Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   P8R98_RS11565 Genome accession   NZ_CP121159
Coordinates   2322665..2323708 (-) Length   347 a.a.
NCBI ID   WP_223297804.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain S1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2317665..2328708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8R98_RS11530 - 2318602..2319795 (-) 1194 WP_000047534.1 acetate kinase -
  P8R98_RS11535 comGH 2319827..2320801 (-) 975 WP_001008569.1 class I SAM-dependent methyltransferase Machinery gene
  P8R98_RS11540 comGG 2320916..2321287 (-) 372 WP_000601101.1 competence type IV pilus minor pilin ComGG Machinery gene
  P8R98_RS11545 comGF 2321265..2321726 (-) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF Machinery gene
  P8R98_RS11550 comGE 2321680..2321979 (-) 300 WP_001872488.1 competence type IV pilus minor pilin ComGE Machinery gene
  P8R98_RS11555 comGD 2321951..2322364 (-) 414 WP_000244259.1 competence type IV pilus minor pilin ComGD Machinery gene
  P8R98_RS11560 comGC/cglC 2322339..2322668 (-) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  P8R98_RS11565 comGB 2322665..2323708 (-) 1044 WP_223297804.1 competence type IV pilus assembly protein ComGB Machinery gene
  P8R98_RS11570 comGA 2323602..2324573 (-) 972 WP_000250798.1 competence type IV pilus ATPase ComGA Machinery gene
  P8R98_RS11575 - 2324619..2326080 (-) 1462 Protein_2210 IS1182-like element IS1563 family transposase -
  P8R98_RS11580 - 2326310..2326675 (-) 366 WP_000285374.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40014.77 Da        Isoelectric Point: 9.9642

>NTDB_id=736177 P8R98_RS11565 WP_223297804.1 2322665..2323708(-) (comGB) [Streptococcus agalactiae strain S1]
MDKWISWLKKDISVRNRHKSKKLSLKKQRKVVQLFNNLFASGFSLTDMVTFLKRSKLLSDCYTDRMNKALLEGKDLSKML
GELGFSDTVITQVALADLHGNISRSLLKIESYLANLLLVRKKVIEVATYPLILLSFLVLIMIGLRHYLMPQLGENNFATR
LITNVPNIFLLLLAVVLIFSLIFYIIQKRLSRIKVACFLTTIPLVGSYVKLYLTAYYAREWGNLLSQGVELDQIVKVMQN
QKSKLFREIGYDMEEGFLSGKAFHQKVLDYPFFLTELSLMIEYGQVKAKLGTELDIYADEKWEDFFTKLARATQLIQPVI
FIFVALIIVMIYAAMLLPMYQNMEILS

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=736177 P8R98_RS11565 WP_223297804.1 2322665..2323708(-) (comGB) [Streptococcus agalactiae strain S1]
ATAGACAAGTGGATATCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAA
ACAACGGAAAGTAGTCCAACTTTTTAATAATCTTTTTGCTAGTGGTTTTTCTTTAACTGATATGGTCACCTTCTTAAAGA
GGAGTAAGTTATTGTCTGATTGTTATACAGATAGGATGAATAAGGCATTATTAGAGGGAAAAGATTTATCAAAAATGTTA
GGAGAGTTAGGTTTTTCTGACACTGTTATCACACAGGTTGCATTAGCTGATTTGCATGGTAACATTTCAAGGAGCCTACT
AAAGATTGAGTCTTATTTAGCTAATCTTTTGTTAGTTAGAAAAAAAGTAATAGAAGTAGCTACTTACCCATTGATATTAT
TGTCTTTTCTGGTGCTAATTATGATTGGCCTTAGGCATTATTTAATGCCCCAATTAGGAGAAAATAATTTTGCAACTAGA
CTGATTACAAATGTGCCGAATATTTTCTTATTACTTTTAGCAGTTGTACTTATTTTTAGTTTAATATTTTATATTATTCA
AAAGCGATTGTCGCGCATTAAAGTAGCTTGTTTTTTAACAACAATTCCCTTAGTTGGATCATATGTTAAGCTTTATTTAA
CTGCTTACTATGCCCGTGAGTGGGGAAATTTATTAAGTCAAGGTGTTGAATTGGACCAAATTGTTAAAGTAATGCAAAAT
CAGAAATCCAAACTTTTTAGGGAAATAGGATATGACATGGAAGAAGGTTTTCTATCAGGTAAAGCATTTCACCAAAAAGT
ATTAGACTATCCGTTTTTCTTAACTGAGCTTAGTTTAATGATTGAATATGGTCAAGTTAAGGCGAAATTAGGAACAGAGT
TAGATATATATGCTGATGAGAAGTGGGAGGATTTTTTTACAAAATTAGCTAGAGCGACCCAGTTAATCCAACCTGTTATT
TTTATTTTTGTAGCTCTTATCATTGTTATGATTTATGCAGCAATGCTGTTACCAATGTATCAAAATATGGAGATATTATC
ATGA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Streptococcus mutans UA140

62.17

98.271

0.611
  comGB Streptococcus mutans UA159

61.877

98.271

0.608
  comGB Streptococcus gordonii str. Challis substr. CH1

56.012

98.271

0.55
  comGB/cglB Streptococcus mitis NCTC 12261

54.925

96.542

0.53
  comGB/cglB Streptococcus mitis SK321

54.328

96.542

0.524
  comGB/cglB Streptococcus pneumoniae Rx1

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae D39

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae R6

53.433

96.542

0.516
  comGB/cglB Streptococcus pneumoniae TIGR4

53.433

96.542

0.516
  comGB Lactococcus lactis subsp. cremoris KW2

50.148

97.118

0.487