Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   NQZ84_RS07235 Genome accession   NZ_CP102094
Coordinates   1466172..1466909 (-) Length   245 a.a.
NCBI ID   WP_257048495.1    Uniprot ID   -
Organism   Streptococcus suis strain 12RC1     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1456578..1467803 1466172..1466909 within 0


Gene organization within MGE regions


Location: 1456578..1467803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ84_RS07165 (NQZ84_07165) - 1456578..1456781 (-) 204 WP_044677453.1 hypothetical protein -
  NQZ84_RS07170 (NQZ84_07170) - 1457626..1458048 (-) 423 WP_024407031.1 hypothetical protein -
  NQZ84_RS07175 (NQZ84_07175) - 1458071..1458307 (-) 237 WP_024407030.1 Blp family class II bacteriocin -
  NQZ84_RS07180 (NQZ84_07180) - 1458495..1459856 (-) 1362 WP_257048476.1 bacteriocin secretion accessory protein -
  NQZ84_RS07185 (NQZ84_07185) comA 1459866..1462016 (-) 2151 WP_044680882.1 peptide cleavage/export ABC transporter ComA Regulator
  NQZ84_RS07190 (NQZ84_07190) - 1462120..1462311 (-) 192 WP_044680883.1 hypothetical protein -
  NQZ84_RS07195 (NQZ84_07195) - 1462337..1462534 (-) 198 WP_044680884.1 hypothetical protein -
  NQZ84_RS07200 (NQZ84_07200) - 1462547..1462750 (-) 204 WP_044680885.1 hypothetical protein -
  NQZ84_RS07205 (NQZ84_07205) - 1462927..1463052 (-) 126 WP_141590538.1 bacteriocin -
  NQZ84_RS07210 (NQZ84_07210) - 1463063..1463206 (-) 144 WP_205029660.1 hypothetical protein -
  NQZ84_RS07215 (NQZ84_07215) - 1463455..1463679 (-) 225 WP_024379520.1 hypothetical protein -
  NQZ84_RS07220 (NQZ84_07220) - 1463692..1464396 (-) 705 WP_257048513.1 ParA family protein -
  NQZ84_RS07225 (NQZ84_07225) - 1464685..1464813 (+) 129 WP_257048491.1 hypothetical protein -
  NQZ84_RS07230 (NQZ84_07230) - 1464835..1466175 (-) 1341 WP_228475577.1 sensor histidine kinase -
  NQZ84_RS07235 (NQZ84_07235) comE/blpR 1466172..1466909 (-) 738 WP_257048495.1 response regulator transcription factor Regulator
  NQZ84_RS07240 (NQZ84_07240) - 1466913..1467245 (-) 333 WP_024407025.1 LytTR family DNA-binding domain-containing protein -
  NQZ84_RS07245 (NQZ84_07245) - 1467435..1467803 (+) 369 WP_044677450.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28380.36 Da        Isoelectric Point: 6.3055

>NTDB_id=714306 NQZ84_RS07235 WP_257048495.1 1466172..1466909(-) (comE/blpR) [Streptococcus suis strain 12RC1]
MLNIFVLEDDFFQQSRLENAIRRCVEETSVRYKFLEVFGKPNQLLESIEEAGNHQFFFLDIEIKGEEKKGMEIAKEIRAR
DPYGVIVFVTTHSEFMPVTYRYRVSALDFIDKGLEDSDFRKAVSDVLVHAFENIDHTVAENSFVYKTETAHIQVPFSDIL
YFETSSTIHKVILKTKTGQTEFYGKVSDIAKADKRLYQAHRSCVVNPLNITKLDRANHIAYFENGDSCFVSRLKQKKLAD
LLEIK

Nucleotide


Download         Length: 738 bp        

>NTDB_id=714306 NQZ84_RS07235 WP_257048495.1 1466172..1466909(-) (comE/blpR) [Streptococcus suis strain 12RC1]
ATGCTTAATATTTTTGTATTAGAAGATGATTTTTTTCAGCAGAGTAGGTTAGAAAATGCTATTAGGCGGTGTGTTGAAGA
AACGTCAGTAAGATATAAATTTCTAGAAGTTTTTGGTAAACCAAATCAGTTATTGGAATCAATTGAGGAAGCAGGCAATC
ACCAATTTTTCTTTTTAGATATTGAAATAAAAGGCGAAGAAAAGAAAGGAATGGAAATCGCTAAAGAAATCCGTGCTCGA
GATCCTTATGGTGTTATTGTCTTTGTAACAACTCACTCAGAATTTATGCCGGTAACGTATCGTTATCGGGTTTCTGCTTT
AGATTTTATAGATAAAGGTCTGGAGGATAGTGACTTTCGAAAGGCAGTATCAGATGTGTTAGTACATGCTTTTGAAAATA
TTGATCATACTGTAGCTGAAAATTCTTTTGTATACAAAACTGAAACTGCTCATATTCAAGTCCCTTTTAGTGACATCCTT
TATTTTGAAACATCATCAACGATTCATAAAGTCATTTTAAAAACCAAAACAGGTCAGACTGAATTTTACGGGAAAGTATC
GGATATAGCGAAAGCTGATAAACGACTTTACCAAGCACATCGTTCTTGTGTAGTGAATCCTTTAAATATAACGAAGTTGG
ATAGAGCAAACCACATTGCCTATTTTGAGAATGGAGATTCTTGTTTTGTTTCTCGTTTGAAGCAGAAGAAACTTGCAGAT
TTGCTGGAGATTAAATGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-242)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

55.23

97.551

0.539
  comE/comE1 Streptococcus equinus JB1

50

97.143

0.486
  comE/comE2 Streptococcus equinus JB1

40.329

99.184

0.4
  comE Streptococcus pneumoniae TIGR4

38.645

100

0.396
  comE Streptococcus pneumoniae D39

38.645

100

0.396
  comE Streptococcus pneumoniae R6

38.645

100

0.396
  comE Streptococcus infantis strain Atu-4

38.645

100

0.396
  comE Streptococcus mitis NCTC 12261

38.645

100

0.396
  comE Streptococcus mitis SK321

38.645

100

0.396
  comE Streptococcus pneumoniae Rx1

38.645

100

0.396
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.71

100

0.392
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.71

100

0.392