Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   N2A96_RS00855 Genome accession   NZ_CP104047
Coordinates   138614..139669 (+) Length   351 a.a.
NCBI ID   WP_142379024.1    Uniprot ID   -
Organism   Streptococcus parauberis strain KSP10     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 133614..144669
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N2A96_RS00845 (N2A96_00845) - 137333..137707 (+) 375 WP_003103833.1 DUF1033 family protein -
  N2A96_RS00850 (N2A96_00850) comYA 137761..138702 (+) 942 WP_004347183.1 competence type IV pilus ATPase ComGA Machinery gene
  N2A96_RS00855 (N2A96_00855) comYB 138614..139669 (+) 1056 WP_142379024.1 competence type IV pilus assembly protein ComGB Machinery gene
  N2A96_RS00860 (N2A96_00860) comYC 139666..139992 (+) 327 WP_004347181.1 competence type IV pilus major pilin ComGC Machinery gene
  N2A96_RS00865 (N2A96_00865) comGD 139982..140389 (+) 408 WP_239639209.1 competence type IV pilus minor pilin ComGD -
  N2A96_RS00870 (N2A96_00870) comGE 140361..140660 (+) 300 WP_003104125.1 competence type IV pilus minor pilin ComGE -
  N2A96_RS00875 (N2A96_00875) comGF 140638..141075 (+) 438 WP_003102915.1 competence type IV pilus minor pilin ComGF -
  N2A96_RS00880 (N2A96_00880) comGG 141053..141550 (+) 498 WP_004347175.1 competence type IV pilus minor pilin ComGG -
  N2A96_RS00885 (N2A96_00885) comYH 141657..142613 (+) 957 WP_003103712.1 class I SAM-dependent methyltransferase Machinery gene
  N2A96_RS00890 (N2A96_00890) - 142669..143862 (+) 1194 WP_004347172.1 acetate kinase -
  N2A96_RS00895 (N2A96_00895) - 143973..144185 (+) 213 WP_003108636.1 helix-turn-helix transcriptional regulator -
  N2A96_RS00900 (N2A96_00900) - 144178..144630 (+) 453 WP_003108634.1 hypothetical protein -

Sequence

Protein


Download         Length: 351 a.a.        Molecular weight: 40450.56 Da        Isoelectric Point: 9.8777

>NTDB_id=727279 N2A96_RS00855 WP_142379024.1 138614..139669(+) (comYB) [Streptococcus parauberis strain KSP10]
MKNGIKLLISWLQKDISLKKKGKKKRLSSKKQYQLIQLLHNLQASGFNLVEMVSFLKKSKLISEEQVKIMEFHMLNGSSL
SKIMLDLGYPDSIITQLSLAELHGNILGSLENIETYLLQVNHIKKKTFEVVMYPLVLLFFLTTILLGLRQYLLPSLNEEG
PLMFLLTYFPHLLIILIVIILFVSIVVIYKWRRSSPLKLISQISRLPLIGYVIQLYMTAFYAREWGNLLDQGLELSMILS
VMSKEKSLLVREIGIEMNSAFVEGIPFEQKVLDYPFFKNELSLIISYGQVKSKLGKELEIYSQNTWESYFRFLIQLTQLI
QPIVFLAVALIIVMIYAAMLLPIYQNMGGNL

Nucleotide


Download         Length: 1056 bp        

>NTDB_id=727279 N2A96_RS00855 WP_142379024.1 138614..139669(+) (comYB) [Streptococcus parauberis strain KSP10]
ATGAAAAATGGAATCAAGCTATTGATCAGTTGGTTGCAAAAGGACATTTCCCTGAAGAAAAAGGGGAAAAAGAAAAGATT
ATCGAGTAAAAAACAATATCAACTTATCCAATTGTTACATAATCTCCAAGCAAGCGGATTTAATTTAGTTGAAATGGTAT
CTTTTCTGAAGAAAAGTAAATTAATATCTGAAGAGCAGGTTAAAATTATGGAATTTCACATGCTCAATGGCAGTAGTTTA
TCAAAAATCATGCTTGATTTAGGTTACCCAGATAGTATTATAACTCAATTGAGTTTAGCAGAATTACATGGGAATATTTT
GGGGAGTCTTGAAAATATAGAAACATACCTTTTGCAAGTGAATCATATTAAAAAGAAAACTTTCGAAGTGGTAATGTATC
CACTTGTATTACTATTTTTTCTAACAACTATACTACTTGGTTTGAGACAATATTTATTGCCTTCGCTTAATGAGGAAGGT
CCACTTATGTTCCTACTAACCTATTTTCCTCACCTTTTAATAATCCTAATTGTGATAATCCTCTTTGTCTCTATAGTAGT
TATTTATAAATGGCGACGTAGTTCACCACTCAAGCTAATTAGCCAAATTAGTCGATTGCCTTTAATAGGATACGTCATCC
AGTTATATATGACAGCCTTCTATGCTCGAGAATGGGGAAATTTATTAGATCAGGGGCTTGAATTAAGTATGATTTTGTCT
GTTATGAGTAAGGAAAAATCACTTTTGGTACGGGAAATAGGTATAGAAATGAATAGTGCTTTTGTAGAGGGGATTCCGTT
TGAGCAAAAGGTACTAGATTATCCATTTTTTAAAAATGAATTGAGTTTAATTATTTCATATGGACAAGTTAAATCAAAAT
TAGGGAAGGAGTTAGAAATATATTCTCAAAATACATGGGAGTCTTACTTCAGGTTCCTCATACAACTTACTCAGCTGATT
CAACCAATTGTATTTTTAGCAGTTGCTCTAATTATTGTCATGATTTATGCAGCAATGCTATTGCCAATTTATCAAAATAT
GGGAGGAAATTTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(36-154)

Type II secretion system (T2SS), protein F (T2SSF)

(222-342)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

51.304

98.291

0.504
  comYB Streptococcus mutans UA159

51.304

98.291

0.504
  comYB Streptococcus gordonii str. Challis substr. CH1

47.368

97.436

0.462
  comGB/cglB Streptococcus mitis NCTC 12261

46.765

96.866

0.453
  comGB/cglB Streptococcus mitis SK321

45.401

96.011

0.436
  comGB/cglB Streptococcus pneumoniae Rx1

45.104

96.011

0.433
  comGB/cglB Streptococcus pneumoniae D39

45.104

96.011

0.433
  comGB/cglB Streptococcus pneumoniae R6

45.104

96.011

0.433
  comGB/cglB Streptococcus pneumoniae TIGR4

45.104

96.011

0.433
  comGB Lactococcus lactis subsp. cremoris KW2

41.935

97.151

0.407