Detailed information NTG0736173

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: P8R98_RS11545
• Genome accession: NZ_CP121159
• Coordinates: 2321265..2321726 (-)
• Length: 153 a.a.
• NCBI ID: WP_001874060.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain S1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2316265..2326726

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P8R98_RS11515	-	2316478..2316744 (-)	267	Protein_2198	hypothetical protein	-
P8R98_RS11520	-	2316723..2316915 (-)	193	Protein_2199	helix-turn-helix transcriptional regulator	-
P8R98_RS11525	-	2317113..2318643 (+)	1531	Protein_2200	IS1182-like element IS1563 family transposase	-
P8R98_RS11530	-	2318602..2319795 (-)	1194	WP_000047534.1	acetate kinase	-
P8R98_RS11535	comGH	2319827..2320801 (-)	975	WP_001008569.1	class I SAM-dependent methyltransferase	Machinery gene
P8R98_RS11540	comGG	2320916..2321287 (-)	372	WP_000601101.1	competence type IV pilus minor pilin ComGG	Machinery gene
P8R98_RS11545	comGF	2321265..2321726 (-)	462	WP_001874060.1	competence type IV pilus minor pilin ComGF	Machinery gene
P8R98_RS11550	comGE	2321680..2321979 (-)	300	WP_001872488.1	competence type IV pilus minor pilin ComGE	Machinery gene
P8R98_RS11555	comGD	2321951..2322364 (-)	414	WP_000244259.1	competence type IV pilus minor pilin ComGD	Machinery gene
P8R98_RS11560	comGC/cglC	2322339..2322668 (-)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
P8R98_RS11565	comGB	2322665..2323708 (-)	1044	WP_223297804.1	competence type IV pilus assembly protein ComGB	Machinery gene
P8R98_RS11570	comGA	2323602..2324573 (-)	972	WP_000250798.1	competence type IV pilus ATPase ComGA	Machinery gene
P8R98_RS11575	-	2324619..2326080 (-)	1462	Protein_2210	IS1182-like element IS1563 family transposase	-
P8R98_RS11580	-	2326310..2326675 (-)	366	WP_000285374.1	DUF1033 family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17861.86 Da
• Isoelectric Point: 9.8392

>NTDB_id=736173 P8R98_RS11545 WP_001874060.1 2321265..2321726(-) (comGF) [Streptococcus agalactiae strain S1]
MKVIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=736173 P8R98_RS11545 WP_001874060.1 2321265..2321726(-) (comGF) [Streptococcus agalactiae strain S1]
TTGAAGGTAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTGCTAGTTTATCAAGGACTAACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373