Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   NPS18_RS09200 Genome accession   NZ_CP101984
Coordinates   1855436..1856377 (-) Length   313 a.a.
NCBI ID   WP_002263435.1    Uniprot ID   -
Organism   Streptococcus mutans strain UA-159     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1850436..1861377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS18_RS09160 (NPS18_09160) - 1850445..1851644 (-) 1200 WP_002263443.1 acetate kinase -
  NPS18_RS09165 (NPS18_09165) comYH 1851703..1852656 (-) 954 WP_002263442.1 class I SAM-dependent methyltransferase Machinery gene
  NPS18_RS09170 (NPS18_09170) comYG 1852711..1853100 (-) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  NPS18_RS09175 (NPS18_09175) comYF 1853078..1853512 (-) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  NPS18_RS09180 (NPS18_09180) comYE 1853499..1853792 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  NPS18_RS09185 (NPS18_09185) comYD 1853764..1854168 (-) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  NPS18_RS09190 (NPS18_09190) comYC 1854155..1854469 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  NPS18_RS09195 (NPS18_09195) comYB 1854469..1855500 (-) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  NPS18_RS09200 (NPS18_09200) comYA 1855436..1856377 (-) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  NPS18_RS09205 (NPS18_09205) - 1856507..1856890 (-) 384 WP_002263434.1 DUF1033 family protein -
  NPS18_RS09210 (NPS18_09210) rpoC 1857018..1860647 (-) 3630 WP_002263433.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35739.09 Da        Isoelectric Point: 8.0347

>NTDB_id=713536 NPS18_RS09200 WP_002263435.1 1855436..1856377(-) (comYA) [Streptococcus mutans strain UA-159]
MVQKLGRKIIAEAVQNKAQDIYIIPKKESYELYMRIGNERRFIDVYDHHFMANLISHFKFVAGMNVGEKRRSQLGSCDYS
YDEGKVISLRLSSVGDYRGYESLVIRLLFSGRHDLKFWFNSMDLILNEIKGRGLYLFSGPVGSGKTSLMYQLVKLRFETK
QVITIEDPVEIKQDNMLQLQLNESIDMTYDNLIKLSLRHRPDILIIGEIRDKETARAVIRASLTGAMVFSTIHAKSIPGV
YARMLELGTSSEELQNALRGIVYQRLIGGGGIIDFAKGDYQNHSAKKWNKQIYDLFTAGYITEGEAQAEEIED

Nucleotide


Download         Length: 942 bp        

>NTDB_id=713536 NPS18_RS09200 WP_002263435.1 1855436..1856377(-) (comYA) [Streptococcus mutans strain UA-159]
ATGGTTCAAAAATTAGGTAGAAAAATCATTGCCGAAGCTGTTCAAAATAAAGCACAAGATATCTATATTATTCCTAAAAA
AGAATCTTATGAGCTTTATATGAGAATAGGGAATGAAAGGAGGTTCATTGATGTTTATGACCATCATTTCATGGCTAATC
TTATTAGTCACTTTAAATTTGTTGCAGGAATGAATGTTGGTGAGAAAAGACGAAGTCAGCTGGGCTCTTGTGATTATTCT
TATGATGAAGGGAAAGTTATTTCATTAAGGTTATCAAGTGTAGGAGATTATCGTGGTTATGAAAGTTTGGTTATTCGCTT
ACTTTTTTCTGGACGTCACGATTTAAAATTCTGGTTTAACAGTATGGATTTGATTTTAAATGAAATCAAGGGGCGAGGGC
TTTATCTTTTTTCGGGTCCAGTTGGAAGTGGCAAAACAAGTTTGATGTATCAATTGGTAAAACTAAGATTTGAGACCAAA
CAGGTAATTACCATTGAAGATCCTGTGGAAATTAAGCAAGATAATATGTTACAACTGCAGCTTAATGAAAGCATTGATAT
GACTTATGATAATTTAATTAAATTATCTCTGAGGCATCGTCCGGATATTTTAATTATTGGAGAAATTCGAGATAAAGAAA
CCGCCAGAGCTGTTATTAGAGCAAGTCTTACAGGGGCAATGGTATTCTCAACTATCCATGCTAAAAGCATTCCAGGTGTT
TATGCTAGGATGTTAGAATTGGGTACTAGTTCAGAAGAATTACAAAATGCTTTGCGTGGTATTGTTTATCAACGTTTAAT
AGGGGGAGGAGGGATTATTGACTTTGCCAAAGGGGATTATCAAAACCACTCAGCAAAAAAGTGGAACAAACAAATTTATG
ACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

100

100

1
  comYA Streptococcus mutans UA140

99.681

100

0.997
  comYA Streptococcus gordonii str. Challis substr. CH1

67.093

100

0.671
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

66.026

99.681

0.658
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.916

99.361

0.655
  comGA Lactococcus lactis subsp. cremoris KW2

52.412

99.361

0.521