterococcus faecalis strain BE17     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1490133..1528665 1489834..1490109 flank 24


Gene organization within MGE regions


Location: 1489834..1528665
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OLL95_RS07255 (OLL95_07255) comGC/cglC 1489834..1490109 (+) 276 WP_002356991.1 competence type IV pilus major pilin ComGC Machinery gene
  OLL95_RS07260 (OLL95_07260) comGD 1490106..1490540 (+) 435 Protein_1413 competence type IV pilus minor pilin ComGD -
  OLL95_RS07265 (OLL95_07265) - 1490577..1491725 (-) 1149 WP_002378469.1 site-specific integrase -
  OLL95_RS07270 (OLL95_07270) - 1491825..1492553 (-) 729 WP_002381717.1 potassium channel family protein -
  OLL95_RS07275 (OLL95_07275) - 1492589..1492933 (-) 345 WP_002378467.1 ImmA/IrrE family metallo-endopeptidase -
  OLL95_RS07280 (OLL95_07280) - 1492950..1493282 (-) 333 WP_002364355.1 helix-turn-helix domain-containing protein -
  OLL95_RS07285 (OLL95_07285) - 1493594..1493770 (+) 177 WP_002364354.1 helix-turn-helix transcriptional regulator -
  OLL95_RS07290 (OLL95_07290) - 1493781..1494092 (+) 312 WP_002381719.1 hypothetical protein -
  OLL95_RS07295 (OLL95_07295) - 1494131..1494853 (+) 723 WP_002410531.1 Rha family transcriptional regulator -
  OLL95_RS07300 (OLL95_07300) - 1494879..1495067 (-) 189 WP_002357001.1 YegP family protein -
  OLL95_RS07305 (OLL95_07305) - 1495122..1495331 (+) 210 WP_002378465.1 hypothetical protein -
  OLL95_RS07310 (OLL95_07310) - 1495368..1495706 (+) 339 WP_002402484.1 hypothetical protein -
  OLL95_RS07315 (OLL95_07315) - 1495902..1496219 (+) 318 WP_002402485.1 hypothetical protein -
  OLL95_RS07320 (OLL95_07320) - 1496212..1496946 (+) 735 WP_002402486.1 ERF family protein -
  OLL95_RS07325 (OLL95_07325) - 1496951..1497592 (+) 642 WP_002402487.1 putative HNHc nuclease -
  OLL95_RS07330 (OLL95_07330) - 1497597..1497797 (+) 201 WP_010715320.1 hypothetical protein -
  OLL95_RS07335 (OLL95_07335) - 1497797..1498657 (+) 861 WP_002402489.1 helix-turn-helix domain-containing protein -
  OLL95_RS07340 (OLL95_07340) - 1498654..1498956 (+) 303 WP_002368214.1 hypothetical protein -
  OLL95_RS07345 (OLL95_07345) - 1498957..1499256 (+) 300 WP_002402490.1 MazG-like family protein -
  OLL95_RS07350 (OLL95_07350) - 1499265..1499699 (+) 435 WP_002402491.1 RusA family crossover junction endodeoxyribonuclease -
  OLL95_RS07355 (OLL95_07355) - 1500606..1501022 (+) 417 WP_010785402.1 ArpU family phage packaging/lysis transcriptional regulator -
  OLL95_RS07365 (OLL95_07365) - 1501553..1502053 (+) 501 WP_264547743.1 hypothetical protein -
  OLL95_RS07370 (OLL95_07370) - 1502864..1503094 (+) 231 Protein_1434 hypothetical protein -
  OLL95_RS07375 (OLL95_07375) - 1503126..1503560 (+) 435 WP_002364295.1 terminase small subunit -
  OLL95_RS07380 (OLL95_07380) - 1503541..1504824 (+) 1284 WP_002402493.1 PBSX family phage terminase large subunit -
  OLL95_RS07385 (OLL95_07385) - 1504824..1506308 (+) 1485 WP_010822970.1 phage portal protein -
  OLL95_RS07390 (OLL95_07390) - 1506301..1507227 (+) 927 WP_002378457.1 minor capsid protein -
  OLL95_RS07395 (OLL95_07395) - 1507350..1507985 (+) 636 WP_010785401.1 DUF4355 domain-containing protein -
  OLL95_RS07400 (OLL95_07400) - 1507999..1508895 (+) 897 WP_002363368.1 hypothetical protein -
  OLL95_RS07405 (OLL95_07405) - 1508966..1509298 (+) 333 WP_002363369.1 phage head-tail connector protein -
  OLL95_RS07410 (OLL95_07410) - 1509295..1509570 (+) 276 WP_002364301.1 hypothetical protein -
  OLL95_RS07415 (OLL95_07415) - 1509567..1509905 (+) 339 WP_002363372.1 HK97-gp10 family putative phage morphogenesis protein -
  OLL95_RS07420 (OLL95_07420) - 1509902..1510294 (+) 393 WP_002363373.1 DUF3168 domain-containing protein -
  OLL95_RS07425 (OLL95_07425) - 1510313..1510918 (+) 606 WP_002364302.1 phage major tail protein, TP901-1 family -
  OLL95_RS07430 (OLL95_07430) - 1510921..1511103 (+) 183 WP_002378453.1 hypothetical protein -
  OLL95_RS07435 (OLL95_07435) - 1511152..1511724 (+) 573 WP_002402496.1 immunoglobulin-like domain-containing protein -
  OLL95_RS07440 (OLL95_07440) - 1511778..1512176 (+) 399 WP_002402497.1 tail assembly chaperone -
  OLL95_RS07445 (OLL95_07445) - 1512245..1512550 (+) 306 WP_002402498.1 hypothetical protein -
  OLL95_RS07450 (OLL95_07450) - 1512537..1516991 (+) 4455 WP_002402500.1 phage tail tape measure protein -
  OLL95_RS07455 (OLL95_07455) - 1516988..1517710 (+) 723 WP_002402501.1 hypothetical protein -
  OLL95_RS07460 (OLL95_07460) - 1517710..1519155 (+) 1446 WP_002378447.1 phage tail spike protein -
  OLL95_RS07465 (OLL95_07465) - 1519161..1519901 (+) 741 WP_002363383.1 hypothetical protein -
  OLL95_RS07470 (OLL95_07470) - 1519918..1520370 (+) 453 WP_002363384.1 hypothetical protein -
  OLL95_RS07475 (OLL95_07475) - 1520389..1520784 (+) 396 WP_002363385.1 hypothetical protein -
  OLL95_RS07480 (OLL95_07480) - 1520786..1520908 (+) 123 WP_002368228.1 XkdX family protein -
  OLL95_RS07485 (OLL95_07485) - 1520919..1521299 (+) 381 WP_002378446.1 phage holin family protein -
  OLL95_RS07490 (OLL95_07490) - 1521312..1522571 (+) 1260 WP_002401959.1 LysM peptidoglycan-binding domain-containing protein -
  OLL95_RS07495 (OLL95_07495) - 1523425..1523625 (+) 201 WP_002357053.1 cold-shock protein -
  OLL95_RS07500 (OLL95_07500) - 1523697..1523969 (+) 273 WP_002378444.1 hypothetical protein -
  OLL95_RS07510 (OLL95_07510) hemH 1524684..1525625 (+) 942 WP_002357056.1 ferrochelatase -
  OLL95_RS07515 (OLL95_07515) - 1526381..1526752 (+) 372 WP_099704299.1 type II secretion system protein -
  OLL95_RS07520 (OLL95_07520) comGF 1526742..1527176 (+) 435 WP_002362055.1 competence type IV pilus minor pilin ComGF -
  OLL95_RS07525 (OLL95_07525) comGG 1527176..1527529 (+) 354 WP_002369174.1 competence type IV pilus minor pilin ComGG -
  OLL95_RS07530 (OLL95_07530) - 1527658..1528665 (+) 1008 WP_264547744.1 class I SAM-dependent methyltransferase -

Sequence


Protein


Download         Length: 91 a.a.        Molecular weight: 10464.41 Da        Isoelectric Point: 9.3192

>NTDB_id=751857 OLL95_RS07255 WP_002356991.1 1489834..1490109(+) (comGC/cglC) [Enterococcus faecalis strain BE17]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ

Nucleotide


Download         Length: 276 bp        

>NTDB_id=751857 OLL95_RS07255 WP_002356991.1 1489834..1490109(+) (comGC/cglC) [Enterococcus faecalis strain BE17]
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTTCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCTTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A1B4XPV0

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae D39

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae R6

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae TIGR4

63.095

92.308

0.582

  comGC/cglC Streptococcus mitis NCTC 12261

61.905

92.308

0.571

  comGC/cglC Streptococcus mitis SK321

61.176

93.407

0.571

  comGC Lactococcus lactis subsp. cremoris KW2

58.14

94.505

0.549

  comYC Streptococcus gordonii str. Challis substr. CH1

56.322

95.604

0.538

  comYC Streptococcus suis isolate S10

52.326

94.505

0.495

  comYC Streptococcus mutans UA159

57.692

85.714

0.495

  comYC Streptococcus mutans UA140

57.692

85.714

0.495

  comGC Latilactobacillus sakei subsp. sakei 23K

46.154

100

0.462

  comGC Staphylococcus aureus MW2

46.835

86.813

0.407

  comGC Staphylococcus aureus N315

46.835

86.813

0.407

  comGC Bacillus subtilis subsp. subtilis str. 168

48.649

81.319

0.396