Detailed information
Bioinformatically predicted
Overview
| Name | comE/blpR | Type | Regulator |
| Locus tag | FNL60_RS01555 | Genome accession | NZ_AP019720 |
| Coordinates | 296179..296931 (+) | Length | 250 a.a. |
| NCBI ID | WP_002280234.1 | Uniprot ID | - |
| Organism | Streptococcus mutans strain NBRC 13955 | ||
| Function | activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation |
||
Genomic Context
Location: 291179..301931
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FNL60_RS01535 (SM3g_02690) | dnaI | 292090..292989 (+) | 900 | WP_002280235.1 | primosomal protein DnaI | - |
| FNL60_RS01540 (SM3g_02700) | der | 293002..294312 (+) | 1311 | WP_002265452.1 | ribosome biogenesis GTPase Der | - |
| FNL60_RS01545 (SM3g_02710) | - | 294387..295013 (+) | 627 | WP_002265453.1 | hypothetical protein | - |
| FNL60_RS01550 (SM3g_02720) | - | 295060..295698 (+) | 639 | WP_002265117.1 | VTT domain-containing protein | - |
| FNL60_RS01555 (SM3g_02730) | comE/blpR | 296179..296931 (+) | 753 | WP_002280234.1 | response regulator transcription factor | Regulator |
| FNL60_RS01560 (SM3g_02740) | comD/blpH | 296928..298253 (+) | 1326 | WP_002280233.1 | sensor histidine kinase | Regulator |
| FNL60_RS01565 (SM3g_02750) | comC/blpC | 298390..298536 (-) | 147 | WP_002280232.1 | ComC/BlpC family leader-containing pheromone/bacteriocin | Regulator |
| FNL60_RS01570 (SM3g_02760) | - | 298803..299024 (+) | 222 | WP_002312090.1 | Blp family class II bacteriocin | - |
| FNL60_RS01575 (SM3g_02770) | - | 299055..299273 (+) | 219 | WP_025985888.1 | Blp family class II bacteriocin | - |
| FNL60_RS01580 (SM3g_02780) | - | 299359..299763 (+) | 405 | WP_002280427.1 | hypothetical protein | - |
| FNL60_RS10455 | - | 299886..300098 (-) | 213 | Protein_277 | IS3 family transposase | - |
| FNL60_RS01595 (SM3g_02800) | - | 300538..300702 (+) | 165 | WP_002265308.1 | hypothetical protein | - |
| FNL60_RS01605 (SM3g_02810) | - | 301086..301277 (+) | 192 | WP_002312088.1 | Blp family class II bacteriocin | - |
| FNL60_RS01610 (SM3g_02820) | - | 301441..301629 (+) | 189 | WP_002280338.1 | Blp family class II bacteriocin | - |
Sequence
Protein
Download Length: 250 a.a. Molecular weight: 29361.71 Da Isoelectric Point: 8.2551
>NTDB_id=73508 FNL60_RS01555 WP_002280234.1 296179..296931(+) (comE/blpR) [Streptococcus mutans strain NBRC 13955]
MISIFVLEDDFLQQGRLETTIAAIMKEKNWSYKELTIFGKPQQLIDTIPEKGSHQIFFLDIEIKKEEKKGLEVANQIRQH
NPSAVIVFVTTHSEFMPLTFQYQVSALDFIDKSLNPEEFSHRIESALYYAMENSQKNGQSEELFIFHSSETQFQVPFAEI
LYFETSSTAHKLCLYTYDERIEFYGSMTDIVKMDKRLFQCHRSFIVNPANITRIDRKKRLAYFRNNKSCLISRTKLTKLR
AVIADQRRAK
MISIFVLEDDFLQQGRLETTIAAIMKEKNWSYKELTIFGKPQQLIDTIPEKGSHQIFFLDIEIKKEEKKGLEVANQIRQH
NPSAVIVFVTTHSEFMPLTFQYQVSALDFIDKSLNPEEFSHRIESALYYAMENSQKNGQSEELFIFHSSETQFQVPFAEI
LYFETSSTAHKLCLYTYDERIEFYGSMTDIVKMDKRLFQCHRSFIVNPANITRIDRKKRLAYFRNNKSCLISRTKLTKLR
AVIADQRRAK
Nucleotide
Download Length: 753 bp
>NTDB_id=73508 FNL60_RS01555 WP_002280234.1 296179..296931(+) (comE/blpR) [Streptococcus mutans strain NBRC 13955]
ATGATTTCTATTTTTGTATTGGAAGATGATTTTTTACAGCAAGGACGTCTTGAAACCACCATTGCAGCTATCATGAAAGA
AAAAAATTGGTCTTATAAAGAATTGACTATTTTTGGAAAACCACAACAACTTATTGATACTATCCCTGAAAAGGGCAGTC
ACCAGATTTTCTTTTTGGATATTGAAATCAAAAAAGAGGAAAAGAAAGGACTGGAAGTAGCCAATCAGATTAGACAGCAT
AATCCTAGTGCGGTTATTGTCTTTGTCACGACACATTCTGAGTTTATGCCCCTCACTTTTCAGTATCAGGTATCTGCTTT
GGATTTTATTGATAAATCTTTGAATCCTGAGGAGTTCTCCCACCGCATTGAATCAGCGCTGTATTATGCTATGGAAAACA
GCCAGAAGAATGGTCAATCAGAGGAACTTTTTATTTTCCATTCATCTGAAACTCAGTTTCAGGTCCCTTTTGCTGAGATT
CTGTATTTTGAAACATCTTCAACAGCCCATAAGCTCTGCCTTTATACTTATGATGAACGGATTGAATTCTACGGCAGTAT
GACTGACATTGTTAAAATGGATAAGAGACTTTTTCAGTGCCATCGCTCTTTTATTGTCAATCCTGCCAATATTACCCGTA
TTGATCGGAAAAAACGCTTGGCCTATTTTCGAAATAATAAGTCTTGTCTTATTTCACGAACTAAGTTAACAAAACTGAGA
GCTGTGATTGCTGATCAAAGGAGAGCAAAATGA
ATGATTTCTATTTTTGTATTGGAAGATGATTTTTTACAGCAAGGACGTCTTGAAACCACCATTGCAGCTATCATGAAAGA
AAAAAATTGGTCTTATAAAGAATTGACTATTTTTGGAAAACCACAACAACTTATTGATACTATCCCTGAAAAGGGCAGTC
ACCAGATTTTCTTTTTGGATATTGAAATCAAAAAAGAGGAAAAGAAAGGACTGGAAGTAGCCAATCAGATTAGACAGCAT
AATCCTAGTGCGGTTATTGTCTTTGTCACGACACATTCTGAGTTTATGCCCCTCACTTTTCAGTATCAGGTATCTGCTTT
GGATTTTATTGATAAATCTTTGAATCCTGAGGAGTTCTCCCACCGCATTGAATCAGCGCTGTATTATGCTATGGAAAACA
GCCAGAAGAATGGTCAATCAGAGGAACTTTTTATTTTCCATTCATCTGAAACTCAGTTTCAGGTCCCTTTTGCTGAGATT
CTGTATTTTGAAACATCTTCAACAGCCCATAAGCTCTGCCTTTATACTTATGATGAACGGATTGAATTCTACGGCAGTAT
GACTGACATTGTTAAAATGGATAAGAGACTTTTTCAGTGCCATCGCTCTTTTATTGTCAATCCTGCCAATATTACCCGTA
TTGATCGGAAAAAACGCTTGGCCTATTTTCGAAATAATAAGTCTTGTCTTATTTCACGAACTAAGTTAACAAAACTGAGA
GCTGTGATTGCTGATCAAAGGAGAGCAAAATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comE/blpR | Streptococcus mutans UA159 |
99.2 |
100 |
0.992 |
| comE/comE1 | Streptococcus equinus JB1 |
46.473 |
96.4 |
0.448 |
| comE | Streptococcus mitis NCTC 12261 |
41.7 |
98.8 |
0.412 |
| comE | Streptococcus infantis strain Atu-4 |
41.7 |
98.8 |
0.412 |
| comE | Streptococcus pneumoniae Rx1 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus mitis SK321 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus pneumoniae D39 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus pneumoniae R6 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus pneumoniae TIGR4 |
41.296 |
98.8 |
0.408 |
| comE/comE2 | Streptococcus equinus JB1 |
40.664 |
96.4 |
0.392 |
| comE/comE1 | Streptococcus gordonii str. Challis substr. CH1 |
37.551 |
98 |
0.368 |
| comE/comE2 | Streptococcus gordonii strain NCTC7865 |
37.551 |
98 |
0.368 |