Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   N2A96_RS00850 Genome accession   NZ_CP104047
Coordinates   137761..138702 (+) Length   313 a.a.
NCBI ID   WP_004347183.1    Uniprot ID   -
Organism   Streptococcus parauberis strain KSP10     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 132761..143702
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N2A96_RS00840 (N2A96_00840) rpoC 133597..137229 (+) 3633 WP_004347185.1 DNA-directed RNA polymerase subunit beta' -
  N2A96_RS00845 (N2A96_00845) - 137333..137707 (+) 375 WP_003103833.1 DUF1033 family protein -
  N2A96_RS00850 (N2A96_00850) comYA 137761..138702 (+) 942 WP_004347183.1 competence type IV pilus ATPase ComGA Machinery gene
  N2A96_RS00855 (N2A96_00855) comYB 138614..139669 (+) 1056 WP_142379024.1 competence type IV pilus assembly protein ComGB Machinery gene
  N2A96_RS00860 (N2A96_00860) comYC 139666..139992 (+) 327 WP_004347181.1 competence type IV pilus major pilin ComGC Machinery gene
  N2A96_RS00865 (N2A96_00865) comGD 139982..140389 (+) 408 WP_239639209.1 competence type IV pilus minor pilin ComGD -
  N2A96_RS00870 (N2A96_00870) comGE 140361..140660 (+) 300 WP_003104125.1 competence type IV pilus minor pilin ComGE -
  N2A96_RS00875 (N2A96_00875) comGF 140638..141075 (+) 438 WP_003102915.1 competence type IV pilus minor pilin ComGF -
  N2A96_RS00880 (N2A96_00880) comGG 141053..141550 (+) 498 WP_004347175.1 competence type IV pilus minor pilin ComGG -
  N2A96_RS00885 (N2A96_00885) comYH 141657..142613 (+) 957 WP_003103712.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 36251.59 Da        Isoelectric Point: 6.5048

>NTDB_id=727278 N2A96_RS00850 WP_004347183.1 137761..138702(+) (comYA) [Streptococcus parauberis strain KSP10]
MIQGLGKQIISEAMELQVQDIYILPEENGYQLFFRIHDERQKLENFQTSQLQQLMSHFKFLAGMNVGEKRRCQLGSCNYD
IDDSISISLRLSTVGDYRGRESMVIRILYPYQENQTYWEDMDEKINQFIIGRGLYLFAGPVGSGKTSLMYRLIEKNFHDR
QVITIEDPVEIKNPKFLQLQVNDSIGMTYDNLIKLSLRHRPDILVIGEIRDRETAQAVIRASLTGIMVFSTVHAKSVPGV
YYRLLELGINQNELENALRLIVYQRLMGGKGLIDFTNKNYISHSHEKWNQAIDQLVAKGHFPEEKGEKEKIIE

Nucleotide


Download         Length: 942 bp        

>NTDB_id=727278 N2A96_RS00850 WP_004347183.1 137761..138702(+) (comYA) [Streptococcus parauberis strain KSP10]
ATGATCCAAGGTTTGGGTAAGCAAATAATAAGTGAAGCGATGGAGTTGCAAGTTCAAGATATCTATATTTTACCTGAAGA
GAATGGGTATCAATTGTTTTTCCGAATTCATGATGAAAGGCAAAAATTAGAAAATTTTCAAACAAGTCAATTACAACAAT
TAATGAGTCATTTTAAGTTTTTGGCTGGTATGAATGTTGGCGAAAAAAGAAGGTGTCAGTTAGGTTCTTGTAATTATGAT
ATAGATGATTCTATATCAATCTCATTAAGACTTTCTACAGTTGGTGATTATCGTGGGCGTGAAAGTATGGTTATTCGTAT
TCTTTATCCTTATCAAGAGAATCAAACCTATTGGGAGGATATGGATGAAAAAATTAATCAATTTATAATCGGACGTGGAC
TCTATCTTTTTGCTGGACCAGTTGGATCAGGTAAAACAAGTCTAATGTATAGACTTATTGAGAAAAATTTCCATGACAGG
CAAGTGATTACGATTGAGGATCCAGTTGAAATAAAGAATCCCAAATTCTTACAATTACAAGTTAATGATAGTATTGGAAT
GACTTATGATAATCTCATAAAGTTATCTCTGCGTCATCGACCGGATATTTTAGTAATTGGTGAAATTCGAGATAGGGAGA
CTGCACAGGCTGTGATTAGAGCAAGTTTAACAGGAATTATGGTCTTTTCAACAGTACATGCAAAAAGTGTTCCAGGGGTA
TATTATCGCCTTTTAGAATTAGGAATTAATCAAAATGAATTAGAAAACGCCTTAAGATTAATAGTTTATCAAAGATTAAT
GGGAGGGAAAGGTTTAATTGATTTTACTAACAAAAACTATATTAGTCATTCGCATGAAAAATGGAATCAAGCTATTGATC
AGTTGGTTGCAAAAGGACATTTCCCTGAAGAAAAAGGGGAAAAAGAAAAGATTATCGAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

60.897

99.681

0.607
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.968

99.042

0.604
  comYA Streptococcus mutans UA140

60.577

99.681

0.604
  comYA Streptococcus gordonii str. Challis substr. CH1

56.913

99.361

0.565
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

55.769

99.681

0.556
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

55.769

99.681

0.556
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

55.769

99.681

0.556
  comGA/cglA/cilD Streptococcus pneumoniae D39

55.769

99.681

0.556
  comGA/cglA/cilD Streptococcus pneumoniae R6

55.769

99.681

0.556
  comGA Lactococcus lactis subsp. cremoris KW2

51.768

99.361

0.514
  comGA Latilactobacillus sakei subsp. sakei 23K

42.545

87.859

0.374