Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   NQZ84_RS07185 Genome accession   NZ_CP102094
Coordinates   1459866..1462016 (-) Length   716 a.a.
NCBI ID   WP_044680882.1    Uniprot ID   A0AB33U9D2
Organism   Streptococcus suis strain 12RC1     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1456578..1467803 1459866..1462016 within 0


Gene organization within MGE regions


Location: 1456578..1467803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ84_RS07165 (NQZ84_07165) - 1456578..1456781 (-) 204 WP_044677453.1 hypothetical protein -
  NQZ84_RS07170 (NQZ84_07170) - 1457626..1458048 (-) 423 WP_024407031.1 hypothetical protein -
  NQZ84_RS07175 (NQZ84_07175) - 1458071..1458307 (-) 237 WP_024407030.1 Blp family class II bacteriocin -
  NQZ84_RS07180 (NQZ84_07180) - 1458495..1459856 (-) 1362 WP_257048476.1 bacteriocin secretion accessory protein -
  NQZ84_RS07185 (NQZ84_07185) comA 1459866..1462016 (-) 2151 WP_044680882.1 peptide cleavage/export ABC transporter ComA Regulator
  NQZ84_RS07190 (NQZ84_07190) - 1462120..1462311 (-) 192 WP_044680883.1 hypothetical protein -
  NQZ84_RS07195 (NQZ84_07195) - 1462337..1462534 (-) 198 WP_044680884.1 hypothetical protein -
  NQZ84_RS07200 (NQZ84_07200) - 1462547..1462750 (-) 204 WP_044680885.1 hypothetical protein -
  NQZ84_RS07205 (NQZ84_07205) - 1462927..1463052 (-) 126 WP_141590538.1 bacteriocin -
  NQZ84_RS07210 (NQZ84_07210) - 1463063..1463206 (-) 144 WP_205029660.1 hypothetical protein -
  NQZ84_RS07215 (NQZ84_07215) - 1463455..1463679 (-) 225 WP_024379520.1 hypothetical protein -
  NQZ84_RS07220 (NQZ84_07220) - 1463692..1464396 (-) 705 WP_257048513.1 ParA family protein -
  NQZ84_RS07225 (NQZ84_07225) - 1464685..1464813 (+) 129 WP_257048491.1 hypothetical protein -
  NQZ84_RS07230 (NQZ84_07230) - 1464835..1466175 (-) 1341 WP_228475577.1 sensor histidine kinase -
  NQZ84_RS07235 (NQZ84_07235) comE/blpR 1466172..1466909 (-) 738 WP_257048495.1 response regulator transcription factor Regulator
  NQZ84_RS07240 (NQZ84_07240) - 1466913..1467245 (-) 333 WP_024407025.1 LytTR family DNA-binding domain-containing protein -
  NQZ84_RS07245 (NQZ84_07245) - 1467435..1467803 (+) 369 WP_044677450.1 hypothetical protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 80666.62 Da        Isoelectric Point: 6.9796

>NTDB_id=714305 NQZ84_RS07185 WP_044680882.1 1459866..1462016(-) (comA) [Streptococcus suis strain 12RC1]
MRFKKKHYRAQVDTRDCGVASLAMVFGFYGSYYSLATLRELAKTTQEGTTAFGLVKVAEGEGFETRAIRADMTLFDEDII
YPFIAHVVKNGNLMHYYVVTGCDKKSIHIADPDPTVKLKKMPREQFEEEWTGVSIFIAPTPSYKVHKEKKDSLLSFVPIL
ARQKGLILNIVVATLIVTIINIVGSYYLQSIIDTYIPEQVKNTLSIVSVGLVIVYILQQLISYAQEYLLLVLGQRLSIDV
ILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSVFLDVSIIIIVSIVLFSQNINLFFISLLALPIYTVI
ILSFMKPFEKMNQETMESNAVLSSSIIEDINGIETIKSLTSERQRYQKIDKEFVDYLKKSFAYGRAESIQKTLKRLAQLL
LNVAVLWMGANLVMDNKMTLGQLITYNSLLVYFTNPLENIINLQTKLQTAKVANNRLNEVYLVKSEFEEQKTVHDLSHFK
GNLTFNSVSYKYGYGRDVLSDINLTLKAGSKVSFVGISGSGKTTLAKMLVNFFSPSKGEILLDDVNLEDINKESLRRYIN
YLPQQPYVFNGTILDNLLLGAKEGTTQEDIFRAVQIAEIKSDIESMPLNYQTELTSDGVGISGGQRQRIALARALLTDSP
VLILDEATSSLDVLTEKKIIDNLMELDKTLIFIAHRLTISERTEHIVVLDKGKIIEEGTHQDLLQKQGFYAHLVNS

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=714305 NQZ84_RS07185 WP_044680882.1 1459866..1462016(-) (comA) [Streptococcus suis strain 12RC1]
ATGCGTTTTAAGAAGAAACATTATCGTGCTCAAGTAGATACTAGGGACTGCGGTGTTGCCTCTCTGGCAATGGTTTTTGG
TTTCTATGGGTCATATTATTCGTTGGCTACTTTGCGTGAATTGGCGAAGACTACGCAAGAGGGGACAACAGCTTTTGGAT
TGGTCAAAGTTGCTGAAGGTGAAGGATTTGAAACTCGAGCAATCCGTGCAGATATGACTCTTTTTGATGAGGATATCATC
TATCCTTTTATTGCCCATGTAGTCAAAAATGGTAATTTGATGCACTATTATGTGGTAACAGGATGTGATAAGAAATCAAT
TCATATCGCTGACCCAGATCCAACTGTGAAACTGAAGAAAATGCCACGTGAGCAGTTTGAAGAGGAATGGACAGGAGTTT
CAATTTTCATCGCTCCAACTCCGAGCTATAAGGTTCACAAAGAAAAGAAAGATAGCCTATTATCTTTTGTCCCTATCCTT
GCTAGACAGAAGGGACTGATATTAAATATTGTCGTTGCCACTCTTATAGTGACTATAATCAATATTGTTGGTTCTTACTA
TCTACAATCGATTATAGATACCTATATTCCTGAACAGGTAAAAAATACTCTAAGCATTGTGTCAGTTGGATTAGTTATCG
TCTATATTCTTCAACAACTGATTTCTTATGCTCAAGAGTACTTATTATTGGTCCTGGGGCAGAGATTATCAATTGATGTT
ATTTTGTCTTATATCAAGCATGTTTTTCACTTGCCGATGTCTTTCTTTGCAACAAGAAGAACAGGGGAAATCGTTTCACG
TTTCACTGATGCTAATTCAATCATCGATGCTTTAGCAAGTACGATTTTATCGGTTTTCTTAGATGTTTCGATTATCATCA
TTGTTTCAATTGTTTTGTTTTCTCAAAACATTAACCTATTTTTCATTAGCTTACTTGCATTGCCAATCTATACCGTGATT
ATCTTATCTTTCATGAAACCATTCGAAAAAATGAATCAAGAAACAATGGAATCTAATGCGGTCCTATCATCTTCAATCAT
TGAAGATATTAACGGTATTGAGACAATCAAGTCCTTAACAAGTGAACGACAACGTTATCAAAAGATTGATAAGGAATTTG
TCGATTATTTGAAGAAGTCATTTGCTTACGGTAGAGCGGAGAGTATTCAGAAAACGCTAAAAAGATTAGCTCAGTTATTG
CTGAATGTTGCGGTATTATGGATGGGAGCAAATCTTGTTATGGATAATAAGATGACTTTGGGGCAGCTTATTACCTATAA
CTCTTTATTGGTCTATTTCACAAACCCTCTGGAAAATATTATTAACCTTCAGACGAAGTTACAAACTGCTAAAGTTGCAA
ATAACCGCCTAAATGAAGTATACCTGGTAAAATCTGAATTTGAAGAGCAAAAAACAGTTCATGATTTGAGCCATTTCAAA
GGGAATCTAACATTCAACAGTGTCAGCTATAAGTATGGATATGGTAGAGATGTTCTTAGTGACATTAATCTCACATTGAA
AGCAGGTAGTAAGGTGTCATTTGTAGGAATTTCAGGTTCAGGAAAAACTACATTGGCCAAGATGCTTGTTAACTTCTTTA
GTCCATCAAAGGGTGAGATTTTATTAGATGATGTGAATCTAGAAGATATTAACAAAGAAAGTCTTCGAAGATATATCAAT
TATCTACCTCAACAGCCGTATGTTTTTAATGGTACTATCCTGGATAATCTTTTGCTAGGAGCAAAAGAGGGAACGACTCA
GGAAGATATTTTTAGAGCAGTTCAAATCGCAGAAATCAAGTCCGATATAGAATCTATGCCGTTGAACTATCAAACAGAAT
TAACGTCAGATGGTGTTGGTATTTCAGGAGGTCAGCGTCAGAGGATTGCCTTGGCTAGAGCCTTATTGACGGATTCTCCA
GTATTGATTTTGGATGAGGCAACCAGTAGCTTAGATGTATTGACTGAGAAGAAAATCATAGATAATCTTATGGAATTAGA
TAAGACATTGATTTTCATTGCTCATAGATTAACAATTTCTGAGAGAACGGAGCATATCGTTGTCCTTGATAAAGGCAAAA
TTATTGAAGAAGGAACTCATCAAGATTTGCTGCAGAAACAAGGATTTTATGCTCATTTAGTAAATAGTTAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(499-649)

Peptidase C39 family (Peptidase_C39)

(6-141)

ABC transporter transmembrane region (ABC_membrane)

(168-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

81.032

100

0.811
  comA Streptococcus pneumoniae Rx1

80.753

100

0.809
  comA Streptococcus pneumoniae D39

80.753

100

0.809
  comA Streptococcus pneumoniae R6

80.753

100

0.809
  comA Streptococcus mitis SK321

80.474

100

0.806
  comA Streptococcus pneumoniae TIGR4

80.474

100

0.806
  comA Streptococcus gordonii str. Challis substr. CH1

75.453

100

0.756
  comA/nlmT Streptococcus mutans UA159

63.459

100

0.635