Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   P8R98_RS11570 Genome accession   NZ_CP121159
Coordinates   2323602..2324573 (-) Length   323 a.a.
NCBI ID   WP_000250798.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain S1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2318602..2329573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8R98_RS11530 - 2318602..2319795 (-) 1194 WP_000047534.1 acetate kinase -
  P8R98_RS11535 comGH 2319827..2320801 (-) 975 WP_001008569.1 class I SAM-dependent methyltransferase Machinery gene
  P8R98_RS11540 comGG 2320916..2321287 (-) 372 WP_000601101.1 competence type IV pilus minor pilin ComGG Machinery gene
  P8R98_RS11545 comGF 2321265..2321726 (-) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF Machinery gene
  P8R98_RS11550 comGE 2321680..2321979 (-) 300 WP_001872488.1 competence type IV pilus minor pilin ComGE Machinery gene
  P8R98_RS11555 comGD 2321951..2322364 (-) 414 WP_000244259.1 competence type IV pilus minor pilin ComGD Machinery gene
  P8R98_RS11560 comGC/cglC 2322339..2322668 (-) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  P8R98_RS11565 comGB 2322665..2323708 (-) 1044 WP_223297804.1 competence type IV pilus assembly protein ComGB Machinery gene
  P8R98_RS11570 comGA 2323602..2324573 (-) 972 WP_000250798.1 competence type IV pilus ATPase ComGA Machinery gene
  P8R98_RS11575 - 2324619..2326080 (-) 1462 Protein_2210 IS1182-like element IS1563 family transposase -
  P8R98_RS11580 - 2326310..2326675 (-) 366 WP_000285374.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 323 a.a.        Molecular weight: 36768.25 Da        Isoelectric Point: 6.9167

>NTDB_id=736178 P8R98_RS11570 WP_000250798.1 2323602..2324573(-) (comGA) [Streptococcus agalactiae strain S1]
MVQSLAKHVIHQAVEVNAQDIYIIPKGDCYELYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRILYSGHQDLKYWFDNIKQMKEVLGARGLYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSIPGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETGNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF

Nucleotide


Download         Length: 972 bp        

>NTDB_id=736178 P8R98_RS11570 WP_000250798.1 2323602..2324573(-) (comGA) [Streptococcus agalactiae strain S1]
ATGGTTCAATCATTAGCAAAGCACGTCATCCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATCATTCCCAAAGG
TGATTGTTATGAACTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTGGTTTCATTACGACTATCAAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAT
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTGCAAGAGGGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTGATGGTTTTTTCTACTATTCATGCTAAAAGTATTCCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAGGTAATTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Streptococcus mutans UA159

68.81

96.285

0.663
  comGA Streptococcus mutans UA140

68.81

96.285

0.663
  comGA Streptococcus gordonii str. Challis substr. CH1

63.636

98.762

0.628
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.701

96.285

0.604
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.736

96.285

0.594
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

95.975

0.594
  comGA Lactococcus lactis subsp. cremoris KW2

50.621

99.69

0.505